AutismKB 2.0

Annotation Detail for ARHGEF7


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Basic Information Top
Gene Symbol:ARHGEF7 ( BETA-PIX,COOL-1,COOL1,DKFZp686C12170,DKFZp761K1021,KIAA0142,KIAA0412,Nbla10314,P50,P50BP,P85,P85COOL1,P85SPR,PAK3,PIXB )
Gene Full Name: Rho guanine nucleotide exchange factor (GEF) 7
Band: 13q34
Quick LinksEntrez ID:8874; OMIM: 605477; Uniprot ID:ARHG7_HUMAN; ENSEMBL ID: ENSG00000102606; HGNC ID: 15607
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
153Phosphoserine (By similarity).
176Phosphoserine.
249Phosphoserine.
518Phosphoserine.
694Phosphoserine.
Location(AA) Modifications Resource
176Phosphoserine (By similarity).Swiss-Prot 53.0
249Phosphoserine.Swiss-Prot 53.0
518Phosphoserine.Swiss-Prot 53.0
694Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
19Phosphoserine(CDC2)HMM predict
62Phosphoserine(IKK)HMM predict
64Phosphoserine(CK2)HMM predict
64Phosphoserine(PKB)HMM predict
64Phosphoserine(IKK)HMM predict
90Phosphoserine(ATM)HMM predict
206Phosphoserine(CK1)HMM predict
244Phosphoserine(PKG)HMM predict
249Phosphoserine(CDC2)HMM predict
249Phosphoserine(MAPK)HMM predict
254Phosphothreonine(PKC)HMM predict
257Phosphoserine(CDC2)HMM predict
268N-linkedHMM predict
273N-linkedHMM predict
286SulfotyrosineHMM predict
287Phosphoserine(CK1)HMM predict
303Phosphothreonine(PKC)HMM predict
359Phosphothreonine(Jak)HMM predict
393Phosphoserine(CDC2)HMM predict
479N-linkedHMM predict
514Phosphoserine(CDK)HMM predict
580Phosphothreonine(PKA)HMM predict
580O-linkedHMM predict
584N-linkedHMM predict
599O-linkedHMM predict
603Phosphothreonine(CDK)HMM predict
603Phosphothreonine(MAPK)HMM predict
603Phosphothreonine(CDC2)HMM predict
605Phosphoserine(MAPK)HMM predict
617Phosphothreonine(MAPK)HMM predict
622Phosphothreonine(CDK)HMM predict
627O-linkedHMM predict
631Phosphothreonine(CDK)HMM predict
646Phosphothreonine(MAPK)HMM predict
676Phosphoserine(CDC2)HMM predict
679Phosphothreonine(PKC)HMM predict
694Phosphoserine(PKG)HMM predict
694Phosphoserine(PKA)HMM predict
704Phosphothreonine(PKA)HMM predict
729Phosphothreonine(PKA)HMM predict
731N-linkedHMM predict
761Phosphoserine(CAMK2)HMM predict
761Phosphoserine(PKG)HMM predict
771Phosphoserine(CK1)HMM predict
771Phosphoserine(CK2)HMM predict
774Phosphoserine(CK1)HMM predict
776Phosphotyrosine(INSR)HMM predict
776Phosphotyrosine(Syk)HMM predict
776Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003899
  • Location:chr13 110604085-110756078
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARA MCF7GSE15244 110757535 110758594 1059 1986
RARA MCF7GSE15244 110760327 110761840 1513 5005
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 110626399 110629313 2914 0
CTCF CD4GSE12889 110666668 110666857 189 0
CTCF CD4GSE12889 110673808 110674129 321 0
CTCF CD4SISSRdata 110666668 110666857 189 0
CTCF CD4SISSRdata 110673808 110674129 321 0
CTCF G2GSE9613 110666628 110667143 515 0
CTCF G2GSE9613 110671004 110671227 223 0
CTCF G2GSE9613 110678870 110679211 341 0
CTCF G2GSE9613 110733466 110733733 267 0
H3ac HepG2E 110604574 110605166 592 0
Oct1 HelaGSE14283 110689305 110689332 27 0
PHF8 Hs68plusFBSGSE20725 110603257 110604920 1663 0
RARA MCF7GSE15244 110704774 110705554 780 0
Rb GrowingGSE19898 110716042 110716178 136 0
Stat6 IL-4-hr1GSE17850 110712920 110713452 532 0
TFAP2C MCF7GSE21234 110604418 110604871 453 0
hScc1 BcellGSE12603 110666628 110667246 618 0
hScc1 BcellGSE12603 110673807 110674180 373 0
hScc1 BcellGSE12603 110733363 110733697 334 0
hScc1 CdLSGSE12603 110666628 110667143 515 0
hScc1 CdLSGSE12603 110673807 110674180 373 0
p130 shRbSenescentGSE19898 110748284 110748415 131 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7526 mRNA ARHGEF7 chr13 110565782 110745543 132 EST chr13 110564621 110566026Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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