AutismKB 2.0

Annotation Detail for PLXDC2


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Basic Information Top
Gene Symbol:PLXDC2 ( FLJ14623,TEM7R )
Gene Full Name: plexin domain containing 2
Band: 10p12.31
Quick LinksEntrez ID:84898; OMIM: 606827; Uniprot ID:PXDC2_HUMAN; ENSEMBL ID: ENSG00000120594; HGNC ID: 21013
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
103N-linked (GlcNAc...).
160N-linked (GlcNAc...).
506Phosphoserine (By similarity).
Location(AA) Modifications Resource
103N-linked (GlcNAc...).Swiss-Prot 53.0
160N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
103N-linkedHMM predict
104N-linkedHMM predict
115Phosphotyrosine(Jak)HMM predict
116Phosphotyrosine(Jak)HMM predict
116Phosphotyrosine(Jak)HMM predict
213N-linkedHMM predict
221N-linkedHMM predict
300Phosphothreonine(PKC)HMM predict
323Phosphothreonine(MAPK)HMM predict
345N-linkedHMM predict
389O-linkedHMM predict
390O-linkedHMM predict
390O-linkedHMM predict
392O-linkedHMM predict
393O-linkedHMM predict
395O-linkedHMM predict
399O-linkedHMM predict
414Phosphothreonine(PKA)HMM predict
414Phosphothreonine(PKC)HMM predict
419O-linkedHMM predict
495Phosphoserine(PKG)HMM predict
506Phosphoserine(CK2)HMM predict
506Phosphoserine(PKG)HMM predict
511Phosphotyrosine(Abl)HMM predict
511Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032812
  • Location:chr10 20145377-20609120
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 20141046 20141088 42 4311
Oct1 HelaGSE14283 20141046 20141088 42 4311
hScc1 BcellGSE12603 20144860 20145525 665 185
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct4 hESGSE17917 20616830 20616975 145 7782
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 20181362 20181569 207 0
CBP T30-glioblastomaGSE21026 20332666 20333299 633 0
CTCF CD4GSE12889 20148395 20148754 359 0
CTCF CD4SISSRdata 20148395 20148754 359 0
ER E2-MCF7GSE14664 20149234 20149313 79 0
ER E2-MCF7GSE14664 20151108 20151145 37 0
ER E2-MCF7GSE14664 20283217 20283257 40 0
ER E2-MCF7GSE14664 20434511 20434610 99 0
ER E2-MCF7GSE14664 20530629 20530664 35 0
FoxA1 MCF7MACSdata 20260955 20261162 207 0
GABP HelaGSE8489 20164272 20164791 519 0
H3K4me3 colorectalcancer 20145560 20146285 725 0
KLF4 hESGSE17917 20586194 20586609 415 0
Nanog ESGSE20650 20544553 20545161 608 0
Nanog hESGSE18292 20444743 20445202 459 0
Oct1 H2O2-HelaGSE14283 20148312 20148338 26 0
Oct1 H2O2-HelaGSE14283 20397721 20397759 38 0
Oct1 H2O2-HelaGSE14283 20449359 20449390 31 0
Oct1 H2O2-HelaGSE14283 20567393 20567425 32 0
Oct1 HelaGSE14283 20149271 20149320 49 0
Oct1 HelaGSE14283 20249616 20249648 32 0
Oct1 HelaGSE14283 20291255 20291320 65 0
Oct1 HelaGSE14283 20294996 20295029 33 0
Oct1 HelaGSE14283 20386665 20386737 72 0
Oct1 HelaGSE14283 20397723 20397759 36 0
Oct1 HelaGSE14283 20449355 20449394 39 0
Oct1 HelaGSE14283 20451748 20451801 53 0
Oct1 HelaGSE14283 20511392 20511418 26 0
Oct1 HelaGSE14283 20530631 20530661 30 0
Oct1 HelaGSE14283 20567393 20567423 30 0
Oct4 hESGSE17917 20544823 20545071 248 0
Oct4 hESGSE21916 20447003 20447588 585 0
PAX3-FKHR Rh4GSE19063 20470858 20472035 1177 0
PAX3-FKHR Rh4GSE19063 20558201 20559023 822 0
RARA MCF7GSE15244 20176089 20176376 287 0
RARA MCF7GSE15244 20203374 20204235 861 0
RARA MCF7GSE15244 20373771 20373952 181 0
RARA MCF7GSE15244 20599975 20600919 944 0
RARG MCF7GSE15244 20145627 20146248 621 0
RARG MCF7GSE15244 20176165 20176376 211 0
RARG MCF7GSE15244 20203374 20204235 861 0
RARG MCF7GSE15244 20246812 20247610 798 0
RARG MCF7GSE15244 20599773 20600882 1109 0
TFAP2C MCF7GSE21234 20162059 20162646 587 0
TFAP2C MCF7GSE21234 20604964 20605427 463 0
p63 keratinocytesGSE17611 20161775 20162801 1026 0
p63 keratinocytesGSE17611 20387806 20388710 904 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018