Annotation Detail for CDC23
Basic Information Top
| Gene Symbol: | CDC23 ( ANAPC8,APC8 ) |
|---|---|
| Gene Full Name: | cell division cycle 23 homolog (S. cerevisiae) |
| Band: | 5q31.2 |
| Quick Links | Entrez ID:8697; OMIM: 603462; Uniprot ID:CDC23_HUMAN; ENSEMBL ID: ENSG00000094880; HGNC ID: 1724 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 273 | Phosphotyrosine. | |
| 467 | N6-acetyllysine. | |
| 562 | Phosphothreonine. | |
| 565 | Phosphothreonine. | |
| 576 | Phosphoserine. | |
| 578 | Phosphoserine. | |
| 582 | Phosphothreonine. | |
| 584 | Phosphothreonine. | |
| 588 | Phosphoserine. | |
| 593 | Phosphoserine. | |
| 596 | Phosphothreonine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 267 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 267 | Phosphotyrosine | Phospho.ELM 6.0 |
| 556 | Phosphothreonine. | Swiss-Prot 53.0 |
| 556 | Phosphothreonine (CDK1;PLK1) | Phospho.ELM 6.0 |
| 559 | Phosphothreonine. | Swiss-Prot 53.0 |
| 559 | Phosphothreonine (CDK1;PLK1) | Phospho.ELM 6.0 |
| 572 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 576 | Phosphothreonine (CDK1) | Phospho.ELM 6.0 |
| 582 | Phosphoserine | Phospho.ELM 6.0 |
| 582 | Phosphoserine. | Swiss-Prot 53.0 |
| 587 | Phosphoserine | Phospho.ELM 6.0 |
| 590 | Phosphothreonine. | Swiss-Prot 53.0 |
| 590 | Phosphothreonine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 7 | O-linked | HMM predict |
| 323 | Phosphotyrosine(Jak) | HMM predict |
| 369 | Phosphotyrosine(INSR) | HMM predict |
| 475 | Phosphothreonine(CK2) | HMM predict |
| 534 | N-linked | HMM predict |
| 556 | Phosphothreonine(MAPK) | HMM predict |
| 574 | N-linked | HMM predict |
| 575 | N-linked | HMM predict |
| 576 | Phosphothreonine(CDC2) | HMM predict |
| 576 | Phosphothreonine(MAPK) | HMM predict |
| 582 | Phosphoserine(PKG) | HMM predict |
| 582 | Phosphoserine(CAMK2) | HMM predict |
| 585 | N-linked | HMM predict |
- RefSeq ID: NM_004661
- Location:chr5 137551239-137576917
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 137586345 | 137586679 | 334 | 9595 |
| E2F4 | G0 | GSE7516 | 137576631 | 137577459 | 828 | 128 |
| ETS1 | Jurkat | GSE17954 | 137576438 | 137577540 | 1102 | 72 |
| FOXA1 | MCF7 | GSE15244 | 137576599 | 137577459 | 860 | 112 |
| Fos | K562 | GSE19551 | 137576680 | 137577408 | 728 | 127 |
| LIN54 | G0 | GSE7516 | 137576712 | 137577273 | 561 | 75 |
| NFkBII | GM12878 | GSE19485 | 137576333 | 137577590 | 1257 | 44 |
| P300 | T30-glioblastoma | GSE21026 | 137576468 | 137577501 | 1033 | 67 |
| PHF8 | 293T | GSE20725 | 137577264 | 137577810 | 546 | 620 |
| Rb | Growing | GSE19898 | 137577016 | 137577277 | 261 | 229 |
| Rb | Quiescent | GSE19898 | 137576782 | 137577384 | 602 | 166 |
| Rb | Senescent | GSE19898 | 137576673 | 137577366 | 693 | 102 |
| STAT1 | IFN | SISSRdata | 137586290 | 137586803 | 513 | 9629 |
| TAFII | hES | GSE17917 | 137576696 | 137577219 | 523 | 40 |
| hScc1 | Bcell | GSE12603 | 137586345 | 137586679 | 334 | 9595 |
| hScc1 | Bcell | GSE12603 | 137593810 | 137594026 | 216 | 17001 |
| hScc1 | CdLS | GSE12603 | 137586345 | 137586789 | 444 | 9650 |
| p130 | Quiescent | GSE19898 | 137576884 | 137577452 | 568 | 251 |
| p130 | Senescent | GSE19898 | 137576610 | 137577573 | 963 | 174 |
| p130 | shRbQuiescent | GSE19898 | 137576537 | 137577586 | 1049 | 144 |
| p130 | shRbSenescent | GSE19898 | 137576430 | 137577491 | 1061 | 43 |
| p130 | S | GSE7516 | 137576712 | 137577459 | 747 | 168 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3K4me3 | colorectal | cancer | 137576210 | 137577186 | 976 | 0 |
| H3ac | HepG2 | E | 137576210 | 137576879 | 669 | 0 |
| LIN9 | G0 | GSE7516 | 137576364 | 137577459 | 1095 | 0 |
| LIN9 | S | GSE7516 | 137576210 | 137577459 | 1249 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 137553202 | 137553230 | 28 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 137561470 | 137561496 | 26 | 0 |
| Oct1 | Hela | GSE14283 | 137553198 | 137553232 | 34 | 0 |
| Oct1 | Hela | GSE14283 | 137561465 | 137561499 | 34 | 0 |
| P300 | T0-glioblastoma | GSE21026 | 137576336 | 137577425 | 1089 | 0 |
| PHF8 | 293T | GSE20725 | 137576552 | 137577193 | 641 | 0 |
| PolII | HeLa | GSE12783 | 137576280 | 137577506 | 1226 | 0 |
| Stat6 | IL-4-hr1 | GSE17850 | 137555819 | 137556380 | 561 | 0 |
| TAF | Hela | GSE8489 | 137561926 | 137562388 | 462 | 0 |
| TAF | Hela | GSE8489 | 137576210 | 137576953 | 743 | 0 |
| p130 | G0 | GSE7516 | 137576318 | 137577459 | 1141 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21514 | mRNA | KIF20A | chr5 | 137543247 | 137551259 | 24 | mRNA | CDC23 | chr5 | 137551235 | 137576918 | Sense/Antisense (SA) pairs |