AutismKB 2.0

Annotation Detail for PRKRA


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Basic Information Top
Gene Symbol:PRKRA ( DYT16,PACT,RAX )
Gene Full Name: protein kinase, interferon-inducible double stranded RNA dependent activator
Band: 2q31.2
Quick LinksEntrez ID:8575; OMIM: 603424; Uniprot ID:PRKRA_HUMAN; ENSEMBL ID: ENSG00000180228; HGNC ID: 9438
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
18Phosphoserine.
246Phosphoserine.
287Phosphoserine.
Location(AA) Modifications Resource
18Phosphoserine.Swiss-Prot 53.0
18PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
118Phosphoserine(CDK)HMM predict
148Phosphoserine(ATM)HMM predict
160Phosphothreonine(PKA)HMM predict
194N-linkedHMM predict
199N-linkedHMM predict
221Phosphoserine(CDC2)HMM predict
221Phosphoserine(CDK)HMM predict
241Phosphotyrosine(Jak)HMM predict
241SulfotyrosineHMM predict
255N-linkedHMM predict
279Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003690
  • Location:chr2 179004395-179024109
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 179023499 179024829 1330 55
PHF8 293TGSE20725 179023194 179025037 1843 6
PHF8 Hs68minusFBSGSE20725 179023401 179024940 1539 61
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 178987724 178988017 293 16525
CTCF CD4SISSRdata 178987724 178988017 293 16525
CTCF G2GSE9613 178987655 178987943 288 16597
TAF k562GSE8489 178986908 178987835 927 17024
hScc1 BcellGSE12603 178987495 178987977 482 16660
hScc1 BcellGSE12603 178992112 178992479 367 12100
hScc1 CdLSGSE12603 178987456 178988301 845 16517
hScc1 CdLSGSE12603 178992000 178992408 408 12192
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 179021074 179023539 2465 0
PHF8 HeLaGSE20725 179023173 179025019 1846 0
hScc1 BcellGSE12603 179023582 179024168 586 0
hScc1 G2GSE9613 179023539 179024489 950 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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