Annotation Detail for ARFGAP2

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Basic Information Top

Gene Symbol:	ARFGAP2 ( FLJ14576,FLJ26000,IRZ,ZNF289,Zfp289 )
Gene Full Name:	ADP-ribosylation factor GTPase activating protein 2
Band:	11p11.2
Quick Links	Entrez ID:84364; OMIM: 606908; Uniprot ID:ARFG2_HUMAN; ENSEMBL ID: ENSG00000149182; HGNC ID: 13504
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:5 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
146	Phosphoserine.
337	Phosphoserine (By similarity).
368	Phosphoserine.
432	Phosphoserine.
498	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_032389
Location:chr11 47142429-47154994
strand:-

Upstream the gene:1 results
Downstream the gene:0 results
Inside the gene:12 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	47154609	47155994	1385	307

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
FOXA1	MCF7	GSE15244	47153917	47154841	924	0
H3K4me3	colorectal	cancer	47153289	47154868	1579	0
H3ac	HepG2	E	47152862	47154941	2079	0
NRSF	pAb	Jurkat	47143687	47143965	278	0
NRSF	pAb	Jurkat	47150414	47150627	213	0
P300	T0-glioblastoma	GSE21026	47154619	47155345	726	0
P300	T30-glioblastoma	GSE21026	47153836	47156076	2240	0
RARG	MCF7	GSE15244	47152947	47154599	1652	0
TAF	Hela	GSE8489	47146336	47146624	288	0
TAF	Hela	GSE8489	47153848	47154799	951	0
hScc1	Bcell	GSE12603	47144293	47144964	671	0
hScc1	Bcell	GSE12603	47149617	47150132	515	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
4390	mRNA	MGC4707	chr11	46914826	47142505	78	mRNA	ZNF289	chr11	47142427	47154995	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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