AutismKB 2.0

Annotation Detail for HIST1H2BK


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Basic Information Top
Gene Symbol:HIST1H2BK ( H2B/S,H2BFAiii,H2BFT,MGC131989 )
Gene Full Name: histone cluster 1, H2bk
Band: 6p22.1
Quick LinksEntrez ID:85236; OMIM: NA; Uniprot ID:H2B1K_HUMAN; ENSEMBL ID: ENSG00000197903; HGNC ID: 13954
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
6N6-acetyllysine.
12N6-acetyllysine.
13N6-acetyllysine.
15Phosphoserine; by STK4.
16N6-acetyllysine.
17N6-acetyllysine.
21N6-acetyllysine.
24N6-acetyllysine.
47N6-methyllysine.
58N6,N6-dimethyllysine.
109N6-acetyllysine; alternate.
109N6-methyllysine; alternate.
Location(AA) Modifications Resource
6N6-acetyllysine.Swiss-Prot 53.0
12N6-acetyllysine.Swiss-Prot 53.0
13N6-acetyllysine.Swiss-Prot 53.0
15Phosphoserine (by STK4).Swiss-Prot 53.0
16N6-acetyllysine.Swiss-Prot 53.0
17N6-acetyllysine.Swiss-Prot 53.0
21N6-acetyllysine.Swiss-Prot 53.0
24N6-acetyllysine.Swiss-Prot 53.0
47N6-methyllysine.Swiss-Prot 53.0
58N6,N6-dimethyllysine.Swiss-Prot 53.0
109N6-acetyllysine; alternate.Swiss-Prot 53.0
109N6-methyllysine; alternate.Swiss-Prot 53.0
121Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
Location(AA) Modification Resource
15Phosphoserine(PKA)HMM predict
33Phosphoserine(PKA)HMM predict
33Phosphoserine(PKC)HMM predict
33Phosphoserine(PKG)HMM predict
37Phosphoserine(PKA)HMM predict
37Phosphoserine(PKC)HMM predict
37Phosphoserine(PKG)HMM predict
38Phosphotyrosine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_080593
  • Location:chr6 27214051-27222597
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 27222183 27223234 1051 111
LIN9 SGSE7516 27221976 27223341 1365 61
p130 SGSE7516 27222153 27223269 1116 114
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27221726 27221940 214 0
H3K4me2 HCT116GSE10453 27220858 27222153 1295 0
H3K4me3 colorectalcancer 27214967 27216279 1312 0
H3K4me3 colorectalcancer 27221102 27223550 2448 0
H3ac HepG2E 27222090 27222366 276 0
LIN9 G0GSE7516 27222090 27222506 416 0
PHF8 Hs68plusFBSGSE20725 27221427 27223484 2057 0
Pol2 GM12878GSE19551 27214808 27216239 1431 0
Pol2 GM12878GSE19551 27220901 27223956 3055 0
PolII HeLaGSE12783 27216712 27225246 8534 0
RARA MCF7GSE15244 27221494 27222978 1484 0
RARG MCF7GSE15244 27221419 27223091 1672 0
Rb GrowingGSE19898 27214868 27215233 365 0
Rb QuiescentGSE19898 27221580 27222230 650 0
Rb SenescentGSE19898 27214776 27215324 548 0
Rb shRbQuiescentGSE19898 27214759 27215180 421 0
Rb shRbSenescenceGSE19898 27214877 27215158 281 0
Rb shRbSenescenceGSE19898 27221692 27221991 299 0
TAF HelaGSE8489 27220858 27222940 2082 0
TAF k562GSE8489 27216734 27217632 898 0
TAF k562GSE8489 27219134 27219895 761 0
TAF k562GSE8489 27220232 27223550 3318 0
VDR GM10861-UnstimGSE22484 27220033 27224823 4790 0
VDR GM10861-stimGSE22484 27213949 27218187 4238 0
VDR GM10861-stimGSE22484 27220197 27224590 4393 0
p130 QuiescentGSE19898 27214825 27215228 403 0
p130 QuiescentGSE19898 27221586 27222129 543 0
p130 SenescentGSE19898 27214758 27215169 411 0
p130 SenescentGSE19898 27221475 27222188 713 0
p130 shRbQuiescentGSE19898 27214796 27215150 354 0
p130 shRbSenescentGSE19898 27221394 27222231 837 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22285 mRNA HIST1H4I chr6 27215066 27215436 370 mRNA HIST1H2BK chr6 27214051 27222598 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018