AutismKB 2.0

Annotation Detail for CCNE1


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Basic Information Top
Gene Symbol:CCNE1 ( CCNE )
Gene Full Name: cyclin E1
Band: 19q12
Quick LinksEntrez ID:898; OMIM: 123837; Uniprot ID:CCNE1_HUMAN; ENSEMBL ID: ENSG00000105173; HGNC ID: 1589
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
59Phosphoserine.
77Phosphothreonine.
100Phosphoserine.
103Phosphoserine.
381Phosphoserine.
387Phosphoserine.
395Phosphothreonine; by GSK3.
399Phosphoserine; by CDK2.
Location(AA) Modifications Resource
77Phosphothreonine.Swiss-Prot 53.0
77PhosphothreoninePhospho.ELM 6.0
103PhosphoserinePhospho.ELM 6.0
387Phosphoserine.Swiss-Prot 53.0
387PhosphoserinePhospho.ELM 6.0
395Phosphothreonine (by GSK3).Swiss-Prot 53.0
395Phosphothreonine (GSK-3beta;CD)Phospho.ELM 6.0
399Phosphoserine (by CDK2).Swiss-Prot 53.0
399Phosphoserine (CDK2)Phospho.ELM 6.0
Location(AA) Modification Resource
15Phosphothreonine(CK2)HMM predict
34N-linkedHMM predict
59Phosphoserine(ATM)HMM predict
89N-linkedHMM predict
103Phosphoserine(CDC2)HMM predict
222Phosphoserine(CK2)HMM predict
242Phosphoserine(CDC2)HMM predict
362Phosphothreonine(PKC)HMM predict
387Phosphoserine(MAPK)HMM predict
387Phosphoserine(CDC2)HMM predict
395Phosphothreonine(MAPK)HMM predict
395PhosphothreonineHMM predict
399Phosphoserine(CDK)HMM predict
405Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001238
  • Location:chr19 34994740-35007057
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 34993875 34994246 371 680
Fos K562GSE19551 34988770 34989291 521 5710
Oct1 H2O2-HelaGSE14283 34975990 34976028 38 18732
Oct1 HelaGSE14283 34975990 34976026 36 18733
Rb QuiescentGSE19898 34981922 34982115 193 12722
p130 QuiescentGSE19898 34994645 34994804 159 16
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 34994694 34995299 605 0
hScc1 BcellGSE12603 34994694 34995419 725 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-103 hsa-mir-103-2 20 20886090
hsa-miR-103 hsa-mir-103-1 5 20886090
hsa-miR-155 hsa-mir-155 21 19956200
hsa-miR-155* hsa-mir-155 21 19956200
hsa-miR-15a hsa-mir-15a 13 19591824
hsa-miR-15a* hsa-mir-15a 13 19591824
hsa-miR-15b hsa-mir-15b 3 19135980
hsa-miR-15b hsa-mir-15b 3 18794849
hsa-miR-15b* hsa-mir-15b 3 19135980
hsa-miR-15b* hsa-mir-15b 3 18794849
hsa-miR-16 hsa-mir-16-1 13 19944013
hsa-miR-16 hsa-mir-16-2 3 19944013
hsa-miR-16 hsa-mir-16-1 13 18701644
hsa-miR-16 hsa-mir-16-2 3 18701644
hsa-miR-16 hsa-mir-16-1 13 19591824
hsa-miR-16 hsa-mir-16-2 3 19591824
hsa-miR-16-1* hsa-mir-16-1 13 19944013
hsa-miR-195 hsa-mir-195 17 18701644
hsa-miR-195* hsa-mir-195 17 18701644
hsa-miR-21 hsa-mir-21 17 18794849
hsa-miR-21* hsa-mir-21 17 18794849
hsa-miR-222 hsa-mir-222 X 19956200
hsa-miR-222* hsa-mir-222 X 19956200
hsa-miR-424 hsa-mir-424 X 19956200
hsa-miR-424 hsa-mir-424 X 18701644
hsa-miR-424* hsa-mir-424 X 19956200
hsa-miR-424* hsa-mir-424 X 18701644
hsa-miR-503 hsa-mir-503 X 21220732
hsa-miR-503 hsa-mir-503 X 19956200
hsa-miR-9 hsa-mir-9-1 1 19956200
hsa-miR-9 hsa-mir-9-2 5 19956200
hsa-miR-9 hsa-mir-9-3 15 19956200
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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