AutismKB 2.0

Annotation Detail for PRPF4B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PRPF4B ( KIAA0536,PR4H,PRP4,PRP4H,PRP4K,dJ1013A10.1 )
Gene Full Name: PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Band: 6p25.2
Quick LinksEntrez ID:8899; OMIM: 602338; Uniprot ID:PRP4B_HUMAN; ENSEMBL ID: ENSG00000112739; HGNC ID: 17346
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
6Phosphothreonine.
8Phosphoserine.
20Phosphoserine.
23Phosphoserine.
32Phosphoserine.
36Phosphoserine.
87Phosphoserine.
93Phosphoserine.
140Phosphotyrosine.
142Phosphoserine.
144Phosphoserine.
239Phosphoserine.
241Phosphoserine.
257Phosphoserine.
277Phosphoserine.
292Phosphoserine.
294Phosphoserine.
328Phosphoserine.
354Phosphoserine.
356Phosphoserine.
358N6-acetyllysine.
366Phosphoserine.
368Phosphoserine.
381Phosphoserine.
385Phosphothreonine.
387Phosphoserine.
410Phosphoserine.
411Phosphoserine.
427Phosphoserine.
431Phosphoserine.
437Phosphoserine.
518Phosphoserine.
519Phosphoserine.
520Phosphoserine.
569Phosphoserine.
576Phosphothreonine.
578Phosphoserine.
580Phosphoserine.
717N6-acetyllysine.
849Phosphotyrosine.
852Phosphoserine (By similarity).
Location(AA) Modifications Resource
20Phosphoserine.Swiss-Prot 53.0
20PhosphoserinePhospho.ELM 6.0
23Phosphoserine.Swiss-Prot 53.0
23PhosphoserinePhospho.ELM 6.0
32Phosphoserine.Swiss-Prot 53.0
32PhosphoserinePhospho.ELM 6.0
36Phosphoserine.Swiss-Prot 53.0
36PhosphoserinePhospho.ELM 6.0
87Phosphoserine.Swiss-Prot 53.0
87PhosphoserinePhospho.ELM 6.0
93PhosphoserinePhospho.ELM 6.0
93Phosphoserine.Swiss-Prot 53.0
142PhosphoserinePhospho.ELM 6.0
144PhosphoserinePhospho.ELM 6.0
239Phosphoserine.Swiss-Prot 53.0
239PhosphoserinePhospho.ELM 6.0
241PhosphoserinePhospho.ELM 6.0
241Phosphoserine.Swiss-Prot 53.0
257Phosphoserine.Swiss-Prot 53.0
257PhosphoserinePhospho.ELM 6.0
277Phosphoserine.Swiss-Prot 53.0
277PhosphoserinePhospho.ELM 6.0
292PhosphoserinePhospho.ELM 6.0
292Phosphoserine.Swiss-Prot 53.0
294Phosphoserine.Swiss-Prot 53.0
294PhosphoserinePhospho.ELM 6.0
328Phosphoserine.Swiss-Prot 53.0
328PhosphoserinePhospho.ELM 6.0
354PhosphoserinePhospho.ELM 6.0
354Phosphoserine.Swiss-Prot 53.0
356Phosphoserine.Swiss-Prot 53.0
356PhosphoserinePhospho.ELM 6.0
366PhosphoserinePhospho.ELM 6.0
366Phosphoserine.Swiss-Prot 53.0
368Phosphoserine.Swiss-Prot 53.0
368PhosphoserinePhospho.ELM 6.0
381Phosphoserine.Swiss-Prot 53.0
385Phosphothreonine.Swiss-Prot 53.0
387PhosphoserinePhospho.ELM 6.0
387Phosphoserine.Swiss-Prot 53.0
410PhosphoserinePhospho.ELM 6.0
410Phosphoserine.Swiss-Prot 53.0
411Phosphoserine.Swiss-Prot 53.0
411PhosphoserinePhospho.ELM 6.0
427Phosphoserine (By similarity).Swiss-Prot 53.0
431Phosphoserine.Swiss-Prot 53.0
431PhosphoserinePhospho.ELM 6.0
437Phosphoserine.Swiss-Prot 53.0
437PhosphoserinePhospho.ELM 6.0
443PhosphoserinePhospho.ELM 6.0
445PhosphoserinePhospho.ELM 6.0
458PhosphoserinePhospho.ELM 6.0
460PhosphoserinePhospho.ELM 6.0
569PhosphoserinePhospho.ELM 6.0
569Phosphoserine.Swiss-Prot 53.0
576Phosphothreonine.Swiss-Prot 53.0
