AutismKB 2.0

Annotation Detail for TNFRSF10B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TNFRSF10B ( CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10b
Band: 8p21.3
Quick LinksEntrez ID:8795; OMIM: 603612; Uniprot ID:TR10B_HUMAN; ENSEMBL ID: ENSG00000120889; HGNC ID: 11905
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
15MethylarginineHMM predict
26MethylarginineHMM predict
75Phosphoserine(CDC2)HMM predict
77O-linkedHMM predict
127Phosphoserine(IKK)HMM predict
197O-linkedHMM predict
197O-linkedHMM predict
199O-linkedHMM predict
199O-linkedHMM predict
200O-linkedHMM predict
200O-linkedHMM predict
201O-linkedHMM predict
201Phosphoserine(CDC2)HMM predict
204Phosphothreonine(CDC2)HMM predict
204O-linkedHMM predict
204Phosphothreonine(CDK)HMM predict
207Phosphoserine(IKK)HMM predict
381Phosphothreonine(PKA)HMM predict
391N-linkedHMM predict
398Phosphoserine(CAMK2)HMM predict
408Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003842
  • Location:chr8 22933592-22982636
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 22987739 22988940 1201 5703
CTCF CD4GSE12889 22997621 22997954 333 15151
CTCF CD4SISSRdata 22997621 22997954 333 15151
CTCF HelaGSE12889 22997714 22997879 165 15160
CTCF JurkatGSE12889 22997686 22997887 201 15150
CTCF G2GSE9613 22982671 22982873 202 136
CTCF G2GSE9613 22997360 22998523 1163 15305
FOXA1 DLD1GSE12801 22996653 22997064 411 14222
FOXA1 MCF7GSE15244 22987803 22988135 332 5333
Fos K562GSE19551 22987765 22988580 815 5536
H3ac HepG2E 22982435 22982873 438 18
NFkBII GM10847GSE19485 22987582 22988902 1320 5606
NFkBII GM12878GSE19485 22987392 22988729 1337 5424
NFkBII GM12892GSE19485 22987444 22988901 1457 5536
NFkBII GM15510GSE19485 22987445 22988950 1505 5561
NFkBII GM18505GSE19485 22987456 22988585 1129 5384
NFkBII GM18526GSE19485 22987485 22988837 1352 5525
P300 T30-glioblastomaGSE21026 22987540 22989208 1668 5738
RARG MCF7GSE15244 22987803 22988135 332 5333
TFAP2C MCF7GSE21234 22982292 22983028 736 24
p130 SenescentGSE19898 22982523 22982913 390 82
p130 SenescentGSE19898 22997492 22998191 699 15205
p130 shRbQuiescentGSE19898 22982302 22982998 696 14
p130 shRbQuiescentGSE19898 22987797 22988611 814 5568
p130 shRbSenescentGSE19898 22997723 22998134 411 15292
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22934189 22934395 206 0
CTCF G2GSE9613 22940409 22941069 660 0
CTCF G2GSE9613 22978452 22978877 425 0
CTCF G2GSE9613 22982009 22982399 390 0
ETS1 JurkatGSE17954 22982011 22983097 1086 0
H3ac HepG2E 22976900 22977150 250 0
H3ac HepG2E 22978414 22979106 692 0
H3ac HepG2E 22981028 22982165 1137 0
NRSF pAbJurkat 22934189 22934431 242 0
Nanog ESGSE20650 22963283 22963719 436 0
PHF8 293TGSE20725 22981908 22982807 899 0
Rb GrowingGSE19898 22977985 22978180 195 0
Rb GrowingGSE19898 22981308 22981463 155 0
Rb GrowingGSE19898 22982451 22982635 184 0
Rb SenescentGSE19898 22981751 22982113 362 0
Rb SenescentGSE19898 22982435 22982660 225 0
hScc1 BcellGSE12603 22981896 22982471 575 0
hScc1 CdLSGSE12603 22981382 22982471 1089 0
p130 QuiescentGSE19898 22981531 22982067 536 0
p130 QuiescentGSE19898 22982474 22982732 258 0
p130 SenescentGSE19898 22977986 22978479 493 0
p130 SenescentGSE19898 22981694 22981976 282 0
p130 SenescentGSE19898 22982108 22982482 374 0
p130 shRbSenescentGSE19898 22981646 22981816 170 0
p130 shRbSenescentGSE19898 22981953 22982737 784 0
p63 keratinocytesGSE17611 22955189 22956193 1004 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1299 Unknown pSILAC miR-30 TNFRSF10B down 75-50% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000120889 n_a n_a n_a "epithelium, squamous cell, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25168 mRNA RHOBTB2 chr8 22913406 22933653 58 mRNA TNFRSF10B chr8 22933595 22982637Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved