AutismKB 2.0

Annotation Detail for PDE8B


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Basic Information Top
Gene Symbol:PDE8B ( ADSD,FLJ11212,PPNAD3 )
Gene Full Name: phosphodiesterase 8B
Band: 5q13.3
Quick LinksEntrez ID:8622; OMIM: 603390; Uniprot ID:PDE8B_HUMAN; ENSEMBL ID: ENSG00000113231; HGNC ID: 8794
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
517Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
23Phosphoserine(CK2)HMM predict
24Phosphoserine(CK1)HMM predict
25O-linkedHMM predict
25Phosphoserine(CDC2)HMM predict
29O-linkedHMM predict
30Phosphothreonine(PKA)HMM predict
31Phosphoserine(IKK)HMM predict
31O-linkedHMM predict
33Phosphoserine(ATM)HMM predict
56O-linkedHMM predict
59Phosphoserine(IKK)HMM predict
59O-linkedHMM predict
78O-linkedHMM predict
82O-linkedHMM predict
88O-linkedHMM predict
88Phosphothreonine(PKC)HMM predict
111Phosphoserine(CDK)HMM predict
143Phosphoserine(CK1)HMM predict
143Phosphoserine(ATM)HMM predict
187Phosphothreonine(PKA)HMM predict
203N-linkedHMM predict
241N-linkedHMM predict
351Phosphoserine(PKB)HMM predict
401Phosphoserine(ATM)HMM predict
401Phosphoserine(IKK)HMM predict
403Phosphothreonine(PKC)HMM predict
417Phosphoserine(PKG)HMM predict
428Phosphoserine(CK2)HMM predict
517Phosphoserine(PKA)HMM predict
517Phosphoserine(PKG)HMM predict
517Phosphoserine(PKC)HMM predict
521Phosphotyrosine(Jak)HMM predict
591N-linkedHMM predict
616N-linkedHMM predict
679N-linkedHMM predict
835Phosphoserine(CK2)HMM predict
870ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001029851
  • Location:chr5 76542461-76758981
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 76541291 76541587 296 1023
FOXA1 MCF7GSE15244 76536353 76537034 681 5768
GABP k562GSE8489 76541973 76542652 679 149
H3K27me3 colorectalcancer 76540686 76541618 932 1310
Oct1 H2O2-HelaGSE14283 76523711 76523739 28 18737
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 76690087 76690963 876 0
CTCF G2GSE9613 76542555 76542830 275 0
CTCF G2GSE9613 76551590 76551950 360 0
CTCF G2GSE9613 76636902 76637179 277 0
CTCF G2GSE9613 76679312 76679544 232 0
CTCF G2GSE9613 76694352 76694605 253 0
CTCF G2GSE9613 76696945 76697381 436 0
CTCF G2GSE9613 76730208 76730460 252 0
CTCF G2GSE9613 76749675 76749834 159 0
ER E2-MCF7GSE14664 76624470 76624504 34 0
ER E2-MCF7GSE14664 76647294 76647328 34 0
ER Fulvestrant-MCF7GSE14664 76621888 76621923 35 0
ER Fulvestrant-MCF7GSE14664 76624468 76624511 43 0
FOXA1 MCF7GSE15244 76599100 76599680 580 0
FOXA1 MCF7GSE15244 76642178 76642803 625 0
FOXA1 MCF7GSE15244 76757531 76758257 726 0
FoxA1 MCF7MACSdata 76633229 76633439 210 0
FoxA1 MCF7MACSdata 76757554 76757941 387 0
H3K27me3 colorectalcancer 76542860 76544854 1994 0
KLF4 hESGSE17917 76590639 76590795 156 0
NFkBII GM12878GSE19485 76687960 76689301 1341 0
Nanog ESGSE20650 76653432 76654307 875 0
Oct4 hESGSE17917 76577405 76577559 154 0
Oct4 hESGSE17917 76653697 76653928 231 0
P300 T0-glioblastomaGSE21026 76556223 76556665 442 0
P300 T30-glioblastomaGSE21026 76556026 76556927 901 0
P300 T30-glioblastomaGSE21026 76690110 76691020 910 0
RARA MCF7GSE15244 76572617 76573980 1363 0
RARA MCF7GSE15244 76599100 76599720 620 0
RARA MCF7GSE15244 76613422 76614613 1191 0
RARA MCF7GSE15244 76757312 76758632 1320 0
Rb GrowingGSE19898 76653508 76653777 269 0
Rb QuiescentGSE19898 76670995 76671202 207 0
TFAP2C MCF7GSE21234 76613598 76614668 1070 0
TFAP2C MCF7GSE21234 76757412 76758262 850 0
hScc1 BcellGSE12603 76547499 76547629 130 0
hScc1 BcellGSE12603 76730208 76730460 252 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21144 mRNA PDE8B chr5 76542461 76758982 383 EST chr5 76758232 76764870Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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