576PhosphothreoninePhospho.ELM 6.0
578Phosphoserine.Swiss-Prot 53.0
578PhosphoserinePhospho.ELM 6.0
580Phosphoserine.Swiss-Prot 53.0
580PhosphoserinePhospho.ELM 6.0
849Phosphotyrosine.Swiss-Prot 53.0
849PhosphotyrosinePhospho.ELM 6.0
852Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
20Phosphoserine(CK1)HMM predict
20Phosphoserine(CK2)HMM predict
32PhosphoserineHMM predict
36Phosphoserine(ATM)HMM predict
60Phosphoserine(CK1)HMM predict
60Phosphoserine(CK2)HMM predict
60PhosphoserineHMM predict
61Phosphoserine(CK2)HMM predict
93Phosphoserine(CDC2)HMM predict
142Phosphoserine(CK2)HMM predict
142Phosphoserine(CK2)HMM predict
142Phosphoserine(ATM)HMM predict
144PhosphoserineHMM predict
158N-linkedHMM predict
160Phosphoserine(CDC2)HMM predict
162Phosphothreonine(PKC)HMM predict
165Phosphoserine(CDC2)HMM predict
180Phosphothreonine(PKC)HMM predict
188Phosphoserine(CK1)HMM predict
212Phosphothreonine(PKC)HMM predict
223Phosphoserine(PKG)HMM predict
223Phosphoserine(IKK)HMM predict
225Phosphoserine(CDC2)HMM predict
225PhosphoserineHMM predict
232Phosphoserine(PKA)HMM predict
232Phosphoserine(ATM)HMM predict
232Phosphoserine(IKK)HMM predict
239Phosphoserine(PKG)HMM predict
241Phosphoserine(CDC2)HMM predict
241Phosphoserine(CDK)HMM predict
243Phosphothreonine(PKC)HMM predict
248Phosphoserine(PKC)HMM predict
248Phosphoserine(PKG)HMM predict
259Phosphothreonine(PKC)HMM predict
277Phosphoserine(CDC2)HMM predict
281N-linkedHMM predict
292Phosphoserine(PKG)HMM predict
319Phosphothreonine(PKC)HMM predict
328Phosphoserine(CDC2)HMM predict
328PhosphoserineHMM predict
335Phosphoserine(CK1)HMM predict
339N-linkedHMM predict
341Phosphoserine(CDC2)HMM predict
341PhosphoserineHMM predict
343PhosphoserineHMM predict
349Phosphoserine(CDC2)HMM predict
354Phosphoserine(PKG)HMM predict
356Phosphoserine(CDC2)HMM predict
356Phosphoserine(CDK)HMM predict
366Phosphoserine(PKA)HMM predict
366Phosphoserine(PKG)HMM predict
368Phosphoserine(CDC2)HMM predict
368Phosphoserine(IKK)HMM predict
376Phosphoserine(CDK)HMM predict
379Phosphoserine(PKG)HMM predict
381Phosphoserine(CDC2)HMM predict
381Phosphoserine(CDK)HMM predict
381Phosphoserine(IKK)HMM predict
387Phosphoserine(CDC2)HMM predict
387PhosphoserineHMM predict
394Phosphoserine(PKG)HMM predict
396Phosphoserine(CK1)HMM predict
410Phosphoserine(PKC)HMM predict
410Phosphoserine(PKG)HMM predict
410PhosphoserineHMM predict
411Phosphoserine(CDC2)HMM predict
411PhosphoserineHMM predict
427Phosphoserine(CAMK2)HMM predict
427Phosphoserine(PKB)HMM predict
439Phosphothreonine(PKC)HMM predict
443Phosphoserine(PKC)HMM predict
443Phosphoserine(PKG)HMM predict
445Phosphoserine(CDC2)HMM predict
445Phosphoserine(CDK)HMM predict
451Phosphoserine(PKG)HMM predict
451PhosphoserineHMM predict
453Phosphoserine(CDC2)HMM predict
453Phosphoserine(CDK)HMM predict
458Phosphoserine(PKA)HMM predict
460Phosphoserine(CDC2)HMM predict
460Phosphoserine(CDK)HMM predict
465Phosphoserine(PKG)HMM predict
467Phosphoserine(CDC2)HMM predict
467Phosphoserine(CDK)HMM predict
