AutismKB 2.0

Annotation Detail for CARD6


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Basic Information Top
Gene Symbol:CARD6 ( CINCIN1 )
Gene Full Name: caspase recruitment domain family, member 6
Band: 5p13.1
Quick LinksEntrez ID:84674; OMIM: 609986; Uniprot ID:CARD6_HUMAN; ENSEMBL ID: ENSG00000132357; HGNC ID: 16394
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
468Phosphoserine.
Location(AA) Modifications Resource
468Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphothreonine(MAPK)HMM predict
28Phosphoserine(IKK)HMM predict
40Phosphoserine(PKG)HMM predict
44Phosphotyrosine(Syk)HMM predict
44Phosphotyrosine(SRC)HMM predict
44Phosphotyrosine(EGFR)HMM predict
44Phosphotyrosine(INSR)HMM predict
49N-linkedHMM predict
112Phosphoserine(CK2)HMM predict
119Phosphoserine(ATM)HMM predict
169Phosphotyrosine(EGFR)HMM predict
169Phosphotyrosine(Syk)HMM predict
169Phosphotyrosine(Abl)HMM predict
169Phosphotyrosine(SRC)HMM predict
169Phosphotyrosine(INSR)HMM predict
200Phosphotyrosine(Syk)HMM predict
233Phosphotyrosine(Abl)HMM predict
233Phosphotyrosine(INSR)HMM predict
233Phosphotyrosine(Syk)HMM predict
233PhosphotyrosineHMM predict
233SulfotyrosineHMM predict
233Phosphotyrosine(EGFR)HMM predict
233Phosphotyrosine(SRC)HMM predict
241SulfotyrosineHMM predict
250Phosphoserine(CK2)HMM predict
262Phosphotyrosine(EGFR)HMM predict
262SulfotyrosineHMM predict
270Phosphoserine(CK1)HMM predict
318Phosphothreonine(CDC2)HMM predict
354Phosphoserine(CK1)HMM predict
399Phosphotyrosine(Jak)HMM predict
476Phosphoserine(CDC2)HMM predict
590Phosphoserine(CK1)HMM predict
590PhosphoserineHMM predict
590Phosphoserine(CK2)HMM predict
642Phosphoserine(IKK)HMM predict
688Phosphoserine(ATM)HMM predict
692Phosphoserine(CDC2)HMM predict
694Phosphoserine(CK1)HMM predict
696Phosphoserine(ATM)HMM predict
696Phosphoserine(IKK)HMM predict
759Phosphoserine(CDK)HMM predict
795Phosphoserine(CDK)HMM predict
812N-linkedHMM predict
854Phosphoserine(CAMK2)HMM predict
876Phosphothreonine(PKA)HMM predict
947Phosphoserine(IKK)HMM predict
948N-linkedHMM predict
951Phosphothreonine(PKC)HMM predict
955Phosphoserine(ATM)HMM predict
955Phosphoserine(PKG)HMM predict
955Phosphoserine(IKK)HMM predict
965Phosphoserine(ATM)HMM predict
970Phosphoserine(ATM)HMM predict
974Phosphoserine(IKK)HMM predict
977PhosphoserineHMM predict
977Phosphoserine(CK1)HMM predict
977Phosphoserine(IKK)HMM predict
980Phosphoserine(ATM)HMM predict
982Phosphothreonine(PKC)HMM predict
985Phosphoserine(CDC2)HMM predict
995Phosphoserine(ATM)HMM predict
995O-linkedHMM predict
1005Phosphoserine(ATM)HMM predict
1005O-linkedHMM predict
1014Phosphoserine(IKK)HMM predict
1015O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032587
  • Location:chr5 40877166-40891210
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF HelaGSE8489 40876827 40877512 685 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018