AutismKB 2.0

Annotation Detail for PRPF18


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Basic Information Top
Gene Symbol:PRPF18 ( FLJ10210,PRP18,hPrp18 )
Gene Full Name: PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae)
Band: 10p13
Quick LinksEntrez ID:8559; OMIM: 604993; Uniprot ID:PRP18_HUMAN; ENSEMBL ID: ENSG00000165630; HGNC ID: 17351
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
41Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
27Phosphotyrosine(Jak)HMM predict
103Phosphotyrosine(EGFR)HMM predict
103Phosphotyrosine(Syk)HMM predict
153Phosphothreonine(CK2)HMM predict
163N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003675
  • Location:chr10 13668944-13712872
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 13668735 13669116 381 19
CTCF CD4SISSRdata 13668735 13669116 381 19
ER Fulvestrant-MCF7GSE14664 13657744 13657827 83 11159
GABP k562GSE8489 13668304 13669303 999 141
Myc K562GSE19551 13668630 13669173 543 43
Oct1 H2O2-HelaGSE14283 13651392 13651423 31 17537
Oct1 H2O2-HelaGSE14283 13656529 13656559 30 12401
P300 T30-glioblastomaGSE21026 13668634 13669239 605 8
Rb QuiescentGSE19898 13668419 13668577 158 447
STAT1 IFNSISSRdata 13668593 13669206 613 45
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 13695657 13695776 119 0
CTCF CD4SISSRdata 13695657 13695776 119 0
ETS1 JurkatGSE17954 13668463 13669433 970 0
FoxA1 MCF7MACSdata 13696810 13697043 233 0
Oct1 H2O2-HelaGSE14283 13688620 13688651 31 0
Oct1 H2O2-HelaGSE14283 13690107 13690148 41 0
Oct1 HelaGSE14283 13688613 13688658 45 0
Oct1 HelaGSE14283 13690108 13690149 41 0
Oct4 hESGSE17917 13709794 13710095 301 0
Oct4 hESGSE21916 13709646 13710138 492 0
PHF8 Hs68plusFBSGSE20725 13668604 13669514 910 0
RARA MCF7GSE15244 13696742 13697310 568 0
RARG MCF7GSE15244 13696705 13697205 500 0
TFAP2C MCF7GSE21234 13696673 13697290 617 0
p130 SenescentGSE19898 13668833 13669075 242 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018