AutismKB 2.0

Annotation Detail for SORBS2


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Basic Information Top
Gene Symbol:SORBS2 ( ARGBP2,FLJ93447,KIAA0777,PRO0618 )
Gene Full Name: sorbin and SH3 domain containing 2
Band: 4q35.1
Quick LinksEntrez ID:8470; OMIM: NA; Uniprot ID:SRBS2_HUMAN; ENSEMBL ID: ENSG00000154556; HGNC ID: 24098
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
30Phosphoserine (By similarity).
154Phosphoserine (By similarity).
157Phosphoserine.
259Phosphoserine.
277Phosphothreonine.
278Phosphoserine (By similarity).
298Phosphoserine (By similarity).
299Phosphoserine.
301Phosphoserine.
302Phosphoserine.
371Phosphothreonine (By similarity).
376Phosphoserine (By similarity).
750Phosphoserine (By similarity).
1017Phosphoserine (By similarity).
1018Phosphoserine (By similarity).
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003603
  • Location:chr4 186743592-186970385
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 186728525 186728710 185 14975
CTCF G2GSE9613 186731857 186732307 450 11511
Fos K562GSE19551 186731914 186732463 549 11404
P300 T0-glioblastomaGSE21026 186731775 186732471 696 11470
P300 T30-glioblastomaGSE21026 186731658 186732530 872 11499
TFAP2C MCF7GSE21234 186731977 186732276 299 11466
hScc1 BcellGSE12603 186731821 186732240 419 11562
p130 shRbQuiescentGSE19898 186725212 186725624 412 18175
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 186755783 186756045 262 0
CTCF CD4SISSRdata 186755783 186756045 262 0
CTCF G2GSE9613 186745468 186745775 307 0
CTCF G2GSE9613 186755793 186756136 343 0
CTCF G2GSE9613 186757921 186758441 520 0
CTCF G2GSE9613 186796435 186796873 438 0
CTCF G2GSE9613 186823839 186824124 285 0
ER MCF7GSE19013 186795304 186796434 1130 0
H3ac HepG2E 186869730 186870144 414 0
H3ac HepG2E 186871021 186871469 448 0
H3ac HepG2E 186878445 186878647 202 0
H3ac HepG2E 186967167 186968480 1313 0
H3ac HepG2E 186969068 186970125 1057 0
P300 T0-glioblastomaGSE21026 186749617 186750518 901 0
P300 T30-glioblastomaGSE21026 186749682 186750414 732 0
TAF HelaGSE8489 186805990 186806229 239 0
TFAP2C MCF7GSE21234 186900751 186901367 616 0
USF1 HepG2E 186899915 186900231 316 0
USF2 HepG2E 186869444 186870144 700 0
hScc1 BcellGSE12603 186745638 186746141 503 0
hScc1 BcellGSE12603 186755684 186756279 595 0
hScc1 BcellGSE12603 186764807 186765048 241 0
hScc1 BcellGSE12603 186823990 186824273 283 0
hScc1 CdLSGSE12603 186755309 186756426 1117 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
20535 mRNA chr4 186884211 186890304 50 mRNA ARGBP2 chr4 186883307 187108524Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018