Annotation Detail for DCTN5

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Basic Information Top

Gene Symbol:	DCTN5 ( MGC3248,p25 )
Gene Full Name:	dynactin 5 (p25)
Band:	16p12.2
Quick Links	Entrez ID:84516; OMIM: 612962; Uniprot ID:DCTN5_HUMAN; ENSEMBL ID: ENSG00000166847; HGNC ID: 24594
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:4 results

No data

Location(AA)	Modification	Resource
9	N-linked	HMM predict
13	Phosphotyrosine(EGFR)	HMM predict
13	Phosphotyrosine(INSR)	HMM predict
173	Phosphotyrosine(EGFR)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_032486
Location:chr16 23560307-23588682
strand:+

Upstream the gene:6 results
Downstream the gene:0 results
Inside the gene:12 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	23559452	23561052	1600	56
HIF1	Norm	HepG2	23559851	23560721	870	22
Rb	Growing	GSE19898	23560035	23560522	487	29
Rb	Senescent	GSE19898	23559934	23560613	679	34
p130	Quiescent	GSE19898	23559932	23560567	635	58
p130	shRbSenescent	GSE19898	23559858	23560658	800	50

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
GABP	k562	GSE8489	23561056	23561274	218	0
GABP	k562	GSE8489	23561625	23561928	303	0
H3K4me3	colorectal	cancer	23560321	23560721	400	0
H3ac	HepG2	E	23561056	23561274	218	0
PHF8	293T	GSE20725	23559667	23560995	1328	0
Rb	Quiescent	GSE19898	23560392	23560635	243	0
Stat6	IL-4-hr4	GSE17850	23560178	23560760	582	0
p130	Quiescent	GSE19898	23560592	23560782	190	0
p130	Quiescent	GSE19898	23587425	23587641	216	0
p130	shRbQuiescent	GSE19898	23560207	23560655	448	0
p130	shRbQuiescent	GSE19898	23560883	23561331	448	0
p130	shRbQuiescent	GSE19898	23587271	23587653	382	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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