Annotation Detail for CBS
Basic Information Top
| Gene Symbol: | CBS ( HIP4 ) |
|---|---|
| Gene Full Name: | cystathionine-beta-synthase |
| Band: | 21q22.3 |
| Quick Links | Entrez ID:875; OMIM: 613381; Uniprot ID:CBS_HUMAN; ENSEMBL ID: ENSG00000160200; HGNC ID: 1550 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 19 | Phosphoserine. | |
| 119 | N6-(pyridoxal phosphate)lysine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 211 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 5 | Phosphothreonine(MAPK) | HMM predict |
| 23 | Phosphoserine(IKK) | HMM predict |
| 61 | O-linked | HMM predict |
| 294 | N-linked | HMM predict |
| 301 | Phosphotyrosine(SRC) | HMM predict |
| 301 | Phosphotyrosine(INSR) | HMM predict |
| 301 | Phosphotyrosine(Syk) | HMM predict |
| 352 | O-linked | HMM predict |
| 428 | O-linked | HMM predict |
| 524 | Phosphoserine(CDC2) | HMM predict |
| 525 | Phosphoserine(ATM) | HMM predict |
- RefSeq ID: NM_000071
- Location:chr21 43346371-43369492
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| hScc1 | Bcell | GSE12603 | 43369387 | 43369841 | 454 | 122 |
| p130 | Senescent | GSE19898 | 43373080 | 43373553 | 473 | 3824 |
| p130 | shRbSenescent | GSE19898 | 43373258 | 43373597 | 339 | 3935 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Myc | K562 | GSE19551 | 43342634 | 43343459 | 825 | 3325 |
| RARA | MCF7 | GSE15244 | 43338648 | 43339498 | 850 | 7299 |
| TFAP2C | MCF7 | GSE21234 | 43338460 | 43339876 | 1416 | 7204 |
| p130 | shRbQuiescent | GSE19898 | 43338296 | 43338858 | 562 | 7795 |
| p130 | shRbSenescent | GSE19898 | 43338718 | 43338864 | 146 | 7581 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 43347027 | 43347250 | 223 | 0 |
| Rb | Quiescent | GSE19898 | 43368319 | 43368673 | 354 | 0 |
| Rb | Senescent | GSE19898 | 43368760 | 43368966 | 206 | 0 |
| TFAP2C | MCF7 | GSE21234 | 43368205 | 43368671 | 466 | 0 |
| hScc1 | Bcell | GSE12603 | 43349502 | 43350043 | 541 | 0 |
| hScc1 | Bcell | GSE12603 | 43356860 | 43357283 | 423 | 0 |
| hScc1 | Bcell | GSE12603 | 43359216 | 43359625 | 409 | 0 |
| hScc1 | Bcell | GSE12603 | 43361493 | 43361867 | 374 | 0 |
| hScc1 | Bcell | GSE12603 | 43367670 | 43368200 | 530 | 0 |
| p130 | Senescent | GSE19898 | 43368203 | 43368715 | 512 | 0 |
| p130 | shRbSenescent | GSE19898 | 43368544 | 43368697 | 153 | 0 |
| p130 | shRbSenescent | GSE19898 | 43368769 | 43369019 | 250 | 0 |
| p63 | keratinocytes | GSE17611 | 43345943 | 43346823 | 880 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7a | hsa-let-7a-1 | 9 | 19431195 |
| hsa-let-7a | hsa-let-7a-2 | 11 | 19431195 |
| hsa-let-7a | hsa-let-7a-3 | 22 | 19431195 |
| hsa-let-7a* | hsa-let-7a-1 | 9 | 19431195 |
| hsa-let-7a* | hsa-let-7a-3 | 22 | 19431195 |
| hsa-let-7b | hsa-let-7b | 22 | 19431195 |
| hsa-let-7b* | hsa-let-7b | 22 | 19431195 |
| hsa-let-7c | hsa-let-7c | 21 | 19431195 |
| hsa-let-7c* | hsa-let-7c | 21 | 19431195 |
| hsa-let-7d | hsa-let-7d | 9 | 19431195 |
| hsa-let-7d* | hsa-let-7d | 9 | 19431195 |
| hsa-let-7e | hsa-let-7e | 19 | 19431195 |
| hsa-let-7e* | hsa-let-7e | 19 | 19431195 |
| hsa-let-7f | hsa-let-7f-1 | 9 | 19431195 |
| hsa-let-7f | hsa-let-7f-2 | X | 19431195 |
| hsa-let-7f-1* | hsa-let-7f-1 | 9 | 19431195 |
| hsa-let-7f-2* | hsa-let-7f-2 | X | 19431195 |
| hsa-let-7g | hsa-let-7g | 3 | 19431195 |
| hsa-let-7g* | hsa-let-7g | 3 | 19431195 |
| hsa-let-7i | hsa-let-7i | 12 | 19431195 |
| hsa-let-7i* | hsa-let-7i | 12 | 19431195 |
| No data |
Cis-Nats regulation