AutismKB 2.0

Annotation Detail for SUCLA2


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Basic Information Top
Gene Symbol:SUCLA2 ( A-BETA,SCS-betaA )
Gene Full Name: succinate-CoA ligase, ADP-forming, beta subunit
Band: 13q14.2
Quick LinksEntrez ID:8803; OMIM: 603921; Uniprot ID:SUCB1_HUMAN; ENSEMBL ID: ENSG00000136143; HGNC ID: 11448
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
78N6-acetyllysine.
84Phosphotyrosine.
143N6-acetyllysine.
279Phosphoserine (By similarity).
Location(AA) Modifications Resource
84Phosphotyrosine.Swiss-Prot 53.0
84PhosphotyrosinePhospho.ELM 6.0
279Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
54Phosphoserine(PKG)HMM predict
54Phosphoserine(CK1)HMM predict
58Phosphotyrosine(INSR)HMM predict
58Phosphotyrosine(SRC)HMM predict
58Phosphotyrosine(Syk)HMM predict
60Phosphoserine(INSR)HMM predict
79Phosphoserine(CDC2)HMM predict
124Phosphoserine(CDC2)HMM predict
462ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003850
  • Location:chr13 47414792-47473462
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 47473239 47473983 744 149
Nanog hESGSE18292 47483980 47484346 366 10701
Oct1 H2O2-HelaGSE14283 47477342 47477382 40 3900
Oct1 HelaGSE14283 47477342 47477381 39 3899
P300 T30-glioblastomaGSE21026 47481315 47482122 807 8256
Rb SenescentGSE19898 47473265 47473713 448 27
STAT1 IFNSISSRdata 47481342 47481923 581 8170
TFAP2C MCF7GSE21234 47481456 47481984 528 8258
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 47403624 47403659 35 11151
Nanog hESGSE18292 47405411 47406059 648 9058
Oct1 HelaGSE14283 47403590 47403655 65 11170
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 47473020 47473648 628 0
GABP HelaGSE8489 47464350 47464712 362 0
H3K4me3 colorectalcancer 47471982 47472429 447 0
H3ac HepG2E 47472182 47472899 717 0
Oct1 HelaGSE14283 47417846 47417877 31 0
PHF8 HeLaGSE20725 47472824 47474022 1198 0
PHF8 Hs68plusFBSGSE20725 47472593 47474113 1520 0
Rb shRbQuiescentGSE19898 47473328 47473529 201 0
TAF k562GSE8489 47472079 47472429 350 0
hScc1 BcellGSE12603 47473020 47473392 372 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018