AutismKB 2.0

Annotation Detail for DENR


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Basic Information Top
Gene Symbol:DENR ( DRP,DRP1,SMAP-3 )
Gene Full Name: density-regulated protein
Band: 12q24.31
Quick LinksEntrez ID:8562; OMIM: 604550; Uniprot ID:DENR_HUMAN; ENSEMBL ID: ENSG00000139726; HGNC ID: 2769
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
69Phosphothreonine.
73Phosphoserine.
86Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
38O-linkedHMM predict
46Phosphotyrosine(Syk)HMM predict
46SulfotyrosineHMM predict
110Phosphothreonine(PKC)HMM predict
129Phosphothreonine(PKA)HMM predict
129Phosphothreonine(PKC)HMM predict
189Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003677
  • Location:chr12 121803323-121821904
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 121803029 121803342 313 138
CTCF CD4SISSRdata 121803029 121803342 313 138
CTCF HelaGSE12889 121802981 121803262 281 202
CTCF G2GSE9613 121802914 121803505 591 114
ETS1 JurkatGSE17954 121802841 121803787 946 10
Fos K562GSE19551 121800400 121800819 419 2714
Myc hESGSE17917 121803135 121803430 295 41
P300 T30-glioblastomaGSE21026 121802725 121803901 1176 11
RARG MCF7GSE15244 121800092 121800413 321 3071
hScc1 G2GSE9613 121802914 121803543 629 95
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 121803505 121805472 1967 0
PHF8 HeLaGSE20725 121802863 121803999 1136 0
PHF8 Hs68plusFBSGSE20725 121802582 121804180 1598 0
TAF HelaGSE8489 121803872 121805442 1570 0
TAF HelaGSE8489 121806980 121807528 548 0
hScc1 BcellGSE12603 121802914 121803801 887 0
hScc1 CdLSGSE12603 121802914 121804000 1086 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018