AutismKB 2.0

Annotation Detail for NCOA1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NCOA1 ( F-SRC-1,KAT13A,MGC129719,MGC129720,RIP160,SRC1,bHLHe42,bHLHe74 )
Gene Full Name: nuclear receptor coactivator 1
Band: 2p23.3
Quick LinksEntrez ID:8648; OMIM: 602691; Uniprot ID:NCOA1_HUMAN; ENSEMBL ID: ENSG00000084676; HGNC ID: 7668
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
22Phosphoserine.
50LXXLL motif 1.
103Phosphoserine.
116LXXLL motif 2.
372Phosphoserine.
395Phosphoserine.
517Phosphoserine.
569Phosphoserine.
637LXXLL motif 3.
694LXXLL motif 4.
753LXXLL motif 5.
917LXXLL motif 6.
1033Phosphoserine.
1179Phosphothreonine.
1185Phosphoserine.
1439LXXLL motif 7.
Location(AA) Modifications Resource
372Phosphoserine.Swiss-Prot 53.0
372PhosphoserinePhospho.ELM 6.0
395Phosphoserine.Swiss-Prot 53.0
395Phosphoserine (MAPK1)Phospho.ELM 6.0
517Phosphoserine.Swiss-Prot 53.0
517PhosphoserinePhospho.ELM 6.0
569Phosphoserine.Swiss-Prot 53.0
569PhosphoserinePhospho.ELM 6.0
732Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
774Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
1033Phosphoserine.Swiss-Prot 53.0
1033PhosphoserinePhospho.ELM 6.0
1179Phosphothreonine.Swiss-Prot 53.0
1179Phosphothreonine (MAPKAPK2)Phospho.ELM 6.0
1185Phosphoserine.Swiss-Prot 53.0
1185Phosphoserine (MAPKAPK2)Phospho.ELM 6.0
Location(AA) Modification Resource
9Phosphoserine(ATM)HMM predict
22Phosphoserine(IKK)HMM predict
26O-linkedHMM predict
53N-linkedHMM predict
88Phosphoserine(IKK)HMM predict
89Phosphothreonine(CK2)HMM predict
90Phosphothreonine(CK2)HMM predict
100Phosphoserine(CK1)HMM predict
101Phosphoserine(CK1)HMM predict
103Phosphoserine(ATM)HMM predict
139N-linkedHMM predict
153N-linkedHMM predict
231Phosphoserine(IKK)HMM predict
241Phosphoserine(IKK)HMM predict
245S-palmitoylHMM predict
308PhosphoserineHMM predict
322Phosphothreonine(PKA)HMM predict
325Phosphoserine(CDC2)HMM predict
369Phosphoserine(CK1)HMM predict
369Phosphoserine(IKK)HMM predict
372Phosphoserine(ATM)HMM predict
387N-linkedHMM predict
391N-linkedHMM predict
393O-linkedHMM predict
395O-linkedHMM predict
405Phosphothreonine(PKC)HMM predict
409Phosphoserine(IKK)HMM predict
428Phosphoserine(CK1)HMM predict
432Phosphoserine(IKK)HMM predict
433N-linkedHMM predict
434Phosphoserine(CK1)HMM predict
435Phosphoserine(CK1)HMM predict
436N-linkedHMM predict
437Phosphoserine(ATM)HMM predict
462Phosphoserine(ATM)HMM predict
465Phosphoserine(CK1)HMM predict
488Phosphoserine(CDC2)HMM predict
494Phosphothreonine(PKA)HMM predict
505N-linkedHMM predict
506N-linkedHMM predict
511N-linkedHMM predict
517Phosphoserine(CDC2)HMM predict
517Phosphoserine(CDK)HMM predict
517Phosphoserine(IKK)HMM predict
530N-linkedHMM predict
535N-linkedHMM predict
566Phosphoserine(ATM)HMM predict
569Phosphoserine(CDC2)HMM predict
598Phosphoserine(ATM)HMM predict
600N-linkedHMM predict
601Phosphoserine(CK1)HMM predict
602Phosphoserine(CK1)HMM predict
620Phosphoserine(CK1)HMM predict
624Phosphoserine(CK1)HMM predict
627Phosphoserine(CK1)HMM predict
627Phosphoserine(ATM)HMM predict
629Phosphothreonine(PKC)HMM predict
664O-linkedHMM predict
670N-linkedHMM predict
671Phosphoserine(CK1)HMM predict
675O-linkedHMM predict
675Phosphoserine(IKK)HMM predict
679O-linkedHMM predict
681Phosphoserine(CK1)HMM predict
684Phosphothreonine(PKC)HMM predict
