AutismKB 2.0

Annotation Detail for SLX4


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Basic Information Top
Gene Symbol:SLX4 ( BTBD12,KIAA1784,KIAA1987,MUS312 )
Gene Full Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Band: 16p13.3
Quick LinksEntrez ID:84464; OMIM: 613278; Uniprot ID:SLX4_HUMAN; ENSEMBL ID: ENSG00000188827; HGNC ID: 23845
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
287Phosphoserine.
1044Phosphoserine.
1315Phosphothreonine (By similarity).
1452Phosphoserine.
1469Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032444
  • Location:chr16 3571183-3601585
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 3601733 3602217 484 390
GABP k562GSE8489 3602726 3602966 240 1261
H3K4me3 colorectalcancer 3601875 3602217 342 461
H3K4me3 colorectalcancer 3602726 3602966 240 1261
H3ac HepG2E 3601733 3602217 484 390
H3ac HepG2E 3603497 3603711 214 2019
PHF8 293TGSE20725 3601009 3602313 1304 76
TAF HelaGSE8489 3602726 3602966 240 1261
hScc1 BcellGSE12603 3601345 3601957 612 66
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3582021 3582190 169 0
CTCF G2GSE9613 3584581 3585584 1003 0
CTCF G2GSE9613 3601164 3601570 406 0
ETS1 JurkatGSE17954 3600963 3602157 1194 0
H3K4me3 colorectalcancer 3600354 3600983 629 0
H3ac HepG2E 3599752 3601272 1520 0
NRSF pAbJurkat 3572073 3572540 467 0
hScc1 BcellGSE12603 3582021 3582190 169 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018