AutismKB 2.0

Annotation Detail for TNFSF11


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Basic Information Top
Gene Symbol:TNFSF11 ( CD254,ODF,OPGL,OPTB2,RANKL,TRANCE,hRANKL2,sOdf )
Gene Full Name: tumor necrosis factor (ligand) superfamily, member 11
Band: 13q14
Quick LinksEntrez ID:8600; OMIM: 602642; Uniprot ID:TNF11_HUMAN; ENSEMBL ID: ENSG00000120659; HGNC ID: 11926
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
171N-linked (GlcNAc...) (Potential).
198N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
171N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
198N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
5Phosphoserine(PKC)HMM predict
158Phosphoserine(PKG)HMM predict
171N-linkedHMM predict
198N-linkedHMM predict
203N-linkedHMM predict
246O-linkedHMM predict
295N-linkedHMM predict
314ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003701
  • Location:chr13 42046297-42080147
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42085599 42085925 326 5615
Myc K562GSE19551 42087936 42088198 262 7920
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42046146 42046783 637 0
CTCF G2GSE9613 42047141 42047378 237 0
CTCF G2GSE9613 42067275 42067781 506 0
GABP HelaGSE8489 42070282 42070485 203 0
Myc hESGSE17917 42057836 42058141 305 0
Nanog hESGSE18292 42065612 42066160 548 0
Oct1 H2O2-HelaGSE14283 42060308 42060339 31 0
P300 T0-glioblastomaGSE21026 42066285 42067343 1058 0
RNAII Tamoxifen-MCF7GSE14664 42060218 42060256 38 0
hScc1 BcellGSE12603 42046338 42046750 412 0
hScc1 BcellGSE12603 42067092 42067717 625 0
hScc1 CdLSGSE12603 42046114 42046575 461 0
hScc1 CdLSGSE12603 42067129 42067646 517 0
hScc1 G2GSE9613 42046114 42046514 400 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-3p hsa-mir-125a 19 16331254
hsa-miR-125a-5p hsa-mir-125a 19 16331254
hsa-miR-155 hsa-mir-155 21 20039311
hsa-miR-155* hsa-mir-155 21 20039311
hsa-miR-195 hsa-mir-195 17 16331254
hsa-miR-195* hsa-mir-195 17 16331254
hsa-miR-200a hsa-mir-200a 1 16331254
hsa-miR-200a* hsa-mir-200a 1 16331254
hsa-miR-21 hsa-mir-21 17 21273303
hsa-miR-21 hsa-mir-21 17 20302778
hsa-miR-21* hsa-mir-21 17 21273303
hsa-miR-21* hsa-mir-21 17 20302778
hsa-miR-224 hsa-mir-224 X 16331254
hsa-miR-30b hsa-mir-30b 8 20302778
hsa-miR-30b* hsa-mir-30b 8 20302778
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7121 mRNA TNFSF11 chr13 42046297 42080148 145 EST chr13 42072860 42073126Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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