AutismKB 2.0

Annotation Detail for BTRC


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Basic Information Top
Gene Symbol:BTRC ( BETA-TRCP,FBW1A,FBXW1,FBXW1A,FWD1,MGC4643,bTrCP,bTrCP1,betaTrCP )
Gene Full Name: beta-transducin repeat containing
Band: 10q24.32
Quick LinksEntrez ID:8945; OMIM: 603482; Uniprot ID:FBW1A_HUMAN; ENSEMBL ID: ENSG00000166167; HGNC ID: 1144
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
33Phosphoserine(IKK)HMM predict
53N-linkedHMM predict
113N-linkedHMM predict
127Phosphoserine(PKG)HMM predict
127Phosphoserine(PKA)HMM predict
145Phosphoserine(IKK)HMM predict
147PhosphoserineHMM predict
452N-linkedHMM predict
595Phosphoserine(CDC2)HMM predict
596ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003939
  • Location:chr10 103103814-103307057
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 103103005 103104359 1354 133
P300 T30-glioblastomaGSE21026 103103042 103104402 1360 93
RARA MCF7GSE15244 103103352 103103757 405 260
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 103309960 103310450 490 3148
hScc1 BcellGSE12603 103310602 103311030 428 3759
p63 keratinocytesGSE17611 103307601 103308576 975 1031
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 103114419 103114945 526 0
CBP T30-glioblastomaGSE21026 103114394 103114917 523 0
CTCF CD4GSE12889 103192037 103192279 242 0
CTCF CD4GSE12889 103286653 103286878 225 0
CTCF CD4SISSRdata 103192037 103192279 242 0
CTCF CD4SISSRdata 103286653 103286878 225 0
Fos K562GSE19551 103117247 103117841 594 0
Fos K562GSE19551 103144429 103145058 629 0
FoxA1 MCF7MACSdata 103104514 103104685 171 0
Gata2 K562GSE18868 103302216 103302631 415 0
H3K4me3 colorectalcancer 103104324 103105049 725 0
H3ac HepG2E 103104214 103105514 1300 0
Myc K562GSE19551 103114489 103114739 250 0
Myc K562GSE19551 103217110 103217326 216 0
NFkBII GM18526GSE19485 103114248 103114847 599 0
Nanog ESGSE20650 103122820 103123280 460 0
Nanog hESGSE18292 103122839 103123159 320 0
Oct1 H2O2-HelaGSE14283 103169258 103169291 33 0
Oct1 H2O2-HelaGSE14283 103242437 103242468 31 0
Oct1 HelaGSE14283 103127321 103127374 53 0
Oct1 HelaGSE14283 103133738 103133812 74 0
Oct1 HelaGSE14283 103169258 103169289 31 0
Oct1 HelaGSE14283 103169910 103169945 35 0
Oct1 HelaGSE14283 103234138 103234166 28 0
Oct1 HelaGSE14283 103242401 103242467 66 0
P300 T0-glioblastomaGSE21026 103114399 103114851 452 0
P300 T30-glioblastomaGSE21026 103108356 103109356 1000 0
P300 T30-glioblastomaGSE21026 103114443 103115128 685 0
PHF8 293TGSE20725 103114102 103114845 743 0
RARA MCF7GSE15244 103113803 103114149 346 0
RARA MCF7GSE15244 103191741 103192253 512 0
RARA MCF7GSE15244 103203363 103203543 180 0
RARG MCF7GSE15244 103191877 103192185 308 0
Sox2 hESGSE18292 103122923 103123169 246 0
hScc1 BcellGSE12603 103170046 103170218 172 0
hScc1 BcellGSE12603 103191945 103192222 277 0
hScc1 CdLSGSE12603 103191658 103192390 732 0
hScc1 CdLSGSE12603 103217023 103217384 361 0
hScc1 G2GSE9613 103191877 103192297 420 0
p63 keratinocytesGSE17611 103144232 103145232 1000 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-10a hsa-mir-10a 17 20624982
hsa-miR-10a* hsa-mir-10a 17 20624982
hsa-miR-183 hsa-mir-183 7 19647520
hsa-miR-183 hsa-mir-183 7 19647510
hsa-miR-183* hsa-mir-183 7 19647520
hsa-miR-183* hsa-mir-183 7 19647510
hsa-miR-920 hsa-mir-920 12 19931512
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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