AutismKB 2.0

Annotation Detail for SSH2


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Basic Information Top
Gene Symbol:SSH2 ( KIAA1725,MGC78588,SSH-2 )
Gene Full Name: slingshot homolog 2 (Drosophila)
Band: 17q11.2
Quick LinksEntrez ID:85464; OMIM: 606779; Uniprot ID:SSH2_HUMAN; ENSEMBL ID: ENSG00000141298; HGNC ID: 30580
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
36Phosphoserine.
461Phosphoserine.
487Phosphoserine.
1422Phosphothreonine.
Location(AA) Modifications Resource
461Phosphoserine.Swiss-Prot 53.0
461PhosphoserinePhospho.ELM 6.0
1422Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
9O-linkedHMM predict
9Phosphoserine(CDK)HMM predict
9Phosphoserine(IKK)HMM predict
9PhosphoserineHMM predict
11Phosphothreonine(MAPK)HMM predict
11Phosphothreonine(CDK)HMM predict
13O-linkedHMM predict
13O-linkedHMM predict
13O-linkedHMM predict
14O-linkedHMM predict
15O-linkedHMM predict
15O-linkedHMM predict
15O-linkedHMM predict
16O-linkedHMM predict
17Phosphoserine(CDC2)HMM predict
17Phosphoserine(IKK)HMM predict
25Phosphoserine(CK1)HMM predict
25Phosphoserine(CK2)HMM predict
32Phosphoserine(CK1)HMM predict
32Phosphoserine(IKK)HMM predict
36Phosphoserine(IKK)HMM predict
55N-linkedHMM predict
100Phosphotyrosine(Syk)HMM predict
102N-linkedHMM predict
130Phosphoserine(IKK)HMM predict
131N-linkedHMM predict
134Phosphoserine(IKK)HMM predict
219Phosphoserine(CK1)HMM predict
269N-linkedHMM predict
307Phosphoserine(ATM)HMM predict
322N-linkedHMM predict
325N-linkedHMM predict
339N-linkedHMM predict
372N-linkedHMM predict
401O-linkedHMM predict
427Phosphothreonine(PKC)HMM predict
429Phosphothreonine(PKA)HMM predict
434Phosphoserine(PKA)HMM predict
466Phosphoserine(CK1)HMM predict
466Phosphoserine(CK2)HMM predict
466Phosphoserine(ATM)HMM predict
552N-linkedHMM predict
558S-palmitoylHMM predict
559S-palmitoylHMM predict
561N-linkedHMM predict
618Phosphoserine(CDC2)HMM predict
618Phosphoserine(MAPK)HMM predict
618Phosphoserine(CDK)HMM predict
626O-linkedHMM predict
626Phosphoserine(MAPK)HMM predict
631Phosphoserine(IKK)HMM predict
633O-linkedHMM predict
633Phosphoserine(CDC2)HMM predict
633Phosphoserine(CDK)HMM predict
663Phosphoserine(ATM)HMM predict
670Phosphoserine(IKK)HMM predict
690Phosphoserine(PKG)HMM predict
708Phosphoserine(PKA)HMM predict
708Phosphoserine(PKC)HMM predict
708Phosphoserine(CK1)HMM predict
708Phosphoserine(IKK)HMM predict
708Phosphoserine(PKB)HMM predict
708PhosphoserineHMM predict
712Phosphothreonine(MAPK)HMM predict
719Phosphoserine(CK2)HMM predict
720Phosphoserine(CK2)HMM predict
734Phosphoserine(MAPK)HMM predict
748Phosphoserine(CK2)HMM predict
760Phosphoserine(ATM)HMM predict
779Phosphothreonine(CDC2)HMM predict
795Phosphothreonine(CDC2)HMM predict
795Phosphothreonine(MAPK)HMM predict
809Phosphoserine(CK1)HMM predict
809Phosphoserine(IKK)HMM predict
870Phosphothreonine(PKA)HMM predict
870Phosphothreonine(PKC)HMM predict
891O-linkedHMM predict
899Phosphoserine(PKG)HMM predict
901N-linkedHMM predict
931Phosphoserine(CK1)HMM predict
938Phosphoserine(PKG)HMM predict
944Phosphoserine(CK1)HMM predict
951N-linkedHMM predict
974O-linkedHMM predict
1022N-linkedHMM predict
1032Phosphothreonine(PKC)HMM predict
1061N-linkedHMM predict
1067N-linkedHMM predict
1082Phosphoserine(CK2)HMM predict
1083Phosphoserine(CDC2)HMM predict
1095O-linkedHMM predict
1098Phosphoserine(CK2)HMM predict
1099Phosphoserine(CDC2)HMM predict
1105Phosphoserine(CK1)HMM predict
1105Phosphoserine(IKK)HMM predict
1131Phosphotyrosine(Jak)HMM predict
1148Phosphoserine(CK2)HMM predict
1149Phosphothreonine(CK2)HMM predict
1154O-linkedHMM predict
1159Phosphoserine(IKK)HMM predict
1163Phosphoserine(ATM)HMM predict
1166Phosphoserine(IKK)HMM predict
1169Phosphoserine(CK2)HMM predict
1170O-linkedHMM predict
1170Phosphoserine(CK1)HMM predict
1217Phosphoserine(CK1)HMM predict
1218Phosphoserine(CK1)HMM predict
1227Phosphoserine(CDC2)HMM predict
1227Phosphoserine(MAPK)HMM predict
1257Phosphoserine(PKG)HMM predict
1259Phosphoserine(CAMK2)HMM predict
1259PhosphoserineHMM predict
