AutismKB 2.0

Annotation Detail for KLF7


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Basic Information Top
Gene Symbol:KLF7 ( UKLF )
Gene Full Name: Kruppel-like factor 7 (ubiquitous)
Band: 2q33.3
Quick LinksEntrez ID:8609; OMIM: 604865; Uniprot ID:KLF7_HUMAN; ENSEMBL ID: ENSG00000118263; HGNC ID: 6350
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
220Nuclear localization signal (Potential).
Location(AA) Modifications Resource
Location(AA) Modification Resource
42Phosphotyrosine(EGFR)HMM predict
45Phosphothreonine(PKC)HMM predict
51Phosphoserine(PKB)HMM predict
51Phosphoserine(PKG)HMM predict
117Phosphoserine(CK1)HMM predict
121O-linkedHMM predict
122Phosphotyrosine(Jak)HMM predict
135O-linkedHMM predict
137O-linkedHMM predict
137PhosphothreonineHMM predict
137Phosphothreonine(MAPK)HMM predict
137Phosphothreonine(CDK)HMM predict
189O-linkedHMM predict
199Phosphoserine(CK2)HMM predict
256S-palmitoylHMM predict
284S-farnesylHMM predict
284S-palmitoylHMM predict
287CysteineHMM predict
289Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003709
  • Location:chr2 207653773-207738858
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 207739085 207739471 386 420
Pol2 GM12878GSE19551 207738984 207740429 1445 848
Rb SenescentGSE19898 207739027 207739432 405 371
Rb shRbSenescenceGSE19898 207741054 207741334 280 2336
p130 QuiescentGSE19898 207739029 207739249 220 281
p130 QuiescentGSE19898 207739578 207739862 284 862
p130 SenescentGSE19898 207739615 207739904 289 901
p130 shRbQuiescentGSE19898 207739005 207739407 402 348
p130 shRbQuiescentGSE19898 207739651 207740172 521 1053
p130 shRbSenescentGSE19898 207738555 207739901 1346 370
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p63 keratinocytesGSE17611 207634028 207634850 822 19335
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 207738162 207738497 335 0
FOXA1 MCF7GSE15244 207736341 207737526 1185 0
H3K27me3 colorectalcancer 207736415 207739091 2676 0
H3K4me2 HCT116GSE10453 207736997 207737983 986 0
NRSF-poly JurkatQuESTdata 207733174 207733516 342 0
Nanog hESGSE18292 207696197 207696661 464 0
TAF k562GSE8489 207692978 207693201 223 0
hScc1 BcellGSE12603 207737808 207738581 773 0
p130 SenescentGSE19898 207737954 207738124 170 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018