AutismKB 2.0

Annotation Detail for CFLAR


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Basic Information Top
Gene Symbol:CFLAR ( CASH,CASP8AP1,CLARP,Casper,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,MRIT,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS )
Gene Full Name: CASP8 and FADD-like apoptosis regulator
Band: 2q33.1
Quick LinksEntrez ID:8837; OMIM: 603599; Uniprot ID:CFLAR_HUMAN; ENSEMBL ID: ENSG00000003402; HGNC ID: 1876
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
51Phosphoserine(PKG)HMM predict
126Phosphoserine(PKG)HMM predict
227Phosphoserine(PKG)HMM predict
244Phosphotyrosine(Syk)HMM predict
262N-linkedHMM predict
305Phosphotyrosine(EGFR)HMM predict
305SulfotyrosineHMM predict
318Phosphoserine(PKA)HMM predict
347Phosphotyrosine(Jak)HMM predict
371Phosphoserine(CK1)HMM predict
418Phosphoserine(CK1)HMM predict
418Phosphoserine(IKK)HMM predict
421Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003879
  • Location:chr2 201689134-201737245
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF k562GSE8489 201680942 201681263 321 8032
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 201698674 201698936 262 0
CTCF CD4GSE12889 201731325 201731615 290 0
CTCF CD4SISSRdata 201698674 201698936 262 0
CTCF CD4SISSRdata 201731325 201731615 290 0
CTCF G2GSE9613 201689316 201689920 604 0
CTCF G2GSE9613 201691408 201691903 495 0
CTCF G2GSE9613 201697664 201698220 556 0
CTCF G2GSE9613 201709873 201710264 391 0
CTCF G2GSE9613 201730847 201731652 805 0
CTCF G2GSE9613 201733056 201733325 269 0
Gata2 K562GSE18868 201698416 201698997 581 0
H3K4me3 colorectalcancer 201690372 201690682 310 0
H3K4me3 colorectalcancer 201691026 201692347 1321 0
H3ac HepG2E 201689799 201690682 883 0
H3ac HepG2E 201691026 201692885 1859 0
H3ac HepG2E 201696643 201697258 615 0
H3ac HepG2E 201697604 201698821 1217 0
H3ac HepG2E 201699568 201700316 748 0
NFkBII GM12878GSE19485 201688829 201694572 5743 0
NFkBII GM12878GSE19485 201694727 201704373 9646 0
NFkBII GM12878GSE19485 201730522 201731994 1472 0
NFkBII GM18526GSE19485 201688910 201693169 4259 0
Nanog ESGSE20650 201712464 201712824 360 0
Rb GrowingGSE19898 201735662 201735810 148 0
Rb shRbQuiescentGSE19898 201730689 201730947 258 0
Rb shRbQuiescentGSE19898 201733625 201733882 257 0
TAF k562GSE8489 201690027 201690682 655 0
TAF k562GSE8489 201691625 201692885 1260 0
TAF k562GSE8489 201693273 201694196 923 0
TAF k562GSE8489 201696643 201697258 615 0
TAF k562GSE8489 201697604 201698571 967 0
TFAP2C MCF7GSE21234 201691281 201692410 1129 0
USF1 HepG2E 201729769 201730096 327 0
hScc1 BcellGSE12603 201689281 201690059 778 0
hScc1 BcellGSE12603 201690477 201690682 205 0
hScc1 BcellGSE12603 201691334 201691950 616 0
hScc1 BcellGSE12603 201712940 201713153 213 0
hScc1 BcellGSE12603 201731396 201731652 256 0
hScc1 CdLSGSE12603 201691408 201692063 655 0
hScc1 CdLSGSE12603 201731101 201731652 551 0
p130 QuiescentGSE19898 201689029 201690113 1084 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-512-3p hsa-mir-512-1 19 20372864
hsa-miR-512-3p hsa-mir-512-2 19 20372864
hsa-miR-512-5p hsa-mir-512-1 19 20372864
hsa-miR-512-5p hsa-mir-512-2 19 20372864
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15486 mRNA CFLAR chr2 201806395 201854507 90 mRNA ALS2CR10 chr2 201830517 201848021Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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