AutismKB 2.0

Annotation Detail for PRSS12


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Basic Information Top
Gene Symbol:PRSS12 ( BSSP-3,BSSP3,MGC12722,MRT1 )
Gene Full Name: protease, serine, 12 (neurotrypsin, motopsin)
Band: 4q26
Quick LinksEntrez ID:8492; OMIM: 606709; Uniprot ID:NETR_HUMAN; ENSEMBL ID: ENSG00000164099; HGNC ID: 9477
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
26N-linked (GlcNAc...) (Potential).
683N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
26N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
683N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
26N-linkedHMM predict
36Phosphoserine(MAPK)HMM predict
43SulfotyrosineHMM predict
55Phosphothreonine(PKC)HMM predict
85Phosphothreonine(MAPK)HMM predict
85Phosphothreonine(CDC2)HMM predict
122Phosphoserine(ATM)HMM predict
140Phosphoserine(CDC2)HMM predict
683N-linkedHMM predict
718Phosphotyrosine(Jak)HMM predict
803Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003619
  • Location:chr4 119421864-119493369
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 119493482 119493825 343 284
CTCF CD4SISSRdata 119493482 119493825 343 284
Nanog hESGSE18292 119503103 119503520 417 9942
hScc1 CdLSGSE12603 119493331 119493844 513 218
hScc1 G2GSE9613 119492958 119493948 990 84
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 119411021 119411479 458 10615
CTCF CD4GSE12889 119421591 119421861 270 139
CTCF CD4SISSRdata 119411021 119411479 458 10615
CTCF CD4SISSRdata 119421591 119421861 270 139
CTCF G2GSE9613 119411030 119411187 157 10756
CTCF G2GSE9613 119419383 119419892 509 2227
H3ac HepG2E 119419220 119421772 2552 1369
PHF8 Hs68minusFBSGSE20725 119418892 119420109 1217 2364
PHF8 Hs68plusFBSGSE20725 119418738 119420123 1385 2434
PolII HeLaGSE12783 119417945 119424933 6988 426
TAF HelaGSE8489 119419267 119420880 1613 1791
TAF k562GSE8489 119419462 119421340 1878 1464
USF1 HepG2E 119419308 119420110 802 2156
USF2 HepG2E 119419343 119420441 1098 1973
hScc1 BcellGSE12603 119421551 119421922 371 128
hScc1 CdLSGSE12603 119421407 119422030 623 146
p130 SenescentGSE19898 119419254 119419751 497 2362
p130 shRbQuiescentGSE19898 119419068 119419950 882 2356
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 119478093 119478298 205 0
CTCF G2GSE9613 119492389 119494065 1676 0
ER Fulvestrant-MCF7GSE14664 119469046 119469086 40 0
Oct1 HelaGSE14283 119451727 119451771 44 0
hScc1 BcellGSE12603 119492569 119493877 1308 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018