AutismKB 2.0

Annotation Detail for NDST2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NDST2 ( HSST2,MGC129697,MGC129705,NST2 )
Gene Full Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Band: 10q22.2
Quick LinksEntrez ID:8509; OMIM: 603268; Uniprot ID:NDST2_HUMAN; ENSEMBL ID: ENSG00000166507; HGNC ID: 7681
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
233N-linked (GlcNAc...) (Potential).
350N-linked (GlcNAc...) (Potential).
400N-linked (GlcNAc...) (Potential).
666N-linked (GlcNAc...) (Potential).
726N-linked (GlcNAc...) (Potential).
802N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
233N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
350N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
400N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
666N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
726N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
802N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
41Phosphoserine(CDC2)HMM predict
96Phosphoserine(IKK)HMM predict
96Phosphoserine(CK1)HMM predict
146Phosphotyrosine(INSR)HMM predict
178Phosphoserine(CK1)HMM predict
203N-linkedHMM predict
233N-linkedHMM predict
235Phosphoserine(CK1)HMM predict
237Phosphotyrosine(Syk)HMM predict
301Phosphothreonine(PKC)HMM predict
327Phosphothreonine(PKC)HMM predict
460SulfotyrosineHMM predict
630Phosphothreonine(PKC)HMM predict
630O-linkedHMM predict
632Phosphoserine(IKK)HMM predict
650Phosphotyrosine(INSR)HMM predict
710SulfotyrosineHMM predict
726N-linkedHMM predict
737Phosphoserine(ATM)HMM predict
739Phosphothreonine(MAPK)HMM predict
802N-linkedHMM predict
825PhosphothreonineHMM predict
827S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003635
  • Location:chr10 75231674-75241347
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T30-glioblastomaGSE21026 75241114 75241996 882 208
Rb GrowingGSE19898 75241512 75241724 212 271
Rb SenescentGSE19898 75241532 75241840 308 339
hScc1 BcellGSE12603 75241291 75241584 293 90
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 75238870 75239454 584 0
NFkBII GM15510GSE19485 75240614 75241871 1257 0
PHF8 HeLaGSE20725 75240615 75241746 1131 0
hScc1 CdLSGSE12603 75240660 75241820 1160 0
hScc1 G2GSE9613 75240660 75241820 1160 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3317 mRNA KIAA0913 chr10 75222494 75231556 1304 HTC NDST2 chr10 75226279 75241415Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018