AutismKB 2.0

Annotation Detail for TTBK1


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Basic Information Top
Gene Symbol:TTBK1 ( BDTK,KIAA1855,RP3-330M21.4 )
Gene Full Name: tau tubulin kinase 1
Band: 6p21.1
Quick LinksEntrez ID:84630; OMIM: NA; Uniprot ID:TTBK1_HUMAN; ENSEMBL ID: ENSG00000146216; HGNC ID: 19140
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
96S-palmitoylHMM predict
104Phosphotyrosine(INSR)HMM predict
185N-linkedHMM predict
320O-linkedHMM predict
321O-linkedHMM predict
322O-linkedHMM predict
323O-linkedHMM predict
325Phosphothreonine(CDK)HMM predict
342N-linkedHMM predict
344Phosphothreonine(CDC2)HMM predict
365Phosphoserine(ATM)HMM predict
433Phosphoserine(CDC2)HMM predict
441Phosphoserine(CDC2)HMM predict
441Phosphoserine(IKK)HMM predict
444Phosphothreonine(CDC2)HMM predict
444Phosphothreonine(MAPK)HMM predict
444Phosphothreonine(CDK)HMM predict
448Phosphoserine(PKA)HMM predict
456Phosphoserine(CDC2)HMM predict
456PhosphoserineHMM predict
483Phosphoserine(CDC2)HMM predict
483Phosphoserine(CDK)HMM predict
491Phosphoserine(ATM)HMM predict
491Phosphoserine(IKK)HMM predict
540Phosphoserine(CK1)HMM predict
562O-linkedHMM predict
564O-linkedHMM predict
564Phosphoserine(CK1)HMM predict
566O-linkedHMM predict
592Phosphothreonine(PKC)HMM predict
629Phosphothreonine(PKC)HMM predict
630O-linkedHMM predict
630Phosphoserine(ATM)HMM predict
630Phosphoserine(IKK)HMM predict
634O-linkedHMM predict
634Phosphothreonine(CDC2)HMM predict
634Phosphothreonine(MAPK)HMM predict
637Phosphoserine(CDC2)HMM predict
637Phosphoserine(IKK)HMM predict
637PhosphoserineHMM predict
639O-linkedHMM predict
641Phosphoserine(CDK)HMM predict
641Phosphoserine(ATM)HMM predict
641PhosphoserineHMM predict
654Phosphoserine(PKA)HMM predict
654Phosphoserine(PKG)HMM predict
788Phosphoserine(CK1)HMM predict
788Phosphoserine(IKK)HMM predict
821Phosphoserine(PKG)HMM predict
833Phosphoserine(CK1)HMM predict
847Phosphoserine(CDC2)HMM predict
866Phosphothreonine(MAPK)HMM predict
919O-linkedHMM predict
920O-linkedHMM predict
921Phosphoserine(CDC2)HMM predict
1005Phosphothreonine(MAPK)HMM predict
1007O-linkedHMM predict
1028Phosphoserine(CDC2)HMM predict
1028Phosphoserine(CDK)HMM predict
1028Phosphoserine(IKK)HMM predict
1033Phosphoserine(CDC2)HMM predict
1039O-linkedHMM predict
1054PhosphoserineHMM predict
1065Phosphothreonine(CK2)HMM predict
1067Phosphoserine(CK1)HMM predict
1067Phosphoserine(IKK)HMM predict
1107Phosphoserine(CAMK2)HMM predict
1112Phosphoserine(CK2)HMM predict
1113Phosphoserine(CK1)HMM predict
1113Phosphoserine(CK2)HMM predict
1114Phosphoserine(CK1)HMM predict
1121Phosphoserine(PKA)HMM predict
1121Phosphoserine(CK2)HMM predict
1121Phosphoserine(PKB)HMM predict
1125Phosphoserine(CK1)HMM predict
1125Phosphoserine(IKK)HMM predict
1133O-linkedHMM predict
1133Phosphothreonine(CDC2)HMM predict
1133Phosphothreonine(MAPK)HMM predict
1152Phosphothreonine(PKC)HMM predict
1196Phosphothreonine(MAPK)HMM predict
1196PhosphothreonineHMM predict
1214MethylarginineHMM predict
1232Phosphoserine(CDK)HMM predict
1244N-linkedHMM predict
1248Phosphoserine(CDC2)HMM predict
1248Phosphoserine(MAPK)HMM predict
1251Phosphoserine(ATM)HMM predict
1251Phosphoserine(IKK)HMM predict
1259Phosphoserine(PKG)HMM predict
1259Phosphoserine(CDC2)HMM predict
