AutismKB 2.0

Annotation Detail for TNFRSF10A


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Basic Information Top
Gene Symbol:TNFRSF10A ( APO2,CD261,DR4,MGC9365,TRAILR-1,TRAILR1 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10a
Band: 8p21.3
Quick LinksEntrez ID:8797; OMIM: 603611; Uniprot ID:TR10A_HUMAN; ENSEMBL ID: ENSG00000104689; HGNC ID: 11904
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
83Phosphoserine.
156N-linked (GlcNAc...) (Potential).
463Phosphoserine.
466Phosphoserine.
Location(AA) Modifications Resource
83Phosphoserine.Swiss-Prot 53.0
83PhosphoserinePhospho.ELM 6.0
156N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
461PhosphothreoninePhospho.ELM 6.0
463Phosphoserine.Swiss-Prot 53.0
463PhosphoserinePhospho.ELM 6.0
466Phosphoserine.Swiss-Prot 53.0
466PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
33Phosphothreonine(MAPK)HMM predict
48MethylarginineHMM predict
52MethylarginineHMM predict
67MethylarginineHMM predict
154Phosphotyrosine(INSR)HMM predict
172PhosphoserineHMM predict
172Phosphoserine(CK2)HMM predict
178Phosphoserine(IKK)HMM predict
222Phosphothreonine(CDC2)HMM predict
261S-palmitoylHMM predict
263S-palmitoylHMM predict
317Phosphoserine(ATM)HMM predict
417N-linkedHMM predict
422N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003844
  • Location:chr8 23104915-23138583
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 23093481 23093520 39 11415
RNAII Tamoxifen-MCF7GSE14664 23093480 23093526 46 11413
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 23112085 23112308 223 0
CTCF CD4GSE12889 23138316 23138667 351 0
CTCF CD4SISSRdata 23112085 23112308 223 0
CTCF CD4SISSRdata 23138316 23138667 351 0
CTCF G2GSE9613 23112958 23113208 250 0
CTCF G2GSE9613 23115567 23115812 245 0
CTCF G2GSE9613 23132715 23133104 389 0
CTCF G2GSE9613 23137827 23138675 848 0
H3K4me3 colorectalcancer 23136873 23137273 400 0
H3ac HepG2E 23136905 23137477 572 0
P300 T30-glioblastomaGSE21026 23131139 23132824 1685 0
PHF8 HeLaGSE20725 23137156 23139273 2117 0
TFAP2C MCF7GSE21234 23137168 23137427 259 0
hScc1 BcellGSE12603 23137862 23138911 1049 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1012 Unknown pSILAC miR-155 TNFRSF10A down 75-50% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000104689 n_a n_a n_a lymphocyte "malignant tumour, carcinoma, leukaemia, non-Hodgkin's"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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