AutismKB 2.0

Annotation Detail for TIMELESS


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Basic Information Top
Gene Symbol:TIMELESS ( FLJ12640,FLJ20714,TIM,TIM1,hTIM )
Gene Full Name: timeless homolog (Drosophila)
Band: 12q13.3
Quick LinksEntrez ID:8914; OMIM: 603887; Uniprot ID:TIM_HUMAN; ENSEMBL ID: ENSG00000111602; HGNC ID: 11813
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
299N6-acetyllysine.
1089Phosphothreonine.
1149Phosphoserine.
1173Phosphoserine.
Location(AA) Modifications Resource
1173Phosphoserine.Swiss-Prot 53.0
1173PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
19Phosphotyrosine(Jak)HMM predict
25Phosphotyrosine(EGFR)HMM predict
88N-linkedHMM predict
105Phosphoserine(PKC)HMM predict
138Phosphotyrosine(SRC)HMM predict
207Phosphoserine(CK2)HMM predict
209Phosphoserine(CK2)HMM predict
378SulfotyrosineHMM predict
414N-linkedHMM predict
417N-linkedHMM predict
418SulfotyrosineHMM predict
419SulfotyrosineHMM predict
419Phosphotyrosine(Syk)HMM predict
456Phosphoserine(ATM)HMM predict
552Phosphoserine(CDC2)HMM predict
638Phosphoserine(ATM)HMM predict
807SulfotyrosineHMM predict
815Phosphoserine(CK1)HMM predict
821PhosphothreonineHMM predict
884Phosphothreonine(PKA)HMM predict
917N-linkedHMM predict
982PhosphoserineHMM predict
982Phosphoserine(CK1)HMM predict
990Phosphoserine(CK2)HMM predict
1039Phosphoserine(ATM)HMM predict
1074Phosphoserine(CDK)HMM predict
1097Phosphoserine(IKK)HMM predict
1099Phosphoserine(ATM)HMM predict
1099Phosphoserine(CK2)HMM predict
1121Phosphoserine(CK2)HMM predict
1121Phosphoserine(CK2)HMM predict
1149Phosphoserine(MAPK)HMM predict
1173Phosphoserine(CK2)HMM predict
1173Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003920
  • Location:chr12 55097174-55129432
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF HelaGSE8489 55128809 55130752 1943 348
TAF k562GSE8489 55128809 55130146 1337 45
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 55086910 55086943 33 10248
Oct1 HelaGSE14283 55093150 55093209 59 3995
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 55128809 55129454 645 0
E2F4 G0GSE7516 55128809 55129593 784 0
ER E2-MCF7GSE14664 55107099 55107134 35 0
FOXA1 MCF7GSE15244 55129053 55129693 640 0
H3K4me3 colorectalcancer 55128809 55129017 208 0
H3ac HepG2E 55128809 55129186 377 0
LIN9 G0GSE7516 55128809 55129669 860 0
LIN9 SGSE7516 55128809 55129816 1007 0
Myc K562GSE19551 55117568 55118127 559 0
Oct1 H2O2-HelaGSE14283 55122883 55122917 34 0
PHF8 293TGSE20725 55128847 55129950 1103 0
Rb GrowingGSE19898 55129086 55129378 292 0
Rb QuiescentGSE19898 55128865 55129526 661 0
Rb SenescentGSE19898 55128781 55129633 852 0
Rb shRbSenescenceGSE19898 55128986 55129567 581 0
TAF HelaGSE8489 55124845 55125140 295 0
TFAP2C MCF7GSE21234 55123313 55123671 358 0
USF2 HepG2E 55128809 55129186 377 0
p130 QuiescentGSE19898 55128917 55129668 751 0
p130 SenescentGSE19898 55128789 55129723 934 0
p130 shRbQuiescentGSE19898 55128973 55129725 752 0
p130 shRbSenescentGSE19898 55128887 55129743 856 0
p130 G0GSE7516 55128879 55129669 790 0
p130 SGSE7516 55128809 55129816 1007 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018