477Phosphoserine(PKA)HMM predict
485Phosphoserine(PKG)HMM predict
485PhosphoserineHMM predict
495Phosphoserine(PKG)HMM predict
495PhosphoserineHMM predict
497Phosphoserine(PKB)HMM predict
519Phosphoserine(CK1)HMM predict
520Phosphoserine(CK1)HMM predict
520Phosphoserine(CK2)HMM predict
560N-linkedHMM predict
562Phosphoserine(CK1)HMM predict
565O-linkedHMM predict
568Phosphoserine(CK1)HMM predict
569Phosphoserine(CDC2)HMM predict
569Phosphoserine(ATM)HMM predict
572Phosphoserine(IKK)HMM predict
574O-linkedHMM predict
578Phosphoserine(CDC2)HMM predict
578Phosphoserine(IKK)HMM predict
578PhosphoserineHMM predict
580Phosphoserine(ATM)HMM predict
620N-linkedHMM predict
622Phosphoserine(CDC2)HMM predict
667N-linkedHMM predict
674Phosphotyrosine(Syk)HMM predict
824N-linkedHMM predict
868SulfotyrosineHMM predict
931Phosphotyrosine(Jak)HMM predict
938Phosphothreonine(PKC)HMM predict
944Phosphothreonine(PKC)HMM predict
950N-linkedHMM predict
992IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003913
  • Location:chr6 3966567-4010214
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3953662 3953981 319 12746
CTCF CD4SISSRdata 3953662 3953981 319 12746
CTCF G2GSE9613 3953642 3953859 217 12817
CTCF G2GSE9613 3963456 3964058 602 2811
FoxA1 MCF7MACSdata 3953511 3953850 339 12887
GABP k562GSE8489 3965883 3966322 439 465
H3K4me2 HCT116GSE10453 3965883 3966322 439 465
H3K4me3 colorectalcancer 3962765 3963592 827 3389
H3K4me3 colorectalcancer 3965347 3965513 166 1138
H3K4me3 colorectalcancer 3965883 3966429 546 412
H3ac HepG2E 3961149 3961512 363 5237
H3ac HepG2E 3962451 3963528 1077 3578
H3ac HepG2E 3964021 3964773 752 2171
H3ac HepG2E 3965347 3965513 166 1138
Oct1 HelaGSE14283 3954968 3954996 28 11586
Oct1 HelaGSE14283 3955027 3955055 28 11527
P300 T30-glioblastomaGSE21026 3953432 3954077 645 12813
PHF8 HeLaGSE20725 3963169 3964474 1305 2746
RARA MCF7GSE15244 3953376 3954004 628 12878
TAF HelaGSE8489 3962729 3963308 579 3549
TAF k562GSE8489 3961149 3961794 645 5096
TAF k562GSE8489 3962451 3963416 965 3634
TAF k562GSE8489 3964129 3964773 644 2117
TAF k562GSE8489 3965347 3965513 166 1138
TAF k562GSE8489 3965883 3966644 761 304
TFAP2C MCF7GSE21234 3963578 3964363 785 2597
hScc1 BcellGSE12603 3963592 3963927 335 2808
hScc1 CdLSGSE12603 3953351 3954035 684 12875
hScc1 G2GSE9613 3953642 3953968 326 12763
p130 shRbQuiescentGSE19898 3963489 3964197 708 2725
p130 shRbSenescentGSE19898 3963401 3964371 970 2682
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3966739 3967039 300 0
CTCF CD4SISSRdata 3966739 3967039 300 0
CTCF HelaGSE12889 3966913 3967041 128 0
CTCF G2GSE9613 3966459 3966885 426 0
ETS1 JurkatGSE17954 3966014 3967298 1284 0
Fos K562GSE19551 4000675 4001126 451 0
H3ac HepG2E 3965883 3968512 2629 0
KLF4 hESGSE17917 3972730 3972984 254 0
Myc K562GSE19551 4000629 4001019 390 0
TAF HelaGSE8489 3967136 3968290 1154 0
TAF k562GSE8489 3967053 3968897 1844 0
TAF k562GSE8489 3974899 3975137 238 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved