Annotation Detail for SYDE1

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Basic Information Top

Gene Symbol:	SYDE1 ( 7h3,FLJ13511 )
Gene Full Name:	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
Band:	19p13.12
Quick Links	Entrez ID:85360; OMIM: NA; Uniprot ID:SYDE1_HUMAN; ENSEMBL ID: ENSG00000105137; HGNC ID: 25824
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:7 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
231	Phosphoserine.
235	Phosphoserine.
244	Phosphoserine.
246	Phosphothreonine.
247	Phosphoserine.
681	Phosphoserine.
683	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_033025
Location:chr19 15079213-15086788
strand:+

Upstream the gene:12 results
Downstream the gene:0 results
Inside the gene:6 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	15073263	15073563	300	5801
CTCF	CD4	SISSRdata	15073263	15073563	300	5801
PHF8	293T	GSE20725	15078460	15079827	1367	70
Rb	Growing	GSE19898	15078994	15079134	140	150
Rb	Quiescent	GSE19898	15079003	15079151	148	137
Rb	Senescent	GSE19898	15078819	15079142	323	233
Rb	shRbSenescence	GSE19898	15078847	15079094	247	243
hScc1	Bcell	GSE12603	15078904	15079272	368	126
p130	Quiescent	GSE19898	15078842	15079285	443	150
p130	Senescent	GSE19898	15078782	15079140	358	253
p130	shRbQuiescent	GSE19898	15078728	15079084	356	308
p130	shRbSenescent	GSE19898	15078716	15079140	424	286

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3K27me3	colorectal	cancer	15079761	15080713	952	0
Oct1	Hela	GSE14283	15081349	15081405	56	0
PHF8	HeLa	GSE20725	15078748	15079875	1127	0
PHF8	Hs68plusFBS	GSE20725	15078769	15080518	1749	0
Rb	Growing	GSE19898	15080388	15080538	150	0
hScc1	Bcell	GSE12603	15080743	15081035	292	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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