AutismKB 2.0

Annotation Detail for HSPB3


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Basic Information Top
Gene Symbol:HSPB3 ( DHMN2C,HMN2C,HSPL27 )
Gene Full Name: heat shock 27kDa protein 3
Band: 5q11.2
Quick LinksEntrez ID:8988; OMIM: 604624; Uniprot ID:HSPB3_HUMAN; ENSEMBL ID: ENSG00000169271; HGNC ID: 5248
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
58O-linkedHMM predict
62Phosphothreonine(CDC2)HMM predict
62Phosphothreonine(MAPK)HMM predict
62Phosphothreonine(CDK)HMM predict
62PhosphothreonineHMM predict
113Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006308
  • Location:chr5 53787201-53787963
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 53774534 53774627 93 12621
TAF HelaGSE8489 53773706 53774660 954 13019
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 53791958 53792490 532 4261
P300 T30-glioblastomaGSE21026 53788447 53789441 994 981
Rb GrowingGSE19898 53807181 53807389 208 19322
p130 shRbSenescentGSE19898 53802386 53802613 227 14536
No data
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018