AutismKB 2.0

Annotation Detail for EIF3A


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Basic Information Top
Gene Symbol:EIF3A ( EIF3,EIF3S10,KIAA0139,P167,TIF32,eIF3-p170,eIF3-theta,p180,p185 )
Gene Full Name: eukaryotic translation initiation factor 3, subunit A
Band: 10q26.11
Quick LinksEntrez ID:8661; OMIM: 602039; Uniprot ID:EIF3A_HUMAN; ENSEMBL ID: ENSG00000107581; HGNC ID: 3271
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
68N6-acetyllysine.
382Phosphotyrosine.
492Phosphoserine.
584Phosphoserine.
881Phosphoserine.
1198Phosphoserine.
1336Phosphoserine.
1364Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003750
  • Location:chr10 120784531-120830323
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Breast-CancerGSE22609 120830664 120831133 469 575
H3ac HepG2E 120830410 120831130 720 447
H3ac HepG2E 120833936 120834517 581 3903
RARA MCF7GSE15244 120830518 120831018 500 445
RARG MCF7GSE15244 120830559 120831130 571 521
TAF k562GSE8489 120830559 120831130 571 521
USF1 HepG2E 120830337 120831130 793 410
USF2 HepG2E 120830378 120831130 752 431
p130 SenescentGSE19898 120830018 120830809 791 90
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 120829011 120829510 499 0
H3K4me3 colorectalcancer 120828282 120829759 1477 0
H3ac HepG2E 120828089 120829759 1670 0
NFkBII GM12892GSE19485 120829145 120831219 2074 0
Oct1 H2O2-HelaGSE14283 120784980 120785020 40 0
Oct1 H2O2-HelaGSE14283 120793005 120793035 30 0
Oct1 H2O2-HelaGSE14283 120829635 120829680 45 0
Oct1 HelaGSE14283 120784970 120785016 46 0
Oct1 HelaGSE14283 120793004 120793037 33 0
Oct1 HelaGSE14283 120829634 120829679 45 0
Oct4 ESGSE20650 120816603 120816731 128 0
PHF8 293TGSE20725 120829370 120831105 1735 0
PHF8 HeLaGSE20725 120829437 120830851 1414 0
RARA MCF7GSE15244 120829011 120829612 601 0
TAF HelaGSE8489 120827980 120829510 1530 0
TAF k562GSE8489 120827980 120829541 1561 0
USF1 HepG2E 120828184 120829759 1575 0
hScc1 BcellGSE12603 120829794 120830738 944 0
hScc1 CdLSGSE12603 120829541 120830841 1300 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 18818519
hsa-let-7a hsa-let-7a-2 11 18818519
hsa-let-7a hsa-let-7a-3 22 18818519
hsa-let-7a* hsa-let-7a-1 9 18818519
hsa-let-7a* hsa-let-7a-3 22 18818519
hsa-let-7b hsa-let-7b 22 18818519
hsa-let-7b* hsa-let-7b 22 18818519
hsa-let-7c hsa-let-7c 21 18818519
hsa-let-7c* hsa-let-7c 21 18818519
hsa-let-7d hsa-let-7d 9 18818519
hsa-let-7d* hsa-let-7d 9 18818519
hsa-let-7e hsa-let-7e 19 18818519
hsa-let-7e* hsa-let-7e 19 18818519
hsa-let-7f hsa-let-7f-1 9 18818519
hsa-let-7f hsa-let-7f-2 X 18818519
hsa-let-7f-1* hsa-let-7f-1 9 18818519
hsa-let-7f-2* hsa-let-7f-2 X 18818519
hsa-let-7g hsa-let-7g 3 18818519
hsa-let-7g* hsa-let-7g 3 18818519
hsa-let-7i hsa-let-7i 12 18818519
hsa-let-7i* hsa-let-7i 12 18818519
hsa-miR-101 hsa-mir-101-1 1 20412057
hsa-miR-101 hsa-mir-101-2 9 20412057
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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