AutismKB 2.0

Annotation Detail for TOX2


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Basic Information Top
Gene Symbol:TOX2 ( C20orf100,GCX-1,MGC15880,dJ1108D11.2,dJ495O3.1 )
Gene Full Name: TOX high mobility group box family member 2
Band: 20q13.12
Quick LinksEntrez ID:84969; OMIM: 611163; Uniprot ID:TOX2_HUMAN; ENSEMBL ID: ENSG00000124191; HGNC ID: 16095
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
252Nuclear localization signal (By
Location(AA) Modifications Resource
Location(AA) Modification Resource
49Phosphotyrosine(INSR)HMM predict
63Phosphoserine(ATM)HMM predict
76Phosphotyrosine(Syk)HMM predict
76SulfotyrosineHMM predict
82Phosphothreonine(MAPK)HMM predict
109Phosphothreonine(CDK)HMM predict
181Phosphoserine(ATM)HMM predict
183Phosphoserine(IKK)HMM predict
183Phosphoserine(ATM)HMM predict
199Phosphoserine(CDK)HMM predict
199Phosphoserine(ATM)HMM predict
199O-linkedHMM predict
201Phosphoserine(IKK)HMM predict
201O-linkedHMM predict
201Phosphoserine(CDC2)HMM predict
201Phosphoserine(ATM)HMM predict
209O-linkedHMM predict
209O-linkedHMM predict
209Phosphothreonine(MAPK)HMM predict
209O-linkedHMM predict
211Phosphoserine(IKK)HMM predict
211Phosphoserine(CDC2)HMM predict
211O-linkedHMM predict
211Phosphoserine(ATM)HMM predict
213O-linkedHMM predict
215Phosphoserine(CK2)HMM predict
215O-linkedHMM predict
277N-linkedHMM predict
303Phosphoserine(IKK)HMM predict
313Phosphothreonine(PKA)HMM predict
329Phosphotyrosine(Abl)HMM predict
351Phosphoserine(CDC2)HMM predict
369O-linkedHMM predict
371Phosphoserine(CDK)HMM predict
371O-linkedHMM predict
371Phosphoserine(IKK)HMM predict
371Phosphoserine(CDC2)HMM predict
371Phosphoserine(ATM)HMM predict
381O-linkedHMM predict
400Phosphoserine(ATM)HMM predict
400Phosphoserine(MAPK)HMM predict
406PhosphoserineHMM predict
406O-linkedHMM predict
406Phosphoserine(CDC2)HMM predict
406Phosphoserine(IKK)HMM predict
416Phosphothreonine(MAPK)HMM predict
427Phosphoserine(CDK)HMM predict
427O-linkedHMM predict
427Phosphoserine(CDC2)HMM predict
429Phosphoserine(CDC2)HMM predict
429Phosphoserine(ATM)HMM predict
445O-linkedHMM predict
446O-linkedHMM predict
450Phosphoserine(ATM)HMM predict
450Phosphoserine(MAPK)HMM predict
450Phosphoserine(CDC2)HMM predict
455N-linkedHMM predict
477SerineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032883
  • Location:chr20 41978220-42131665
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 41977121 41978310 1189 505
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 42142799 42143118 319 11293
CTCF CD4SISSRdata 42142799 42143118 319 11293
CTCF JurkatGSE12889 42142747 42143147 400 11282
CTCF G2GSE9613 42142087 42142571 484 10664
CTCF G2GSE9613 42143001 42143360 359 11515
TAFII hESGSE17917 42142880 42143088 208 11319
hScc1 BcellGSE12603 42142266 42142571 305 10753
hScc1 BcellGSE12603 42143687 42143938 251 12147
hScc1 BcellGSE12603 42149516 42149872 356 18029
hScc1 G2GSE9613 42143001 42143426 425 11548
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 42011733 42013316 1583 0
CBP T30-glioblastomaGSE21026 42016989 42018184 1195 0
CTCF CD4GSE12889 41987949 41988051 102 0
CTCF CD4GSE12889 42045533 42045657 124 0
CTCF CD4GSE12889 42118073 42118381 308 0
CTCF CD4SISSRdata 41987949 41988051 102 0
CTCF CD4SISSRdata 42045533 42045657 124 0
CTCF CD4SISSRdata 42118073 42118381 308 0
CTCF JurkatGSE12889 42118136 42118452 316 0
CTCF G2GSE9613 41998975 41999123 148 0
CTCF G2GSE9613 42006199 42006475 276 0
Gata2 K562GSE18868 42012260 42012699 439 0
Gata2 K562GSE18868 42072281 42072978 697 0
H3K27me3 colorectalcancer 41978430 41979714 1284 0
NFkBII GM12892GSE19485 41978524 41980038 1514 0
P300 T30-glioblastomaGSE21026 42016235 42018288 2053 0
RARA MCF7GSE15244 42001388 42002228 840 0
RARA MCF7GSE15244 42011841 42012448 607 0
RARA MCF7GSE15244 42017330 42017970 640 0
Rb shRbQuiescentGSE19898 42063363 42063504 141 0
Rb shRbQuiescentGSE19898 42097398 42097631 233 0
TFAP2C MCF7GSE21234 41987317 41988124 807 0
TFAP2C MCF7GSE21234 42017433 42017976 543 0
hScc1 BcellGSE12603 41983616 41983960 344 0
hScc1 BcellGSE12603 42017761 42018288 527 0
hScc1 BcellGSE12603 42045269 42045559 290 0
hScc1 BcellGSE12603 42090999 42091628 629 0
hScc1 BcellGSE12603 42118418 42118669 251 0
hScc1 BcellGSE12603 42127799 42128810 1011 0
hScc1 BcellGSE12603 42129827 42130170 343 0
p130 SenescentGSE19898 42037124 42037679 555 0
p130 shRbQuiescentGSE19898 42037235 42037696 461 0
p63 keratinocytesGSE17611 41990171 41990972 801 0
p63 keratinocytesGSE17611 42015053 42016036 983 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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