AutismKB 2.0

Annotation Detail for MPDZ


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MPDZ ( DKFZp781P216,FLJ25909,FLJ34626,FLJ90240,MUPP1 )
Gene Full Name: multiple PDZ domain protein
Band: 9p23
Quick LinksEntrez ID:8777; OMIM: 603785; Uniprot ID:MPDZ_HUMAN; ENSEMBL ID: ENSG00000107186; HGNC ID: 7208
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
230Phosphoserine.
353Phosphoserine.
354Phosphoserine.
358Phosphothreonine.
483Phosphoserine.
Location(AA) Modifications Resource
483Phosphoserine.Swiss-Prot 53.0
483PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
19Phosphothreonine(PKC)HMM predict
42Phosphoserine(CDC2)HMM predict
70Phosphoserine(CK2)HMM predict
236Phosphoserine(CDK)HMM predict
238Phosphoserine(IKK)HMM predict
238PhosphoserineHMM predict
238Phosphoserine(PKB)HMM predict
238O-linkedHMM predict
350O-linkedHMM predict
352O-linkedHMM predict
353O-linkedHMM predict
354Phosphoserine(ATM)HMM predict
354Phosphoserine(CDK)HMM predict
354Phosphoserine(IKK)HMM predict
354Phosphoserine(CDC2)HMM predict
356O-linkedHMM predict
357Phosphoserine(IKK)HMM predict
358Phosphothreonine(CDK)HMM predict
458Phosphothreonine(PKC)HMM predict
502Phosphoserine(CK1)HMM predict
507Phosphothreonine(PKA)HMM predict
517Phosphotyrosine(INSR)HMM predict
641Phosphoserine(IKK)HMM predict
667Phosphoserine(CK2)HMM predict
717SulfotyrosineHMM predict
763Phosphoserine(CK1)HMM predict
778Phosphothreonine(PKC)HMM predict
790Phosphoserine(CDC2)HMM predict
790Phosphoserine(MAPK)HMM predict
795Phosphotyrosine(SRC)HMM predict
797Phosphoserine(CK2)HMM predict
839Phosphoserine(CK2)HMM predict
843Phosphoserine(CDC2)HMM predict
846Phosphoserine(IKK)HMM predict
849N-linkedHMM predict
861Phosphoserine(CK1)HMM predict
876O-linkedHMM predict
880Phosphoserine(ATM)HMM predict
880Phosphoserine(CDC2)HMM predict
959O-linkedHMM predict
981Phosphotyrosine(INSR)HMM predict
999N-linkedHMM predict
1078Phosphoserine(CAMK2)HMM predict
1078Phosphoserine(PKG)HMM predict
1078PhosphoserineHMM predict
1199N-linkedHMM predict
1249Phosphoserine(CDC2)HMM predict
1249Phosphoserine(CDK)HMM predict
1263N-linkedHMM predict
1268N-linkedHMM predict
1283Phosphoserine(ATM)HMM predict
1283Phosphoserine(CK1)HMM predict
1287Phosphoserine(CK2)HMM predict
1287Phosphoserine(ATM)HMM predict
1296Phosphoserine(ATM)HMM predict
1296O-linkedHMM predict
1318Phosphoserine(CK1)HMM predict
1321Phosphoserine(ATM)HMM predict
1467O-linkedHMM predict
1567Phosphoserine(ATM)HMM predict
1583N-linkedHMM predict
1595Phosphoserine(CDC2)HMM predict
1603N-linkedHMM predict
1604Phosphothreonine(PKC)HMM predict
1700Phosphothreonine(MAPK)HMM predict
1700Phosphothreonine(CDC2)HMM predict
1715Phosphotyrosine(Syk)HMM predict
1745N-linkedHMM predict
1747Phosphothreonine(PKA)HMM predict
1782N-linkedHMM predict
1813O-linkedHMM predict
1813Phosphoserine(CK2)HMM predict
1815O-linkedHMM predict
1815Phosphoserine(IKK)HMM predict
1820Phosphoserine(CK1)HMM predict
1907N-linkedHMM predict
1938Phosphoserine(IKK)HMM predict
1959Phosphoserine(IKK)HMM predict
1987Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003829
  • Location:chr9 13096577-13240356
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 13257642 13258128 486 17529
Rb GrowingGSE19898 13257860 13258086 226 17617
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 13078866 13079091 225 17599
CTCF CD4SISSRdata 13078866 13079091 225 17599
TFAP2C MCF7GSE21234 13084207 13084648 441 12150
hScc1 BcellGSE12603 13078739 13079246 507 17585
hScc1 CdLSGSE12603 13078631 13079327 696 17599
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 13130860 13131045 185 0
Nanog ESGSE20650 13108292 13108684 392 0
Oct1 H2O2-HelaGSE14283 13100379 13100411 32 0
Oct1 HelaGSE14283 13166232 13166265 33 0
Oct1 HelaGSE14283 13179418 13179454 36 0
Oct1 HelaGSE14283 13211939 13212014 75 0
TFAP2C MCF7GSE21234 13171605 13172028 423 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26214 EST chr9 13176415 13180653 138 mRNA MPDZ chr9 13096575 13240357Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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