AutismKB 2.0

Annotation Detail for DGKZ


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Basic Information Top
Gene Symbol:DGKZ ( DAGK5,DAGK6,DGK-ZETA,hDGKzeta )
Gene Full Name: diacylglycerol kinase, zeta 104kDa
Band: 11p11.2
Quick LinksEntrez ID:8525; OMIM: 601441; Uniprot ID:DGKZ_HUMAN; ENSEMBL ID: ENSG00000149091; HGNC ID: 2857
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
558Nuclear export signal (By similarity).
686Phosphoserine.
Location(AA) Modifications Resource
686Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
24Phosphoserine(PKA)HMM predict
24Phosphoserine(PKA)HMM predict
25Phosphoserine(IKK)HMM predict
25O-linkedHMM predict
30Phosphothreonine(PKC)HMM predict
37Phosphoserine(IKK)HMM predict
37Phosphoserine(CDC2)HMM predict
37Phosphoserine(CAMK2)HMM predict
37Phosphoserine(PKG)HMM predict
37Phosphoserine(PKA)HMM predict
52Phosphoserine(PKA)HMM predict
52Phosphoserine(PKG)HMM predict
53Phosphoserine(PKA)HMM predict
53Phosphoserine(PKG)HMM predict
53Phosphoserine(PKB)HMM predict
71Phosphoserine(PKC)HMM predict
75Phosphoserine(PKG)HMM predict
75Phosphoserine(CK1)HMM predict
76Phosphoserine(PKG)HMM predict
76Phosphoserine(PKB)HMM predict
76O-linkedHMM predict
77Phosphothreonine(PKC)HMM predict
93Phosphothreonine(MAPK)HMM predict
93Phosphothreonine(CDK)HMM predict
97O-linkedHMM predict
140Phosphothreonine(CDC2)HMM predict
140Phosphothreonine(MAPK)HMM predict
147MethylarginineHMM predict
164Phosphoserine(PKA)HMM predict
188PhosphoserineHMM predict
193PhosphoserineHMM predict
193Phosphoserine(PKA)HMM predict
205Phosphoserine(PKG)HMM predict
205Phosphoserine(CAMK2)HMM predict
205O-linkedHMM predict
211O-linkedHMM predict
260O-linkedHMM predict
279Phosphoserine(IKK)HMM predict
284Phosphotyrosine(EGFR)HMM predict
293N-linkedHMM predict
376S-palmitoylHMM predict
443Phosphothreonine(PKC)HMM predict
454Phosphoserine(PKA)HMM predict
454Phosphoserine(PKC)HMM predict
460Phosphoserine(PKG)HMM predict
460Phosphoserine(PKA)HMM predict
479Phosphoserine(CDC2)HMM predict
479Phosphoserine(CDK)HMM predict
747Phosphotyrosine(EGFR)HMM predict
824O-linkedHMM predict
850SulfotyrosineHMM predict
927Phosphotyrosine(INSR)HMM predict
957Phosphoserine(IKK)HMM predict
957Phosphoserine(CDC2)HMM predict
957O-linkedHMM predict
957Phosphoserine(MAPK)HMM predict
961Phosphothreonine(PKC)HMM predict
961O-linkedHMM predict
962Phosphoserine(CDC2)HMM predict
962Phosphoserine(IKK)HMM predict
962Phosphoserine(CDK)HMM predict
965Phosphoserine(MAPK)HMM predict
967Phosphothreonine(CDK)HMM predict
967O-linkedHMM predict
967Phosphothreonine(MAPK)HMM predict
1021O-linkedHMM predict
1082Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003646
  • Location:chr11 46325594-46358679
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb QuiescentGSE19898 46358853 46358992 139 243
p130 shRbSenescentGSE19898 46358724 46359097 373 231
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46330312 46330636 324 0
CTCF CD4SISSRdata 46330312 46330636 324 0
CTCF JurkatGSE12889 46330230 46330598 368 0
ER MCF7GSE19013 46330431 46330951 520 0
ER MCF7GSE19013 46340929 46342438 1509 0
FOXA1 MCF7GSE15244 46346073 46346617 544 0
H3ac HepG2E 46326180 46326630 450 0
NRSF pAbJurkat 46345165 46345715 550 0
NRSF pAbJurkat 46355231 46355530 299 0
Oct1 HelaGSE14283 46325782 46325814 32 0
P300 T30-glioblastomaGSE21026 46347209 46347960 751 0
STAT1 IFNSISSRdata 46345551 46346282 731 0
TFAP2C MCF7GSE21234 46341755 46342246 491 0
hScc1 BcellGSE12603 46325441 46326000 559 0
hScc1 BcellGSE12603 46340825 46341028 203 0
hScc1 BcellGSE12603 46345393 46346502 1109 0
hScc1 BcellGSE12603 46347584 46347911 327 0
hScc1 BcellGSE12603 46349391 46349715 324 0
hScc1 BcellGSE12603 46353514 46353960 446 0
hScc1 BcellGSE12603 46356654 46357417 763 0
hScc1 BcellGSE12603 46357960 46358572 612 0
hScc1 CdLSGSE12603 46345595 46346400 805 0
hScc1 G2GSE9613 46344370 46344789 419 0
hScc1 G2GSE9613 46345246 46346179 933 0
p130 shRbQuiescentGSE19898 46341539 46342078 539 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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