AutismKB 2.0

Annotation Detail for PPFIBP2


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Basic Information Top
Gene Symbol:PPFIBP2 ( Cclp1,DKFZp781K06126,MGC42541 )
Gene Full Name: PTPRF interacting protein, binding protein 2 (liprin beta 2)
Band: 11p15.4
Quick LinksEntrez ID:8495; OMIM: 603142; Uniprot ID:LIPB2_HUMAN; ENSEMBL ID: ENSG00000166387; HGNC ID: 9250
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
329Phosphoserine (By similarity).
385Phosphoserine (By similarity).
512Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
40Phosphoserine(MAPK)HMM predict
44Phosphotyrosine(INSR)HMM predict
94Phosphoserine(CK1)HMM predict
94Phosphoserine(ATM)HMM predict
104N-linkedHMM predict
107Phosphotyrosine(Syk)HMM predict
169Phosphoserine(CK1)HMM predict
259Phosphoserine(IKK)HMM predict
329Phosphoserine(CK1)HMM predict
329Phosphoserine(PKG)HMM predict
343N-linkedHMM predict
346N-linkedHMM predict
362O-linkedHMM predict
363Phosphoserine(CDK)HMM predict
363Phosphoserine(CDC2)HMM predict
365O-linkedHMM predict
393Phosphoserine(CK1)HMM predict
424Phosphothreonine(PKC)HMM predict
430Phosphoserine(PKG)HMM predict
433Phosphothreonine(CDC2)HMM predict
475Phosphoserine(CK2)HMM predict
475Phosphoserine(CK1)HMM predict
476Phosphoserine(CK1)HMM predict
479Phosphoserine(IKK)HMM predict
479Phosphoserine(CK1)HMM predict
483Phosphoserine(IKK)HMM predict
483Phosphoserine(ATM)HMM predict
483O-linkedHMM predict
487Phosphoserine(IKK)HMM predict
487Phosphoserine(CDK)HMM predict
487Phosphoserine(CDC2)HMM predict
490Phosphothreonine(CDC2)HMM predict
510Phosphothreonine(PKA)HMM predict
544Phosphoserine(PKC)HMM predict
621Phosphothreonine(CK2)HMM predict
708Phosphoserine(IKK)HMM predict
709N-linkedHMM predict
711Phosphoserine(CDC2)HMM predict
803Phosphothreonine(CDK)HMM predict
803Phosphothreonine(MAPK)HMM predict
806O-linkedHMM predict
807O-linkedHMM predict
835Phosphotyrosine(EGFR)HMM predict
835Phosphotyrosine(INSR)HMM predict
835Phosphotyrosine(Jak)HMM predict
835SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003621
  • Location:chr11 7491628-7631557
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 7490907 7492158 1251 96
VDR GM10855-stimGSE22484 7489081 7492903 3822 637
VDR GM10861-stimGSE22484 7488878 7492452 3574 964
hScc1 BcellGSE12603 7490383 7491495 1112 690
hScc1 CdLSGSE12603 7490342 7491659 1317 628
hScc1 G2GSE9613 7490730 7491838 1108 345
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 7635299 7635426 127 3805
CTCF CD4SISSRdata 7635299 7635426 127 3805
hScc1 CdLSGSE12603 7634725 7635363 638 3487
hScc1 G2GSE9613 7634791 7635687 896 3682
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 7584531 7584892 361 0
CTCF CD4GSE12889 7514070 7514191 121 0
CTCF CD4SISSRdata 7514070 7514191 121 0
CTCF JurkatGSE12889 7514059 7514210 151 0
ER E2-MCF7GSE14664 7622284 7622320 36 0
FOXA1 DLD1GSE12801 7550014 7550545 531 0
FOXA1 DLD1GSE12801 7583168 7583888 720 0
FOXA1 DLD1GSE12801 7589133 7589604 471 0
FOXA1 DLD1GSE12801 7590459 7590875 416 0
FOXA1 MCF7GSE15244 7516100 7517147 1047 0
FOXA1 MCF7GSE15244 7518651 7519206 555 0
FOXA1 MCF7GSE15244 7549902 7550545 643 0
FOXA1 MCF7GSE15244 7574941 7575601 660 0
FOXA1 MCF7GSE15244 7577778 7578463 685 0
FOXA1 MCF7GSE15244 7581953 7582799 846 0
FOXA1 MCF7GSE15244 7583168 7583998 830 0
FOXA1 MCF7GSE15244 7588891 7589604 713 0
FOXA1 MCF7GSE15244 7590352 7590846 494 0
FOXA1 MCF7GSE15244 7591302 7591597 295 0
FoxA1 MCF7MACSdata 7589093 7589241 148 0
GATA3 MCF7GSE15244 7588891 7589811 920 0
Gata2 K562GSE18868 7628891 7629417 526 0
H3ac HepG2E 7552480 7553601 1121 0
H3ac HepG2E 7554744 7555898 1154 0
KLF4 hESGSE17917 7540986 7541380 394 0
NFkBII GM10847GSE19485 7508448 7509581 1133 0
NFkBII GM12878GSE19485 7508293 7509639 1346 0
NFkBII GM18526GSE19485 7508318 7509465 1147 0
NRSF pAbJurkat 7553639 7554558 919 0
Oct1 H2O2-HelaGSE14283 7527892 7527926 34 0
Oct1 H2O2-HelaGSE14283 7574448 7574483 35 0
Oct1 HelaGSE14283 7527891 7527926 35 0
Oct1 HelaGSE14283 7574438 7574483 45 0
P300 T30-glioblastomaGSE21026 7549265 7550617 1352 0
P300 T30-glioblastomaGSE21026 7570577 7570953 376 0
PAX3-FKHR Rh4GSE19063 7583928 7584953 1025 0
RARA MCF7GSE15244 7516344 7516861 517 0
RARA MCF7GSE15244 7518651 7519280 629 0
RARA MCF7GSE15244 7577778 7578502 724 0
RARA MCF7GSE15244 7581916 7583923 2007 0
RARA MCF7GSE15244 7588891 7589811 920 0
RARA MCF7GSE15244 7590423 7590809 386 0
RARG MCF7GSE15244 7515991 7516714 723 0
RARG MCF7GSE15244 7518651 7519242 591 0
RARG MCF7GSE15244 7550049 7550545 496 0
RARG MCF7GSE15244 7553244 7553674 430 0
RARG MCF7GSE15244 7577778 7578502 724 0
RARG MCF7GSE15244 7581916 7583847 1931 0
RUNX JurkatGSE17954 7553933 7554105 172 0
STAT1 HeLaGSE12783 7550996 7554537 3541 0
TFAP2C MCF7GSE21234 7518579 7519093 514 0
TFAP2C MCF7GSE21234 7526561 7527152 591 0
TFAP2C MCF7GSE21234 7549865 7550539 674 0
TFAP2C MCF7GSE21234 7565268 7565596 328 0
TFAP2C MCF7GSE21234 7575402 7575856 454 0
TFAP2C MCF7GSE21234 7577936 7578792 856 0
TFAP2C MCF7GSE21234 7582122 7582785 663 0
TFAP2C MCF7GSE21234 7590394 7591122 728 0
USF1 HepG2E 7493960 7494269 309 0
USF1 HepG2E 7551424 7553601 2177 0
USF2 HepG2E 7548374 7548721 347 0
USF2 HepG2E 7552409 7553601 1192 0
VDR GM10855-stimGSE22484 7519689 7521352 1663 0
VDR GM10861-stimGSE22484 7519946 7521269 1323 0
hScc1 BcellGSE12603 7526697 7527262 565 0
hScc1 BcellGSE12603 7549515 7549902 387 0
hScc1 CdLSGSE12603 7526664 7527262 598 0
hScc1 CdLSGSE12603 7549446 7550014 568 0
hScc1 G2GSE9613 7526760 7527220 460 0
hScc1 G2GSE9613 7549479 7550092 613 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 19586368
hsa-miR-1 hsa-mir-1-1 20 19586368
hsa-miR-133a hsa-mir-133a-1 18 19586368
hsa-miR-133a hsa-mir-133a-2 20 19586368
hsa-miR-133b hsa-mir-133b 6 19586368
hsa-miR-206 hsa-mir-206 6 19586368
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4082 mRNA PPFIBP2 chr11 7491628 7631558 2669 mRNA chr11 7492584 7495253 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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