AutismKB 2.0

Annotation Detail for PLEKHA8


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Basic Information Top
Gene Symbol:PLEKHA8 ( DKFZp313M1034,DKFZp686J09164,FAPP2,MGC3358 )
Gene Full Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Band: 7p14.3
Quick LinksEntrez ID:84725; OMIM: 608639; Uniprot ID:PKHA8_HUMAN; ENSEMBL ID: ENSG00000106086; HGNC ID: 30037
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032639
  • Location:chr7 30034812-30096875
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30034273 30034817 544 268
FOXA1 MCF7GSE15244 30033911 30034381 470 667
H3K4me2 HCT116GSE10453 30033837 30034381 544 704
H3ac HepG2E 30033462 30034339 877 912
TFAP2C MCF7GSE21234 30034219 30034501 282 453
hScc1 BcellGSE12603 30034273 30034740 467 306
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30098479 30098993 514 1861
ER E2-MCF7GSE14664 30106691 30106734 43 9837
Oct1 HelaGSE14283 30106989 30107027 38 10133
Oct1 HelaGSE14283 30109800 30109831 31 12940
P300 T30-glioblastomaGSE21026 30097480 30098146 666 938
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30080552 30080841 289 0
CTCF CD4SISSRdata 30080552 30080841 289 0
CTCF G2GSE9613 30068013 30068290 277 0
H3K4me3 colorectalcancer 30035330 30035830 500 0
Oct1 H2O2-HelaGSE14283 30093986 30094016 30 0
Oct1 HelaGSE14283 30036925 30036965 40 0
Oct1 HelaGSE14283 30081972 30082017 45 0
Oct1 HelaGSE14283 30093986 30094015 29 0
Sox2 hESGSE18292 30080646 30080898 252 0
hScc1 BcellGSE12603 30067935 30069094 1159 0
hScc1 CdLSGSE12603 30067935 30069094 1159 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23808 mRNA PLEKHA8 chr7 29841527 29903597 5458 EST chr7 29882513 29887971 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018