Annotation Detail for KYNU
Basic Information Top
| Gene Symbol: | KYNU ( - ) |
|---|---|
| Gene Full Name: | kynureninase (L-kynurenine hydrolase) |
| Band: | 2q22.2 |
| Quick Links | Entrez ID:8942; OMIM: 605197; Uniprot ID:KYNU_HUMAN; ENSEMBL ID: ENSG00000115919; HGNC ID: 6469 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 1 | N-acetylmethionine (By similarity). | |
| 276 | N6-(pyridoxal phosphate)lysine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 1 | N-acetylmethionine (By similarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 353 | Phosphothreonine(PKC) | HMM predict |
| 383 | Phosphothreonine(PKC) | HMM predict |
- RefSeq ID: NM_001032998
- Location:chr2 143351664-143463573
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | T30-glioblastoma | GSE21026 | 143346917 | 143349081 | 2164 | 3666 |
| FOXA1 | MCF7 | GSE15244 | 143331642 | 143332075 | 433 | 19806 |
| FOXA1 | MCF7 | GSE15244 | 143337648 | 143338029 | 381 | 13826 |
| FOXA1 | MCF7 | GSE15244 | 143348001 | 143348922 | 921 | 3203 |
| FoxA1 | MCF7 | MACSdata | 143337608 | 143337944 | 336 | 13889 |
| FoxA1 | MCF7 | MACSdata | 143348451 | 143348797 | 346 | 3041 |
| Oct1 | H2O2-Hela | GSE14283 | 143350250 | 143350302 | 52 | 1389 |
| Oct1 | Hela | GSE14283 | 143350250 | 143350299 | 49 | 1390 |
| P300 | T30-glioblastoma | GSE21026 | 143331392 | 143332458 | 1066 | 19740 |
| P300 | T30-glioblastoma | GSE21026 | 143346811 | 143350604 | 3793 | 2957 |
| PolII | HeLa | GSE12783 | 143346469 | 143356642 | 10173 | 109 |
| STAT1 | HeLa | GSE12783 | 143335999 | 143337370 | 1371 | 14980 |
| STAT1 | HeLa | GSE12783 | 143346970 | 143350172 | 3202 | 3094 |
| TFAP2C | MCF7 | GSE21234 | 143348178 | 143349005 | 827 | 3073 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ER | Fulvestrant-MCF7 | GSE14664 | 143359043 | 143359080 | 37 | 0 |
| FOXA1 | MCF7 | GSE15244 | 143417802 | 143418785 | 983 | 0 |
| FOXA1 | MCF7 | GSE15244 | 143454552 | 143454776 | 224 | 0 |
| FoxA1 | MCF7 | MACSdata | 143418311 | 143418587 | 276 | 0 |
| FoxA1 | MCF7 | MACSdata | 143418726 | 143418898 | 172 | 0 |
| Myc | K562 | GSE19551 | 143412293 | 143412573 | 280 | 0 |
| Nanog | ES | GSE20650 | 143388759 | 143389117 | 358 | 0 |
| Nanog | hES | GSE18292 | 143448449 | 143449065 | 616 | 0 |
| Nanog | hES | GSE18292 | 143454890 | 143455213 | 323 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 143359028 | 143359058 | 30 | 0 |
| Oct1 | Hela | GSE14283 | 143359030 | 143359080 | 50 | 0 |
| Oct1 | Hela | GSE14283 | 143436501 | 143436530 | 29 | 0 |
| Oct4 | hES | GSE21916 | 143448453 | 143448770 | 317 | 0 |
| PolII | HeLa | GSE12783 | 143359055 | 143370955 | 11900 | 0 |
| PolII | HeLa | GSE12783 | 143393948 | 143405842 | 11894 | 0 |
| Sox2 | hES | GSE18292 | 143448441 | 143448814 | 373 | 0 |
| TAF | Hela | GSE8489 | 143353240 | 143353839 | 599 | 0 |
| TFAP2C | MCF7 | GSE21234 | 143377555 | 143378292 | 737 | 0 |
| TFAP2C | MCF7 | GSE21234 | 143448337 | 143448941 | 604 | 0 |
| USF2 | HepG2 | E | 143425569 | 143425895 | 326 | 0 |
| hScc1 | Bcell | GSE12603 | 143463238 | 143463476 | 238 | 0 |
| hScc1 | CdLS | GSE12603 | 143463131 | 143463679 | 548 | 0 |
Validated miRNA targets