AutismKB 2.0

Annotation Detail for SKAP2


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Basic Information Top
Gene Symbol:SKAP2 ( MGC10411,MGC33304,PRAP,RA70,SAPS,SCAP2,SKAP-HOM,SKAP55R )
Gene Full Name: src kinase associated phosphoprotein 2
Band: 7p15.2
Quick LinksEntrez ID:8935; OMIM: 605215; Uniprot ID:SKAP2_HUMAN; ENSEMBL ID: ENSG00000005020; HGNC ID: 15687
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
75Phosphotyrosine (By similarity).
151Phosphotyrosine.
197Phosphotyrosine.
261Phosphotyrosine (By similarity).
325Phosphotyrosine.
Location(AA) Modifications Resource
75Phosphotyrosine (By similarity).Swiss-Prot 53.0
197Phosphotyrosine (By similarity).Swiss-Prot 53.0
261Phosphotyrosine (By similarity).Swiss-Prot 53.0
325Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
7O-linkedHMM predict
7O-linkedHMM predict
9Phosphoserine(CDC2)HMM predict
9O-linkedHMM predict
59Phosphotyrosine(EGFR)HMM predict
75Phosphotyrosine(INSR)HMM predict
75PhosphotyrosineHMM predict
75SulfotyrosineHMM predict
75Phosphotyrosine(Syk)HMM predict
93Phosphotyrosine(Syk)HMM predict
101Phosphoserine(CK1)HMM predict
152SulfotyrosineHMM predict
174N-linkedHMM predict
175N-linkedHMM predict
230Phosphotyrosine(Syk)HMM predict
237SulfotyrosineHMM predict
253Phosphoserine(ATM)HMM predict
261SulfotyrosineHMM predict
261PhosphotyrosineHMM predict
261Phosphotyrosine(EGFR)HMM predict
261Phosphotyrosine(Syk)HMM predict
283Phosphoserine(PKA)HMM predict
298Phosphotyrosine(Syk)HMM predict
298Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003930
  • Location:chr7 26673214-26870865
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 26870742 26871092 350 52
Oct1 HelaGSE14283 26878391 26878421 30 7541
P300 T30-glioblastomaGSE21026 26870503 26871392 889 82
PHF8 Hs68minusFBSGSE20725 26870907 26871381 474 279
TAF HelaGSE8489 26871244 26871604 360 559
USF2 HepG2E 26870245 26871604 1359 59
p130 QuiescentGSE19898 26870834 26871216 382 160
p130 SenescentGSE19898 26870536 26871309 773 57
p130 shRbQuiescentGSE19898 26870448 26871508 1060 113
p130 shRbSenescentGSE19898 26870787 26871364 577 210
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 26658884 26659634 750 13956
FOXA1 MCF7GSE15244 26658782 26660207 1425 13720
FOXA1 MCF7GSE15244 26664213 26665083 870 8567
RARA MCF7GSE15244 26658985 26660431 1446 13507
TFAP2C MCF7GSE21234 26668833 26669318 485 4139
TFAP2C MCF7GSE21234 26670992 26671471 479 1983
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 26673735 26674100 365 0
CTCF CD4SISSRdata 26673735 26674100 365 0
CTCF G2GSE9613 26673592 26674126 534 0
ER E2-MCF7GSE14664 26797133 26797205 72 0
ER E2-MCF7GSE14664 26842078 26842110 32 0
ER Fulvestrant-MCF7GSE14664 26842074 26842109 35 0
ER MCF7GSE19013 26695585 26696297 712 0
Fos K562GSE19551 26856257 26856971 714 0
FoxA1 MCF7MACSdata 26694563 26694715 152 0
Myc K562GSE19551 26673674 26674020 346 0
Myc K562GSE19551 26695220 26695658 438 0
Nanog hESGSE18292 26790196 26790654 458 0
Oct1 H2O2-HelaGSE14283 26859374 26859414 40 0
Oct1 H2O2-HelaGSE14283 26859869 26859923 54 0
Oct1 HelaGSE14283 26845845 26845936 91 0
Oct1 HelaGSE14283 26859374 26859413 39 0
Oct1 HelaGSE14283 26859869 26859926 57 0
P300 T30-glioblastomaGSE21026 26711791 26712360 569 0
RARA MCF7GSE15244 26694114 26696336 2222 0
Sox2 hESGSE18292 26790193 26790757 564 0
TFAP2C MCF7GSE21234 26870353 26871181 828 0
USF1 HepG2E 26869339 26871604 2265 0
hScc1 BcellGSE12603 26673675 26674053 378 0
hScc1 BcellGSE12603 26692509 26692860 351 0
hScc1 CdLSGSE12603 26673525 26674089 564 0
hScc1 CdLSGSE12603 26692545 26693015 470 0
hScc1 G2GSE9613 26673525 26674126 601 0
p130 shRbSenescentGSE19898 26673751 26673977 226 0
p63 keratinocytesGSE17611 26804853 26805623 770 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16-1* hsa-mir-16-1 13 18362358
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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