AutismKB 2.0

Annotation Detail for LZTS2


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Basic Information Top
Gene Symbol:LZTS2 ( KIAA1813,LAPSER1 )
Gene Full Name: leucine zipper, putative tumor suppressor 2
Band: 10q24.31
Quick LinksEntrez ID:84445; OMIM: 610454; Uniprot ID:LZTS2_HUMAN; ENSEMBL ID: ENSG00000107816; HGNC ID: 29381
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
570Phosphoserine.
640Nuclear export signal.
Location(AA) Modifications Resource
Location(AA) Modification Resource
90Phosphotyrosine(INSR)HMM predict
99Phosphoserine(IKK)HMM predict
99Phosphoserine(ATM)HMM predict
102Phosphoserine(IKK)HMM predict
102Phosphoserine(ATM)HMM predict
102Phosphoserine(CDC2)HMM predict
102Phosphoserine(MAPK)HMM predict
102O-linkedHMM predict
175Phosphoserine(ATM)HMM predict
188O-linkedHMM predict
195Phosphoserine(CK1)HMM predict
210O-linkedHMM predict
214Phosphoserine(IKK)HMM predict
224Phosphoserine(PKG)HMM predict
227Phosphoserine(CK1)HMM predict
230O-linkedHMM predict
232O-linkedHMM predict
239O-linkedHMM predict
240O-linkedHMM predict
241O-linkedHMM predict
241Phosphoserine(CK1)HMM predict
242Phosphoserine(CDC2)HMM predict
242O-linkedHMM predict
254MethylarginineHMM predict
269O-linkedHMM predict
277Phosphoserine(CDC2)HMM predict
279Phosphoserine(CK1)HMM predict
301Phosphoserine(MAPK)HMM predict
301Phosphoserine(CDC2)HMM predict
301O-linkedHMM predict
311O-linkedHMM predict
320O-linkedHMM predict
320O-linkedHMM predict
346Phosphoserine(CK1)HMM predict
460Phosphoserine(ATM)HMM predict
484Phosphothreonine(PKC)HMM predict
621Phosphotyrosine(INSR)HMM predict
660S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032429
  • Location:chr10 102746954-102757574
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 102746008 102746522 514 690
USF1 HepG2E 102746305 102746710 405 447
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 102761126 102761642 516 3810
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 102748304 102748833 529 0
H3K4me2 HCT116GSE10453 102750650 102751078 428 0
H3ac HepG2E 102748037 102748896 859 0
H3ac HepG2E 102750041 102751382 1341 0
PHF8 HeLaGSE20725 102748733 102750441 1708 0
RARA MCF7GSE15244 102748275 102748733 458 0
RARG MCF7GSE15244 102748339 102748733 394 0
TAF HelaGSE8489 102748454 102748790 336 0
USF1 HepG2E 102748204 102748866 662 0
USF2 HepG2E 102748231 102748833 602 0
hScc1 BcellGSE12603 102748896 102749919 1023 0
hScc1 BcellGSE12603 102755877 102756383 506 0
hScc1 G2GSE9613 102746870 102747443 573 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3576 mRNA LZTS2 chr10 102753258 102757578 22 mRNA PDZK7 chr10 102757556 102780852Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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