718Phosphoserine(IKK)HMM predict
720Phosphoserine(IKK)HMM predict
763Phosphothreonine(CDK)HMM predict
787N-linkedHMM predict
789O-linkedHMM predict
789Phosphothreonine(MAPK)HMM predict
858O-linkedHMM predict
893N-linkedHMM predict
894N-linkedHMM predict
900N-linkedHMM predict
991Phosphotyrosine(INSR)HMM predict
991Phosphotyrosine(SRC)HMM predict
995Phosphotyrosine(Syk)HMM predict
997Phosphoserine(CDC2)HMM predict
997Phosphoserine(ATM)HMM predict
1026Phosphothreonine(CDC2)HMM predict
1026Phosphothreonine(MAPK)HMM predict
1026Phosphothreonine(CDK)HMM predict
1033O-linkedHMM predict
1043Phosphothreonine(PKC)HMM predict
1118Phosphoserine(ATM)HMM predict
1139Phosphoserine(PKA)HMM predict
1139Phosphoserine(IKK)HMM predict
1148O-linkedHMM predict
1179O-linkedHMM predict
1179Phosphothreonine(MAPK)HMM predict
1179Phosphothreonine(CDK)HMM predict
1183O-linkedHMM predict
1184O-linkedHMM predict
1184Phosphothreonine(PKC)HMM predict
1185Phosphoserine(IKK)HMM predict
1188Phosphoserine(ATM)HMM predict
1248O-linkedHMM predict
1250Phosphoserine(CDC2)HMM predict
1250Phosphoserine(MAPK)HMM predict
1250Phosphoserine(ATM)HMM predict
1253O-linkedHMM predict
1266O-linkedHMM predict
1271Phosphothreonine(MAPK)HMM predict
1271PhosphothreonineHMM predict
1277Phosphotyrosine(Syk)HMM predict
1312Phosphotyrosine(INSR)HMM predict
1417O-linkedHMM predict
1417Phosphothreonine(PKC)HMM predict
1421O-linkedHMM predict
1422O-linkedHMM predict
1422Phosphoserine(IKK)HMM predict
1426Phosphothreonine(CDC2)HMM predict
1426Phosphothreonine(MAPK)HMM predict
1427ProlineHMM predict
1433Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_147223
  • Location:chr2 24660849-24847071
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 24656594 24656621 27 4242
Oct1 HelaGSE14283 24655232 24655260 28 5604
RNAII Tamoxifen-MCF7GSE14664 24655963 24656053 90 4842
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF HelaGSE8489 24849029 24849202 173 2044
TAF HelaGSE8489 24851665 24851940 275 4731
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 24778889 24779832 943 0
CTCF G2GSE9613 24818329 24818627 298 0
ER E2-MCF7GSE14664 24767509 24767552 43 0
ER E2-MCF7GSE14664 24771986 24772068 82 0
ER E2-MCF7GSE14664 24802766 24802798 32 0
FoxA1 MCF7MACSdata 24774625 24774773 148 0
Myc K562GSE19551 24711581 24711837 256 0
NFkBII GM10847GSE19485 24662972 24664207 1235 0
NFkBII GM12878GSE19485 24662445 24664439 1994 0
NFkBII GM12892GSE19485 24662561 24664201 1640 0
NFkBII GM18526GSE19485 24662569 24664199 1630 0
Nanog hESGSE18292 24831386 24832009 623 0
Oct1 H2O2-HelaGSE14283 24731628 24731659 31 0
Oct1 H2O2-HelaGSE14283 24735661 24735691 30 0
Oct1 H2O2-HelaGSE14283 24754857 24754891 34 0
Oct1 H2O2-HelaGSE14283 24780452 24780479 27 0
Oct1 HelaGSE14283 24662639 24662689 50 0
Oct1 HelaGSE14283 24717273 24717358 85 0
Oct1 HelaGSE14283 24731628 24731659 31 0
Oct1 HelaGSE14283 24735660 24735690 30 0
Oct1 HelaGSE14283 24739946 24739988 42 0
Oct1 HelaGSE14283 24767515 24767551 36 0
P300 T30-glioblastomaGSE21026 24778876 24779594 718 0
TAF HelaGSE8489 24740554 24740749 195 0
TAF k562GSE8489 24683487 24683720 233 0
TFAP2C MCF7GSE21234 24689519 24690075 556 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
14025 mRNA NCOA1 chr2 24718996 24905219 131 EST chr2 24796489 24826221Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved