AutismKB 2.0

Annotation Detail for CDC42BPA


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Basic Information Top
Gene Symbol:CDC42BPA ( DKFZp686L1738,DKFZp686P1738,FLJ23347,KIAA0451,MRCK,MRCKA,PK428 )
Gene Full Name: CDC42 binding protein kinase alpha (DMPK-like)
Band: 1q42.13
Quick LinksEntrez ID:8476; OMIM: 603412; Uniprot ID:MRCKA_HUMAN; ENSEMBL ID: ENSG00000143776; HGNC ID: 1737
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
222Phosphoserine; by autocatalysis.
234Phosphoserine; by autocatalysis.
240Phosphothreonine; by autocatalysis.
1545Phosphoserine.
1651Phosphoserine (By similarity).
1719Phosphoserine.
1721Phosphoserine.
Location(AA) Modifications Resource
222Phosphoserine (by autocatalysis).Swiss-Prot 53.0
234Phosphoserine (by autocatalysis).Swiss-Prot 53.0
240Phosphothreonine (by autocatalysis).Swiss-Prot 53.0
Location(AA) Modification Resource
43N-linkedHMM predict
44N-linkedHMM predict
45Phosphoserine(CDC2)HMM predict
45Phosphoserine(CDK)HMM predict
151Phosphotyrosine(Syk)HMM predict
151Phosphotyrosine(INSR)HMM predict
243Phosphotyrosine(EGFR)HMM predict
243Phosphotyrosine(INSR)HMM predict
243Phosphotyrosine(Jak)HMM predict
363O-linkedHMM predict
364Phosphoserine(CDC2)HMM predict
364Phosphoserine(CDK)HMM predict
624Phosphothreonine(PKC)HMM predict
705Phosphoserine(CK1)HMM predict
750Phosphoserine(PKG)HMM predict
750PhosphoserineHMM predict
750Phosphoserine(PKC)HMM predict
752Phosphoserine(CK2)HMM predict
926Phosphoserine(CK1)HMM predict
940Phosphoserine(CK1)HMM predict
949Phosphoserine(ATM)HMM predict
972Phosphoserine(PKB)HMM predict
974Phosphothreonine(MAPK)HMM predict
974PhosphothreonineHMM predict
974Phosphothreonine(CDC2)HMM predict
982Phosphothreonine(PKC)HMM predict
986Phosphothreonine(MAPK)HMM predict
1124Phosphoserine(PKG)HMM predict
1142Phosphoserine(CK1)HMM predict
1214Phosphotyrosine(Jak)HMM predict
1220Phosphotyrosine(Syk)HMM predict
1392Phosphotyrosine(Abl)HMM predict
1433Phosphotyrosine(Jak)HMM predict
1451N-linkedHMM predict
1457Phosphotyrosine(Syk)HMM predict
1461Phosphotyrosine(Syk)HMM predict
1573N-linkedHMM predict
1576N-linkedHMM predict
1578N-linkedHMM predict
1616O-linkedHMM predict
1629Phosphoserine(PKB)HMM predict
1629Phosphoserine(IKK)HMM predict
1639O-linkedHMM predict
1639Phosphoserine(PKG)HMM predict
1642N-linkedHMM predict
1664Phosphoserine(CDC2)HMM predict
1664Phosphoserine(ATM)HMM predict
1666O-linkedHMM predict
1669Phosphoserine(IKK)HMM predict
1669Phosphoserine(CK1)HMM predict
1693Phosphoserine(ATM)HMM predict
1693PhosphoserineHMM predict
1700Phosphoserine(IKK)HMM predict
1701N-linkedHMM predict
1704N-linkedHMM predict
1707Phosphoserine(ATM)HMM predict
1707Phosphoserine(CDC2)HMM predict
1710Phosphoserine(ATM)HMM predict
1710Phosphoserine(IKK)HMM predict
1710Phosphoserine(CDC2)HMM predict
1710O-linkedHMM predict
1710Phosphoserine(CDK)HMM predict
1713Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003607
  • Location:chr1 225244189-225572448
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 225572976 225573194 218 637
Oct4 hESGSE17917 225572674 225573004 330 391
PHF8 HeLaGSE20725 225571852 225573486 1634 221
PHF8 Hs68minusFBSGSE20725 225572347 225573540 1193 495
TFAP2C MCF7GSE21234 225573239 225573838 599 1090
hScc1 G2GSE9613 225572976 225573120 144 600
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 225390082 225390395 313 0
CTCF G2GSE9613 225255382 225255824 442 0
CTCF G2GSE9613 225488876 225489656 780 0
CTCF G2GSE9613 225572208 225572650 442 0
FoxA1 MCF7MACSdata 225271475 225271628 153 0
H3K4me3 colorectalcancer 225570450 225571364 914 0
H3K4me3 colorectalcancer 225571887 225572359 472 0
H3ac HepG2E 225279590 225279837 247 0
Myc K562GSE19551 225439477 225439899 422 0
Myc K562GSE19551 225489298 225489633 335 0
NFkBII GM12878GSE19485 225249526 225250880 1354 0
NRSF JurkatGSE13047 225527884 225528284 400 0
NRSF JurkatSISSRdata 225527974 225528163 189 0
NRSF mAbJurkat 225527906 225528642 736 0
NRSF-mono JurkatQuESTdata 225527879 225528248 369 0
NRSF-poly JurkatQuESTdata 225527841 225528292 451 0
Nanog ESGSE20650 225405768 225406245 477 0
STAT1 HeLaGSE12782 225479553 225480906 1353 0
STAT1 HeLaGSE12783 225479576 225480869 1293 0
STAT1 IFNSISSRdata 225479515 225480613 1098 0
TAF k562GSE8489 225568644 225572109 3465 0
hScc1 BcellGSE12603 225249439 225249735 296 0
hScc1 BcellGSE12603 225380562 225380746 184 0
hScc1 BcellGSE12603 225489363 225489582 219 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2435 EST chr1 223486575 223487645 358 mRNA CDC42BPA chr1 223486787 223812561Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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