AutismKB 2.0

Annotation Detail for MCM8


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Basic Information Top
Gene Symbol:MCM8 ( C20orf154,MGC119522,MGC119523,MGC12866,MGC4816,REC,dJ967N21.5 )
Gene Full Name: minichromosome maintenance complex component 8
Band: 20p12.3
Quick LinksEntrez ID:84515; OMIM: 608187; Uniprot ID:MCM8_HUMAN; ENSEMBL ID: ENSG00000125885; HGNC ID: 16147
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
12MethylarginineHMM predict
52Phosphothreonine(MAPK)HMM predict
61Phosphothreonine(CDC2)HMM predict
64Phosphoserine(IKK)HMM predict
87Phosphoserine(CK1)HMM predict
120Phosphoserine(PKG)HMM predict
280Phosphoserine(CDC2)HMM predict
338Phosphoserine(PKG)HMM predict
372PhosphoserineHMM predict
435Phosphotyrosine(Syk)HMM predict
480N-linkedHMM predict
481O-linkedHMM predict
483O-linkedHMM predict
485O-linkedHMM predict
572Phosphothreonine(PKC)HMM predict
630Phosphoserine(ATM)HMM predict
636Phosphoserine(CK1)HMM predict
683Phosphothreonine(PKC)HMM predict
693Phosphotyrosine(Jak)HMM predict
704N-linkedHMM predict
706Phosphoserine(CDC2)HMM predict
733Phosphothreonine(CK2)HMM predict
764Phosphoserine(ATM)HMM predict
772N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032485
  • Location:chr20 5879297-5923828
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 5878948 5879551 603 48
Myc K562GSE19551 5878884 5879627 743 42
hScc1 BcellGSE12603 5878925 5879556 631 57
p130 shRbQuiescentGSE19898 5878854 5879679 825 31
p130 shRbSenescentGSE19898 5878794 5879756 962 23
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 5879106 5879997 891 0
ETS1 JurkatGSE17954 5878648 5880097 1449 0
H3K4me3 colorectalcancer 5879496 5879704 208 0
H3ac HepG2E 5879528 5881318 1790 0
LIN9 G0GSE7516 5878750 5880074 1324 0
LIN9 SGSE7516 5878781 5879997 1216 0
Nanog ESGSE20650 5898098 5898668 570 0
PHF8 HeLaGSE20725 5878821 5879955 1134 0
Rb SenescentGSE19898 5879167 5879707 540 0
Sox2 hESGSE18292 5898207 5898533 326 0
TFAP2C MCF7GSE21234 5879155 5879738 583 0
USF1 HepG2E 5879421 5880074 653 0
p130 QuiescentGSE19898 5879035 5879763 728 0
p130 SenescentGSE19898 5879163 5879614 451 0
p130 G0GSE7516 5878750 5880038 1288 0
p130 SGSE7516 5878819 5879804 985 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
16046 mRNA MCM8 chr20 5879297 5923829 4241 mRNA chr20 5919588 5934467 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018