AutismKB 2.0

Annotation Detail for DYRK3


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Basic Information Top
Gene Symbol:DYRK3 ( DYRK5,RED,REDK,hYAK3-2 )
Gene Full Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Band: 1q32.1
Quick LinksEntrez ID:8444; OMIM: 603497; Uniprot ID:DYRK3_HUMAN; ENSEMBL ID: ENSG00000143479; HGNC ID: 3094
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
209Phosphotyrosine.
318Phosphoserine (By similarity).
369Phosphotyrosine.
Location(AA) Modifications Resource
209Phosphotyrosine.Swiss-Prot 53.0
209PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
52N-linkedHMM predict
63N-linkedHMM predict
106Phosphoserine(ATM)HMM predict
114O-linkedHMM predict
116Phosphoserine(ATM)HMM predict
129O-linkedHMM predict
130N-linkedHMM predict
131Phosphoserine(CDC2)HMM predict
142Phosphothreonine(MAPK)HMM predict
157Phosphotyrosine(EGFR)HMM predict
190Phosphotyrosine(INSR)HMM predict
207Phosphotyrosine(Jak)HMM predict
512Phosphothreonine(MAPK)HMM predict
574N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003582
  • Location:chr1 204875503-204889163
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 204874247 204874543 296 1109
CTCF CD4SISSRdata 204874247 204874543 296 1109
CTCF G2GSE9613 204874288 204874796 508 962
H3ac HepG2E 204874873 204875248 375 443
Myc K562GSE19551 204874261 204875855 1594 446
Myc hESGSE17917 204875231 204875487 256 145
PHF8 HeLaGSE20725 204874795 204875940 1145 136
hScc1 BcellGSE12603 204874246 204874724 478 1019
hScc1 CdLSGSE12603 204873927 204874760 833 1160
p63 keratinocytesGSE17611 204873396 204874138 742 1737
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 204898526 204898820 294 9510
CTCF CD4GSE12889 204904181 204904448 267 15151
CTCF CD4SISSRdata 204898526 204898820 294 9510
CTCF CD4SISSRdata 204904181 204904448 267 15151
CTCF JurkatGSE12889 204898427 204898812 385 9456
CTCF G2GSE9613 204898444 204899533 1089 9825
CTCF G2GSE9613 204903788 204904809 1021 15135
hScc1 BcellGSE12603 204895565 204895742 177 6490
hScc1 BcellGSE12603 204898480 204899055 575 9604
hScc1 BcellGSE12603 204903860 204904736 876 15135
hScc1 CdLSGSE12603 204898385 204898988 603 9523
hScc1 CdLSGSE12603 204903825 204904774 949 15136
hScc1 G2GSE9613 204903860 204904809 949 15171
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 204875315 204875735 420 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2236 mRNA DYRK3 chr1 203197275 203210936 23 EST chr1 203196389 203197362Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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