AutismKB 2.0

Annotation Detail for BRSK1


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Basic Information Top
Gene Symbol:BRSK1 ( FLJ43009,KIAA1811 )
Gene Full Name: BR serine/threonine kinase 1
Band: 19q13.42
Quick LinksEntrez ID:84446; OMIM: 609235; Uniprot ID:BRSK1_HUMAN; ENSEMBL ID: ENSG00000160469; HGNC ID: 18994
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
205Phosphothreonine.
209Phosphoserine (By similarity).
463Phosphoserine.
524Phosphoserine.
579Phosphoserine.
Location(AA) Modifications Resource
205Phosphothreonine.Swiss-Prot 53.0
205Phosphothreonine (LKB1)Phospho.ELM 6.0
209Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
116Phosphotyrosine(Syk)HMM predict
121Phosphotyrosine(Jak)HMM predict
123Phosphotyrosine(Jak)HMM predict
145Phosphothreonine(MAPK)HMM predict
212Phosphotyrosine(INSR)HMM predict
291Phosphoserine(CK1)HMM predict
377Phosphotyrosine(EGFR)HMM predict
429Phosphoserine(CDC2)HMM predict
433Phosphothreonine(PKC)HMM predict
448Phosphoserine(CK1)HMM predict
448PhosphoserineHMM predict
450Phosphoserine(PKB)HMM predict
450Phosphoserine(IKK)HMM predict
450O-linkedHMM predict
458O-linkedHMM predict
459Phosphoserine(IKK)HMM predict
459Phosphoserine(ATM)HMM predict
459Phosphoserine(CDC2)HMM predict
463Phosphoserine(CDC2)HMM predict
466Phosphoserine(CDC2)HMM predict
472Phosphoserine(CDC2)HMM predict
472O-linkedHMM predict
486Phosphoserine(CDC2)HMM predict
489Phosphoserine(IKK)HMM predict
489O-linkedHMM predict
489O-linkedHMM predict
493Phosphothreonine(PKC)HMM predict
500MethylarginineHMM predict
512O-linkedHMM predict
515O-linkedHMM predict
516Phosphothreonine(MAPK)HMM predict
516O-linkedHMM predict
516Phosphothreonine(CDK)HMM predict
524Phosphoserine(ATM)HMM predict
524PhosphoserineHMM predict
524O-linkedHMM predict
524Phosphoserine(CDC2)HMM predict
527O-linkedHMM predict
528O-linkedHMM predict
528O-linkedHMM predict
531Phosphothreonine(CDK)HMM predict
531Phosphothreonine(MAPK)HMM predict
539O-linkedHMM predict
539Phosphothreonine(MAPK)HMM predict
543Phosphoserine(CDC2)HMM predict
543Phosphoserine(CDK)HMM predict
545O-linkedHMM predict
547Phosphothreonine(MAPK)HMM predict
547O-linkedHMM predict
551O-linkedHMM predict
551O-linkedHMM predict
551Phosphothreonine(MAPK)HMM predict
551O-linkedHMM predict
555Phosphoserine(CDC2)HMM predict
555Phosphoserine(CDK)HMM predict
555O-linkedHMM predict
579Phosphoserine(CDC2)HMM predict
596O-linkedHMM predict
596Phosphoserine(CK1)HMM predict
599Phosphothreonine(MAPK)HMM predict
649Phosphoserine(CK1)HMM predict
653Phosphoserine(CK1)HMM predict
653Phosphoserine(IKK)HMM predict
685Phosphoserine(CK1)HMM predict
686O-linkedHMM predict
692PhosphoserineHMM predict
692O-linkedHMM predict
750Phosphothreonine(PKC)HMM predict
759O-linkedHMM predict
774Phosphoserine(CDK)HMM predict
774Phosphoserine(CDC2)HMM predict
774PhosphoserineHMM predict
779ProlineHMM predict
780ProlineHMM predict
787AlanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032430
  • Location:chr19 60487345-60515712
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 60516315 60516701 386 796
hScc1 BcellGSE12603 60517501 60517681 180 1879
hScc1 BcellGSE12603 60519842 60519985 143 4201
hScc1 BcellGSE12603 60524128 60524383 255 8543
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 60495251 60495477 226 0
CTCF CD4GSE12889 60505043 60505389 346 0
CTCF CD4SISSRdata 60495251 60495477 226 0
CTCF CD4SISSRdata 60505043 60505389 346 0
CTCF HelaGSE12889 60504923 60505374 451 0
CTCF JurkatGSE12889 60505015 60505386 371 0
CTCF G2GSE9613 60495252 60495492 240 0
CTCF G2GSE9613 60504905 60505451 546 0
ETS1 JurkatGSE17954 60507208 60507959 751 0
ETS1 JurkatGSE17954 60508204 60509459 1255 0
Myc K562GSE19551 60495128 60495482 354 0
Nanog hESGSE18292 60495219 60495603 384 0
Oct1 H2O2-HelaGSE14283 60510642 60510674 32 0
Oct1 HelaGSE14283 60495142 60495169 27 0
Oct1 HelaGSE14283 60510642 60510673 31 0
Sox2 hESGSE18292 60495249 60495430 181 0
VDR GM10861-stimGSE22484 60501205 60502492 1287 0
hScc1 BcellGSE12603 60495252 60495492 240 0
hScc1 BcellGSE12603 60505095 60505451 356 0
hScc1 BcellGSE12603 60507570 60507848 278 0
hScc1 BcellGSE12603 60514945 60515359 414 0
hScc1 CdLSGSE12603 60495252 60495492 240 0
hScc1 CdLSGSE12603 60504905 60505451 546 0
hScc1 G2GSE9613 60495252 60495492 240 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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