AutismKB 2.0

Annotation Detail for NAPG


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Basic Information Top
Gene Symbol:NAPG ( GAMMASNAP )
Gene Full Name: N-ethylmaleimide-sensitive factor attachment protein, gamma
Band: 18p11.22
Quick LinksEntrez ID:8774; OMIM: 603216; Uniprot ID:SNAG_HUMAN; ENSEMBL ID: ENSG00000134265; HGNC ID: 7642
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
284Phosphoserine (By similarity).
307Phosphotyrosine.
Location(AA) Modifications Resource
284Phosphoserine (By similarity).Swiss-Prot 53.0
307Phosphotyrosine.Swiss-Prot 53.0
307PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
108N-linkedHMM predict
176Phosphoserine(PKG)HMM predict
184Phosphotyrosine(Syk)HMM predict
184Phosphotyrosine(SRC)HMM predict
184Phosphotyrosine(INSR)HMM predict
184Phosphotyrosine(EGFR)HMM predict
210Phosphotyrosine(EGFR)HMM predict
256Phosphoserine(CDC2)HMM predict
266Phosphotyrosine(Syk)HMM predict
284Phosphoserine(CDC2)HMM predict
287Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003826
  • Location:chr18 10516030-10540370
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 10510200 10510394 194 5734
CTCF CD4SISSRdata 10510200 10510394 194 5734
CTCF G2GSE9613 10509968 10510417 449 5838
CTCF G2GSE9613 10515883 10516022 139 78
P300 T30-glioblastomaGSE21026 10515729 10516329 600 2
RNAII Tamoxifen-MCF7GSE14664 10508455 10508529 74 7539
hScc1 BcellGSE12603 10509933 10510892 959 5618
hScc1 CdLSGSE12603 10509933 10510591 658 5769
hScc1 G2GSE9613 10509898 10510858 960 5653
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 10550499 10550835 336 10297
CTCF CD4SISSRdata 10550499 10550835 336 10297
CTCF G2GSE9613 10549909 10551007 1098 10088
hScc1 BcellGSE12603 10548665 10548941 276 8433
hScc1 BcellGSE12603 10550270 10551007 737 10268
hScc1 CdLSGSE12603 10550234 10550932 698 10213
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 10526142 10526183 41 0
ETS1 JurkatGSE17954 10515602 10516836 1234 0
H3K4me3 colorectalcancer 10517403 10517860 457 0
H3ac HepG2E 10516664 10516877 213 0
H3ac HepG2E 10517403 10517860 457 0
H3ac HepG2E 10518224 10519097 873 0
Oct1 H2O2-HelaGSE14283 10525171 10525200 29 0
Oct1 HelaGSE14283 10525116 10525205 89 0
Oct1 HelaGSE14283 10526140 10526184 44 0
hScc1 BcellGSE12603 10515809 10516337 528 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1071 Unknown pSILAC miR-16 NAPG down 50-25% 18668040
1251 Unknown pSILAC miR-30 NAPG down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000134265 n_a n_a n_a "lymphocyte, muscle cell" "malignant tumour, carcinoma, leukaemia"
ENSG00000134265 n_a n_a n_a "lymphocyte, muscle cell" "malignant tumour, carcinoma, leukaemia"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018