1259Phosphoserine(IKK)HMM predict
1259Phosphoserine(PKB)HMM predict
1259PhosphoserineHMM predict
1261O-linkedHMM predict
1261Phosphoserine(CDC2)HMM predict
1261Phosphoserine(CDK)HMM predict
1274MethylarginineHMM predict
1286O-linkedHMM predict
1288O-linkedHMM predict
1288Phosphoserine(CDC2)HMM predict
1288Phosphoserine(CDK)HMM predict
1307Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032538
  • Location:chr6 43319199-43363974
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 43313706 43314156 450 5269
NRSF mAbJurkat 43313270 43313522 252 5804
NRSF-mono JurkatQuESTdata 43313752 43314155 403 5246
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 43339216 43339594 378 0
CTCF CD4SISSRdata 43339216 43339594 378 0
CTCF JurkatGSE12889 43339148 43339450 302 0
CTCF G2GSE9613 43319061 43319978 917 0
CTCF G2GSE9613 43322163 43322560 397 0
CTCF G2GSE9613 43322845 43323240 395 0
CTCF G2GSE9613 43329241 43329806 565 0
CTCF G2GSE9613 43330337 43330852 515 0
CTCF G2GSE9613 43331090 43331504 414 0
CTCF G2GSE9613 43332661 43332939 278 0
CTCF G2GSE9613 43333645 43334041 396 0
CTCF G2GSE9613 43335007 43335292 285 0
CTCF G2GSE9613 43336558 43336764 206 0
CTCF G2GSE9613 43338459 43339796 1337 0
CTCF G2GSE9613 43340176 43340879 703 0
CTCF G2GSE9613 43342775 43343611 836 0
CTCF G2GSE9613 43345364 43345772 408 0
CTCF G2GSE9613 43350736 43351419 683 0
CTCF G2GSE9613 43353314 43353685 371 0
CTCF G2GSE9613 43355048 43355364 316 0
CTCF G2GSE9613 43357691 43358238 547 0
CTCF G2GSE9613 43358878 43360130 1252 0
CTCF G2GSE9613 43360655 43361365 710 0
CTCF G2GSE9613 43361623 43361896 273 0
CTCF G2GSE9613 43362280 43363579 1299 0
ER E2-MCF7GSE14664 43351404 43351441 37 0
ER MCF7GSE19013 43343323 43343742 419 0
ETS1 JurkatGSE17954 43322346 43323682 1336 0
H3K27me3 colorectalcancer 43326564 43327113 549 0
H3K27me3 colorectalcancer 43327525 43328027 502 0
H3K27me3 colorectalcancer 43328364 43329080 716 0
H3ac HepG2E 43323240 43323899 659 0
H3ac HepG2E 43340393 43340842 449 0
H3ac HepG2E 43341317 43342075 758 0
H3ac HepG2E 43342775 43343317 542 0
H3ac HepG2E 43348508 43350645 2137 0
H3ac HepG2E 43351733 43353773 2040 0
H3ac HepG2E 43355217 43356773 1556 0
H3ac HepG2E 43357120 43357260 140 0
Oct1 HelaGSE14283 43322093 43322121 28 0
P300 T30-glioblastomaGSE21026 43322765 43323303 538 0
TFAP2C MCF7GSE21234 43337731 43338321 590 0
USF1 HepG2E 43342814 43344434 1620 0
USF2 HepG2E 43342814 43344292 1478 0
USF2 HepG2E 43351895 43353494 1599 0
hScc1 BcellGSE12603 43319061 43319746 685 0
hScc1 BcellGSE12603 43321504 43321912 408 0
hScc1 BcellGSE12603 43326815 43327390 575 0
hScc1 BcellGSE12603 43332844 43333158 314 0
hScc1 BcellGSE12603 43335007 43335367 360 0
hScc1 BcellGSE12603 43338713 43339772 1059 0
hScc1 BcellGSE12603 43341095 43341317 222 0
hScc1 BcellGSE12603 43350810 43351458 648 0
hScc1 BcellGSE12603 43357691 43358164 473 0
hScc1 BcellGSE12603 43359816 43360168 352 0
hScc1 BcellGSE12603 43360586 43361650 1064 0
hScc1 BcellGSE12603 43362441 43363136 695 0
hScc1 CdLSGSE12603 43339096 43339796 700 0
hScc1 G2GSE9613 43338635 43339796 1161 0
hScc1 G2GSE9613 43350367 43351492 1125 0
p130 QuiescentGSE19898 43354312 43354596 284 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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