AutismKB 2.0

Annotation Detail for MAPKSP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAPKSP1 ( MAP2K1IP1,MAPBP,MP1 )
Gene Full Name: MAPK scaffold protein 1
Band: 4q23
Quick LinksEntrez ID:8649; OMIM: 603296; Uniprot ID:MPKS1_HUMAN; ENSEMBL ID: ENSG00000109270; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021970
  • Location:chr4 101021393-101034725
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 101025368 101025569 201 0
CTCF CD4SISSRdata 101025368 101025569 201 0
CTCF G2GSE9613 101034345 101034892 547 0
ETS1 JurkatGSE17954 101034101 101035100 999 0
H3K4me2 HCT116GSE10453 101033485 101034019 534 0
H3K4me3 colorectalcancer 101033485 101034142 657 0
H3ac HepG2E 101033485 101034537 1052 0
Nanog hESGSE18292 101025388 101025553 165 0
Oct1 HelaGSE14283 101028929 101028977 48 0
Oct1 HelaGSE14283 101029681 101029757 76 0
Oct4 hESGSE17917 101034449 101034889 440 0
PHF8 293TGSE20725 101034233 101035022 789 0
PHF8 Hs68minusFBSGSE20725 101034224 101034948 724 0
Sox2 hESGSE18292 101025382 101025538 156 0
USF1 HepG2E 101033485 101035058 1573 0
USF2 HepG2E 101033628 101034640 1012 0
hScc1 BcellGSE12603 101034431 101034857 426 0
hScc1 CdLSGSE12603 101025176 101025425 249 0
p130 shRbQuiescentGSE19898 101034207 101034548 341 0
Validated miRNA targets Top
No data
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1067 Unknown pSILAC miR-16 MAP2K1IP1 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000109270 n_a n_a n_a "epithelium, lymphocyte, leukocyte, macrophage, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018