AutismKB 2.0

Annotation Detail for FBXL20


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Basic Information Top
Gene Symbol:FBXL20 ( DKFZp564O2364,FLJ21037,Fbl2,Fbl20,MGC15482 )
Gene Full Name: F-box and leucine-rich repeat protein 20
Band: 17q12
Quick LinksEntrez ID:84961; OMIM: 609086; Uniprot ID:FXL20_HUMAN; ENSEMBL ID: ENSG00000108306; HGNC ID: 24679
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
417Phosphothreonine.
421Phosphoserine (By similarity).
Location(AA) Modifications Resource
417Phosphothreonine (By similarity).Swiss-Prot 53.0
421Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
130O-linkedHMM predict
134O-linkedHMM predict
155Phosphoserine(IKK)HMM predict
175N-linkedHMM predict
243S-palmitoylHMM predict
246S-palmitoylHMM predict
255Phosphoserine(IKK)HMM predict
259N-linkedHMM predict
380Phosphoserine(CK1)HMM predict
417Phosphothreonine(MAPK)HMM predict
417PhosphothreonineHMM predict
417O-linkedHMM predict
421O-linkedHMM predict
429PhenylalanineHMM predict
430PhenylalanineHMM predict
431PhenylalanineHMM predict
432PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032875
  • Location:chr17 34670366-34811401
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 34812268 34812922 654 1194
Fos K562GSE19551 34812233 34812835 602 1133
LIN9 G0GSE7516 34812223 34812922 699 1171
LIN9 SGSE7516 34812223 34812922 699 1171
PHF8 HeLaGSE20725 34810927 34812280 1353 202
Rb GrowingGSE19898 34812286 34812610 324 1047
Rb QuiescentGSE19898 34812341 34812687 346 1113
Rb SenescentGSE19898 34812183 34812660 477 1020
Rb shRbSenescenceGSE19898 34812285 34812650 365 1066
hScc1 BcellGSE12603 34811147 34812014 867 179
p130 QuiescentGSE19898 34812263 34812992 729 1226
p130 SenescentGSE19898 34812179 34812951 772 1164
p130 shRbQuiescentGSE19898 34812093 34812999 906 1145
p130 shRbSenescentGSE19898 34811592 34811833 241 311
p130 shRbSenescentGSE19898 34812208 34812958 750 1182
p130 G0GSE7516 34811920 34812922 1002 1020
p130 SGSE7516 34812223 34812922 699 1171
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 34654499 34654808 309 15713
CTCF CD4SISSRdata 34654499 34654808 309 15713
CTCF G2GSE9613 34654455 34654954 499 15662
ER E2-MCF7GSE14664 34666145 34666178 33 4205
ER E2-MCF7GSE14664 34667806 34667864 58 2532
ER Fulvestrant-MCF7GSE14664 34666145 34666179 34 4205
ER Fulvestrant-MCF7GSE14664 34667819 34667870 51 2522
FoxA1 MCF7MACSdata 34658260 34658447 187 12013
Oct1 H2O2-HelaGSE14283 34664848 34664886 38 5500
Oct1 HelaGSE14283 34664849 34664893 44 5496
Oct1 HelaGSE14283 34666145 34666182 37 4203
hScc1 BcellGSE12603 34654381 34654811 430 15771
hScc1 CdLSGSE12603 34654420 34654845 425 15734
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 34671204 34671349 145 0
CTCF CD4SISSRdata 34671204 34671349 145 0
ER E2-MCF7GSE14664 34709047 34709102 55 0
H3K4me3 colorectalcancer 34809827 34810920 1093 0
H3ac HepG2E 34809755 34811038 1283 0
Myc K562GSE19551 34671104 34671396 292 0
Myc K562GSE19551 34735727 34736001 274 0
Nanog hESGSE18292 34690970 34691140 170 0
Oct1 H2O2-HelaGSE14283 34679359 34679386 27 0
Oct1 H2O2-HelaGSE14283 34690082 34690115 33 0
Oct1 H2O2-HelaGSE14283 34690525 34690551 26 0
Oct1 H2O2-HelaGSE14283 34736252 34736280 28 0
Oct1 H2O2-HelaGSE14283 34740196 34740223 27 0
Oct1 H2O2-HelaGSE14283 34759199 34759233 34 0
Oct1 HelaGSE14283 34678304 34678338 34 0
Oct1 HelaGSE14283 34690081 34690118 37 0
Oct1 HelaGSE14283 34692598 34692715 117 0
Oct1 HelaGSE14283 34701313 34701348 35 0
Oct1 HelaGSE14283 34736253 34736282 29 0
TAF HelaGSE8489 34809875 34810728 853 0
TAF k562GSE8489 34809281 34810728 1447 0
hScc1 CdLSGSE12603 34803541 34803903 362 0
p63 keratinocytesGSE17611 34787120 34788094 974 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018