1280Phosphoserine(IKK)HMM predict
1307Phosphoserine(CK1)HMM predict
1307Phosphoserine(IKK)HMM predict
1353Phosphoserine(ATM)HMM predict
1367Phosphoserine(CK1)HMM predict
1384S-palmitoylHMM predict
1400Phosphothreonine(CDK)HMM predict
1416Phosphothreonine(PKA)HMM predict
1423MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033389
  • Location:chr17 24977090-25281143
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 25282557 25282864 307 1567
CTCF CD4SISSRdata 25282557 25282864 307 1567
CTCF G2GSE9613 25281028 25281461 433 101
CTCF G2GSE9613 25282493 25282762 269 1484
hScc1 BcellGSE12603 25281028 25281615 587 178
hScc1 BcellGSE12603 25282303 25282867 564 1442
hScc1 CdLSGSE12603 25282303 25282945 642 1481
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 24974553 24975255 702 2187
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 24990631 24991029 398 0
CTCF CD4GSE12889 25130433 25130669 236 0
CTCF CD4GSE12889 25158984 25159272 288 0
CTCF CD4GSE12889 25218934 25219276 342 0
CTCF CD4SISSRdata 24990631 24991029 398 0
CTCF CD4SISSRdata 25130433 25130669 236 0
CTCF CD4SISSRdata 25158984 25159272 288 0
CTCF CD4SISSRdata 25218934 25219276 342 0
CTCF HelaGSE12889 24990641 24990969 328 0
CTCF HelaGSE12889 25219014 25219204 190 0
CTCF JurkatGSE12889 24990667 24990940 273 0
CTCF G2GSE9613 24990636 24991002 366 0
CTCF G2GSE9613 25112324 25112689 365 0
CTCF G2GSE9613 25130438 25130658 220 0
ER E2-MCF7GSE14664 25125363 25125413 50 0
ER MCF7GSE19013 24990181 24990841 660 0
FOXA1 MCF7GSE15244 25095832 25096266 434 0
Fos K562GSE19551 25043224 25043838 614 0
Fos K562GSE19551 25061896 25062470 574 0
FoxA1 MCF7MACSdata 25095903 25096257 354 0
GABP HelaGSE8489 25077078 25077261 183 0
H3K4me3 colorectalcancer 25280138 25281112 974 0
H3ac HepG2E 25111688 25112057 369 0
H3ac HepG2E 25279833 25281028 1195 0
Jun K562GSE19551 25043376 25043716 340 0
Myc K562GSE19551 25061970 25062566 596 0
Myc K562GSE19551 25130479 25130800 321 0
Nanog ESGSE20650 25111931 25112537 606 0
Oct1 H2O2-HelaGSE14283 24990384 24990415 31 0
Oct1 H2O2-HelaGSE14283 24998496 24998524 28 0
Oct1 H2O2-HelaGSE14283 25135809 25135856 47 0
Oct1 H2O2-HelaGSE14283 25280495 25280527 32 0
Oct1 HelaGSE14283 24990381 24990416 35 0
Oct1 HelaGSE14283 24998491 24998532 41 0
Oct1 HelaGSE14283 25031329 25031358 29 0
Oct1 HelaGSE14283 25125364 25125436 72 0
Oct1 HelaGSE14283 25135809 25135856 47 0
Oct1 HelaGSE14283 25170824 25170852 28 0
Oct1 HelaGSE14283 25215213 25215245 32 0
Oct1 HelaGSE14283 25261895 25261931 36 0
Oct1 HelaGSE14283 25280497 25280528 31 0
P300 T30-glioblastomaGSE21026 25043089 25043944 855 0
PAX3-FKHR Rh4GSE19063 25221687 25223787 2100 0
PHF8 HeLaGSE20725 25280167 25282030 1863 0
RARA MCF7GSE15244 25061759 25062677 918 0
RARA MCF7GSE15244 25095979 25096266 287 0
RARG MCF7GSE15244 25061759 25062566 807 0
RARG MCF7GSE15244 25095979 25096266 287 0
RNAII Tamoxifen-MCF7GSE14664 25120808 25120905 97 0
Rb GrowingGSE19898 25112133 25112352 219 0
Rb GrowingGSE19898 25130611 25130784 173 0
Rb GrowingGSE19898 25206937 25207165 228 0
Rb QuiescentGSE19898 25111989 25112390 401 0
SRF k562GSE8489 25277725 25278014 289 0
STAT1 HeLaGSE12783 25060881 25063305 2424 0
TAF HelaGSE8489 25135820 25136138 318 0
TAF k562GSE8489 25244998 25245233 235 0
TAF k562GSE8489 25277725 25277978 253 0
TFAP2C MCF7GSE21234 25061938 25062508 570 0
TFAP2C MCF7GSE21234 25095793 25096432 639 0
hScc1 BcellGSE12603 24990533 24991192 659 0
hScc1 BcellGSE12603 25111616 25112532 916 0
hScc1 BcellGSE12603 25130339 25130658 319 0
hScc1 BcellGSE12603 25158767 25159243 476 0
hScc1 CdLSGSE12603 24990533 24991192 659 0
hScc1 CdLSGSE12603 25073437 25074130 693 0
hScc1 CdLSGSE12603 25130204 25130658 454 0
hScc1 CdLSGSE12603 25158588 25159243 655 0
hScc1 G2GSE9613 24990671 24991192 521 0
p130 SenescentGSE19898 25074873 25075112 239 0
p130 SenescentGSE19898 25112110 25112387 277 0
p63 keratinocytesGSE17611 24990294 24991130 836 0
p63 keratinocytesGSE17611 25142250 25142906 656 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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