AutismKB 2.0

Annotation Detail for LNX1


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Basic Information Top
Gene Symbol:LNX1 ( LNX,MPDZ,PDZRN2 )
Gene Full Name: ligand of numb-protein X 1
Band: 4q12
Quick LinksEntrez ID:84708; OMIM: 609732; Uniprot ID:LNX1_HUMAN; ENSEMBL ID: ENSG00000072201; HGNC ID: 6657
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
184NPXY motif.
Location(AA) Modifications Resource
Location(AA) Modification Resource
22Phosphoserine(IKK)HMM predict
29SulfotyrosineHMM predict
29Phosphotyrosine(SRC)HMM predict
64S-palmitoylHMM predict
137Phosphothreonine(PKC)HMM predict
154O-linkedHMM predict
161Phosphoserine(MAPK)HMM predict
161Phosphoserine(CDC2)HMM predict
161O-linkedHMM predict
161O-linkedHMM predict
165O-linkedHMM predict
196Phosphoserine(CDC2)HMM predict
196Phosphoserine(ATM)HMM predict
204N-linkedHMM predict
215Phosphothreonine(PKC)HMM predict
220PhosphoserineHMM predict
236Phosphoserine(PKB)HMM predict
236Phosphoserine(IKK)HMM predict
253N-linkedHMM predict
385N-linkedHMM predict
441Phosphoserine(CDC2)HMM predict
480N-linkedHMM predict
493Phosphothreonine(MAPK)HMM predict
554Phosphothreonine(PKC)HMM predict
595Phosphotyrosine(Syk)HMM predict
603Phosphoserine(IKK)HMM predict
716IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032622
  • Location:chr4 54020224-54119123
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 54136546 54137187 641 17743
FOXA1 MCF7GSE15244 54137593 54138291 698 18819
FOXA1 eGFPGSE10845 54137593 54138291 698 18819
FoxA1 MCF7MACSdata 54137586 54138058 472 18699
Oct1 HelaGSE14283 54138938 54138986 48 19839
p130 SenescentGSE19898 54119535 54119862 327 575
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 54047321 54047474 153 0
CTCF G2GSE9613 54053341 54053873 532 0
CTCF G2GSE9613 54054194 54054337 143 0
CTCF G2GSE9613 54061093 54061274 181 0
CTCF G2GSE9613 54071424 54071673 249 0
CTCF G2GSE9613 54089981 54090516 535 0
CTCF G2GSE9613 54093416 54093639 223 0
CTCF G2GSE9613 54108427 54108739 312 0
FoxA1 MCF7MACSdata 54083289 54083565 276 0
Oct1 H2O2-HelaGSE14283 54049135 54049176 41 0
Oct1 H2O2-HelaGSE14283 54111982 54112018 36 0
Oct1 HelaGSE14283 54049135 54049175 40 0
Oct1 HelaGSE14283 54111598 54111641 43 0
Oct1 HelaGSE14283 54111974 54112017 43 0
P300 T30-glioblastomaGSE21026 54037170 54037853 683 0
TFAP2C MCF7GSE21234 54058444 54058847 403 0
TFAP2C MCF7GSE21234 54083164 54083601 437 0
TFAP2C MCF7GSE21234 54098467 54098977 510 0
TFAP2C MCF7GSE21234 54115638 54116106 468 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19680 mRNA FIP1L1 chr4 54084790 54166770 374 mRNA LNX chr4 54166395 54265295Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018