AutismKB 2.0

Annotation Detail for IER3


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Basic Information Top
Gene Symbol:IER3 ( DIF-2,DIF2,GLY96,IEX-1,IEX-1L,IEX1,PRG1 )
Gene Full Name: immediate early response 3
Band: 6p21.33
Quick LinksEntrez ID:8870; OMIM: 602996; Uniprot ID:IEX1_HUMAN; ENSEMBL ID: ENSG00000137331; HGNC ID: 5392
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
133N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
18Phosphothreonine (MAPK6)Phospho.ELM 6.0
133N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
12O-linkedHMM predict
18O-linkedHMM predict
18Phosphothreonine(MAPK)HMM predict
18O-linkedHMM predict
22O-linkedHMM predict
31Phosphoserine(PKB)HMM predict
31Phosphoserine(PKC)HMM predict
31Phosphoserine(PKG)HMM predict
53Phosphoserine(PKA)HMM predict
56MethylarginineHMM predict
62Phosphoserine(PKG)HMM predict
123Phosphothreonine(CDC2)HMM predict
123Phosphothreonine(CDK)HMM predict
126Phosphoserine(CDC2)HMM predict
126Phosphoserine(MAPK)HMM predict
133N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003897
  • Location:chr6 30818955-30820302
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30825451 30825733 282 5290
CTCF G2GSE9613 30835535 30835901 366 15416
ER Breast-CancerGSE22609 30827052 30827851 799 7149
ER MCF7GSE19013 30827053 30827815 762 7132
FOXA1 MCF7GSE15244 30823290 30825522 2232 4104
H3ac HepG2E 30821803 30822091 288 1645
H3ac HepG2E 30823084 30825278 2194 3879
H3ac HepG2E 30825663 30826052 389 5555
Oct1 H2O2-HelaGSE14283 30829644 30829725 81 9382
Oct1 HelaGSE14283 30829639 30829736 97 9385
P300 T30-glioblastomaGSE21026 30827288 30829581 2293 8132
RARA MCF7GSE15244 30827231 30828995 1764 7811
RARA MCF7GSE15244 30839884 30840265 381 19772
TAF HelaGSE8489 30840013 30840265 252 19837
TFAP2C MCF7GSE21234 30827849 30828723 874 7984
USF2 HepG2E 30839884 30840265 381 19772
hScc1 BcellGSE12603 30825414 30825733 319 5271
hScc1 BcellGSE12603 30835683 30835901 218 15490
p130 shRbQuiescentGSE19898 30839306 30839781 475 19241
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30818113 30819556 1443 121
TFAP2C MCF7GSE21234 30818522 30819331 809 29
hScc1 BcellGSE12603 30818113 30819335 1222 232
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30819857 30820471 614 0
H3ac HepG2E 30818816 30820547 1731 0
NFkBII GM10847GSE19485 30817309 30820817 3508 0
NFkBII GM12878GSE19485 30817301 30820818 3517 0
Pol2 GM12878GSE19551 30817971 30820601 2630 0
hScc1 BcellGSE12603 30819857 30820547 690 0
hScc1 CdLSGSE12603 30819857 30820512 655 0
hScc1 G2GSE9613 30818113 30820512 2399 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22379 EST chr6 30818769 30819429 440 mRNA IER3 chr6 30818955 30820303Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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