Annotation Detail for GFM1

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Basic Information Top

Gene Symbol:	GFM1 ( COXPD1,EFG,EFG1,EFGM,EGF1,FLJ12662,FLJ13632,FLJ20773,GFM,hEFG1 )
Gene Full Name:	G elongation factor, mitochondrial 1
Band:	3q25.32
Quick Links	Entrez ID:85476; OMIM: 606639; Uniprot ID:EFGM_HUMAN; ENSEMBL ID: ENSG00000168827; HGNC ID: 13780
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
175	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	159844751	159845097	346	87
CTCF	CD4	SISSRdata	159844751	159845097	346	87
CTCF	G2	GSE9613	159827318	159827455	137	17624
CTCF	G2	GSE9613	159844717	159845241	524	32
P300	T30-glioblastoma	GSE21026	159844512	159845468	956	21

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	159860241	159860484	243
CTCF	CD4	SISSRdata	159860241	159860484	243
CTCF	G2	GSE9613	159860125	159860705	580
ETS1	Jurkat	GSE17954	159844601	159845562	961
Fos	K562	GSE19551	159879962	159880467	505
FoxA1	MCF7	MACSdata	159853029	159853273	244
Myc	K562	GSE19551	159844745	159845468	723
PHF8	293T	GSE20725	159844587	159845510	923
PHF8	HeLa	GSE20725	159844742	159845657	915
RARG	MCF7	GSE15244	159850417	159850696	279
Rb	Quiescent	GSE19898	159844879	159845176	297
Rb	Quiescent	GSE19898	159845186	159845324	138
Rb	Senescent	GSE19898	159844794	159845299	505
STAT1	HeLa	GSE12783	159885571	159886738	1167
TAFII	hES	GSE17917	159873005	159873429	424
hScc1	G2	GSE9613	159860198	159860705	507
p130	Quiescent	GSE19898	159844922	159845187	265
p130	Senescent	GSE19898	159844859	159845200	341
p130	shRbSenescent	GSE19898	159844881	159845377	496

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1043	Unknown	pSILAC	miR-16	GFM1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000168827		n_a	n_a	n_a	"epithelium, lymphoblast, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
18910	mRNA	GFM1	chr3	159845018	159893063	45	EST		chr3	159846603	159870085	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018